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Factors Which Contribute to the Immunogenicity of Non-replicating Adenoviral Vectored Vaccines

Frontiers in immunology, 2020-05, Vol.11, p.909-909

Coughlan, Lynda

2020

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Overcoming Barriers in the Path to a Universal Influenza Virus Vaccine

Cell host & microbe, 2018-07, Vol.24 (1), p.18-24

2018

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Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

Science (American Association for the Advancement of Science), 2021-02, Vol.371 (6532), p.926-931

2021

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Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus

PLoS biology, 2021-12, Vol.19 (12), p.e3001384-e3001384

2021

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Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model

mBio, 2021-03, Vol.12 (2)

2021

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Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection

Emerging microbes & infections, 2020-01, Vol.9 (1), p.2433-2445

2020

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Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

Molecular therapy, 2014-03, Vol.22 (3), p.668-674

2014

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Adenoviral Vectors as Vaccines for Emerging Avian Influenza Viruses

Frontiers in immunology, 2021-01, Vol.11, p.607333-607333

2021

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Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions

Nature communications, 2019-02, Vol.10 (1), p.741-741, Article 741

2019

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A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses

Nature communications, 2021-10, Vol.12 (1), p.6197-6197, Article 6197

2021

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Enhancing the protection of influenza virus vaccines with BECC TLR4 adjuvant in aged mice

Scientific reports, 2023-01, Vol.13 (1), p.715-715, Article 715

2023

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Snatching the Crown from SARS-CoV-2

Cell host & microbe, 2020-09, Vol.28 (3), p.360-363

Coughlan, Lynda

2020

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RIG-I and TLR-7/8 agonists as combination adjuvant shapes unique antibody and cellular vaccine responses to seasonal influenza vaccine

Frontiers in immunology, 2022-11, Vol.13, p.974016

2022

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Measuring Cellular Immunity to Influenza: Methods of Detection, Applications and Challenges

Vaccines, 2015-04, Vol.3 (2), p.293-319

2015

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Always a bridesmaid, never a bride: Committing to flu neuraminidase as a vaccine target

Molecular therapy, 2023-07, Vol.31 (7), p.1865-1867

2023

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Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

Blood, 2010-10, Vol.116 (15), p.2656-2664

2010

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Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice

Molecular therapy. Methods & clinical development, 2020-03, Vol.16, p.108-125

2020

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Viral platform engineering for targeted gene delivery to human hematopoietic stem cells

Molecular therapy, 2024-01, Vol.32 (1), p.6-8

2024

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Trivalent NDV-HXP-S Vaccine Protects against Phylogenetically Distant SARS-CoV-2 Variants of Concern in Mice

Microbiology spectrum, 2022-06, Vol.10 (3), p.e0153822-e0153822

2022

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Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses

Cell reports. Medicine, 2021-12, Vol.2 (12), p.100484-100484, Article 100484

Coughlan, Lynda

2021

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The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination

npj vaccines, 2022-08, Vol.7 (1), p.103-103, Article 103

2022

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Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X

PLoS pathogens, 2010-10, Vol.6 (10), p.e1001142-e1001142

2010

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Tropism-modification strategies for targeted gene delivery using adenoviral vectors

Viruses, 2010-10, Vol.2 (10), p.2290-2355

2010

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In Vivo Retargeting of Adenovirus Type 5 to αvβ6 Integrin Results in Reduced Hepatotoxicity and Improved Tumor Uptake following Systemic Delivery

Journal of Virology, 2009-07, Vol.83 (13), p.6416-6428

2009

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Factors Which Contribute to the Immunogenicity of Non-replicating Adenoviral Vectored Vaccines

Overcoming Barriers in the Path to a Universal Influenza Virus Vaccine

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus

Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model

Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection

Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

Adenoviral Vectors as Vaccines for Emerging Avian Influenza Viruses

Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions

A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses

Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses

Enhancing the protection of influenza virus vaccines with BECC TLR4 adjuvant in aged mice

Snatching the Crown from SARS-CoV-2

RIG-I and TLR-7/8 agonists as combination adjuvant shapes unique antibody and cellular vaccine responses to seasonal influenza vaccine

Measuring Cellular Immunity to Influenza: Methods of Detection, Applications and Challenges

Always a bridesmaid, never a bride: Committing to flu neuraminidase as a vaccine target

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

Targeting Antigen to the Surface of EVs Improves the In Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice

Viral platform engineering for targeted gene delivery to human hematopoietic stem cells

Trivalent NDV-HXP-S Vaccine Protects against Phylogenetically Distant SARS-CoV-2 Variants of Concern in Mice

Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses

The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination

Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X

Tropism-modification strategies for targeted gene delivery using adenoviral vectors

In Vivo Retargeting of Adenovirus Type 5 to αvβ6 Integrin Results in Reduced Hepatotoxicity and Improved Tumor Uptake following Systemic Delivery

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