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Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and related derivatives

Journal of medicinal chemistry, 1993-09, Vol.36 (19), p.2801-2809

1993

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Synthesis and Antitumor Activity of 4-Aminomethylthioxanthenone and 5-Aminomethylbenzothiopyranoindazole Derivatives

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3645-3654

1998

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Synthesis and Antibacterial Activity of Some Novel 1-Substituted 1,4-Dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic Acids. Potent Antistaphylococcal Agents

Journal of medicinal chemistry, 1995-07, Vol.38 (14), p.2531-2540

1995

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Antitumour activity of N-[[1-[[2-(diethylamino)ethyl]amino]-9-oxo-9H-thioxanthen-4-yl]methyl]methanesulfonamide (WIN33377) and analogues

Expert opinion on investigational drugs, 1994-12, Vol.3 (12), p.1281-1292

1994

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Mechanism of action and antitumor activity of (S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyridol[1,2,3-de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161)

Biochemical pharmacology, 1995-06, Vol.50 (1), p.111-122

1995

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The antitumor activity of novel pyrazoloquinoline derivatives

Bioorganic & medicinal chemistry letters, 1995-02, Vol.5 (4), p.405-410

1995

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3-benzyl-quinolones: Novel, potent inhibitors of mammalian topoisomerase II

Bioorganic & medicinal chemistry letters, 1995-05, Vol.5 (9), p.1021-1026

1995

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Cyclic variations of SR 233377 (WIN 33377) and effects on antitumor activity

Bioorganic & medicinal chemistry letters, 1996-06, Vol.6 (12), p.1345-1350

1996

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Potent mammalian topoisomerase II inhibitors: 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-substituted-quinolines

Bioorganic & medicinal chemistry letters, 1995-02, Vol.5 (4), p.399-404

1995

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Mechanism of action and antitumor activity of ( S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7 H-pyridol [1,2,3- de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161)

Biochemical pharmacology, 1995-06, Vol.50 (1), p.111-122

1995

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Relationship of structure of bridged (2,6-dimethyl-4-pyridinyl)quinolones to mammalian topoisomerase II inhibition

Bioorganic & medicinal chemistry letters, 1993-08, Vol.3 (8), p.1711-1716

1993

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5′,5‴-P 1 , P 4 Diadenosine Tetraphosphate (Ap 4 A): A Putative Initiator of DNA Replication

Cancer investigation, 1985-01, Vol.3 (5), p.465-471

1985

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5′,5 -P1, P4 Diadenosine Tetraphosphate (Ap4A): A Putative Initiator of DNA Replication

Cancer investigation, 1985, Vol.3 (5), p.465-471

1985

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Two-dimensional zymogram analysis of nucleases in Bacillus subtilis

Analytical biochemistry, 1983-01, Vol.133 (2), p.322-329

1983

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Coordinated Changes in Competence Associated Polypeptides among Transformation Defective Mutants of B. subtilis

Molecular Cloning and Gene Regulation in Bacilli, 1982, p.227-236

1982

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Human monoclonal antibodies against highly conserved HR1 and HR2 domains of the SARS-CoV spike protein are more broadly neutralizing

PloS one, 2012-11, Vol.7 (11), p.e50366-e50366

2012

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Reliability Correction is Key for Robust Kepler Occurrence Rates

The Astronomical journal, 2020-11, Vol.160 (5), p.200

2020

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Discovery and Vetting of Exoplanets. I. Benchmarking K2 Vetting Tools

The Astronomical journal, 2019-03, Vol.157 (3), p.124

2019

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Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

The Journal of experimental medicine, 2010-01, Vol.207 (1), p.17-27

2010

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Measuring Transit Signal Recovery in the Kepler Pipeline. IV. Completeness of the DR25 Planet Candidate Catalog

The Astronomical journal, 2020-10, Vol.160 (4), p.159

2020

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Developing interactions with industry in rare diseases: lessons learned and continuing challenges

Genetics in medicine, 2020, Vol.22 (1), p.219-226

2020

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PLANETARY CANDIDATES OBSERVED BY KEPLER. VII. THE FIRST FULLY UNIFORM CATALOG BASED ON THE ENTIRE 48-MONTH DATA SET (Q1-Q17 DR24)

The Astrophysical journal. Supplement series, 2016-05, Vol.224 (1), p.12-12

2016

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TERRESTRIAL PLANET OCCURRENCE RATES FOR THE KEPLER GK DWARF SAMPLE

The Astrophysical journal, 2015-08, Vol.809 (1), p.1-19

2015

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The TESS Objects of Interest Catalog from the TESS Prime Mission

The Astrophysical journal. Supplement series, 2021-06, Vol.254 (2), p.39

2021

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Kepler's Earth-like Planets Should Not Be Confirmed without Independent Detection: The Case of Kepler-452b

The Astronomical journal, 2018-05, Vol.155 (5), p.210

2018

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Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and related derivatives

Synthesis and Antitumor Activity of 4-Aminomethylthioxanthenone and 5-Aminomethylbenzothiopyranoindazole Derivatives

Synthesis and Antibacterial Activity of Some Novel 1-Substituted 1,4-Dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic Acids. Potent Antistaphylococcal Agents

Antitumour activity of N-[[1-[[2-(diethylamino)ethyl]amino]-9-oxo-9H-thioxanthen-4-yl]methyl]methanesulfonamide (WIN33377) and analogues

Mechanism of action and antitumor activity of (S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyridol[1,2,3-de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161)

The antitumor activity of novel pyrazoloquinoline derivatives

3-benzyl-quinolones: Novel, potent inhibitors of mammalian topoisomerase II

Cyclic variations of SR 233377 (WIN 33377) and effects on antitumor activity

Potent mammalian topoisomerase II inhibitors: 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-substituted-quinolines

Mechanism of action and antitumor activity of ( S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7 H-pyridol [1,2,3- de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161)

Relationship of structure of bridged (2,6-dimethyl-4-pyridinyl)quinolones to mammalian topoisomerase II inhibition

5′,5‴-P 1 , P 4 Diadenosine Tetraphosphate (Ap 4 A): A Putative Initiator of DNA Replication

5′,5 -P1, P4 Diadenosine Tetraphosphate (Ap4A): A Putative Initiator of DNA Replication

Two-dimensional zymogram analysis of nucleases in Bacillus subtilis

Coordinated Changes in Competence Associated Polypeptides among Transformation Defective Mutants of B. subtilis

Human monoclonal antibodies against highly conserved HR1 and HR2 domains of the SARS-CoV spike protein are more broadly neutralizing

Reliability Correction is Key for Robust Kepler Occurrence Rates

Discovery and Vetting of Exoplanets. I. Benchmarking K2 Vetting Tools

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

Measuring Transit Signal Recovery in the Kepler Pipeline. IV. Completeness of the DR25 Planet Candidate Catalog

Developing interactions with industry in rare diseases: lessons learned and continuing challenges

PLANETARY CANDIDATES OBSERVED BY KEPLER. VII. THE FIRST FULLY UNIFORM CATALOG BASED ON THE ENTIRE 48-MONTH DATA SET (Q1-Q17 DR24)

TERRESTRIAL PLANET OCCURRENCE RATES FOR THE KEPLER GK DWARF SAMPLE

The TESS Objects of Interest Catalog from the TESS Prime Mission

Kepler's Earth-like Planets Should Not Be Confirmed without Independent Detection: The Case of Kepler-452b

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