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From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design

Molecules (Basel, Switzerland), 2023-10, Vol.28 (20), p.7089

2023

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From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design

Molecules (Basel, Switzerland), 2024-02, Vol.29 (4), p.815

2024

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Novel N -normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

Molecules (Basel, Switzerland), 2022-08, Vol.27 (16), p.5135

2022

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New Insights into the Opioid Analgesic Profile of cis -(-)- N -Normetazocine-derived Ligands

Molecules (Basel, Switzerland), 2023-06, Vol.28 (12), p.4827

2023

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Pulmonary Arteriovenous Malformations (PAVMs) and Pregnancy: A Rare Case of Hemothorax and Review of the Literature

Case reports in obstetrics and gynecology, 2019, Vol.2019 (2019), p.1-4

2019

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Two-step synthesis of enantiomerically pure morphans from (R)-carvone

ChemMedChem, 2024-10, p.e202400596

2024

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Designing drugs optimized for both blood-brain barrier permeation and intra-cerebral partition

Expert opinion on drug discovery, 2024-03, Vol.19 (3), p.1-329

2024

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Design, synthesis, in vitro evaluation, and molecular modeling studies of N‐substituted benzomorphans, analogs of LP2, as novel MOR ligands

Chemical biology & drug design, 2023-06, Vol.101 (6), p.1382-1392

2023

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Development of selective sigma-1 receptor ligands with antiallodynic activity: a focus on piperidine and piperazine scaffolds

European journal of medicinal chemistry, 2024-11, p.117037, Article 117037

2024

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Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain

Molecular neurobiology, 2024-05, Vol.61 (5), p.2672-2685

2024

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New Insights into the Opioid Analgesic Profile of Icis/I--IN/I-Normetazocine-derived Ligands

Molecules (Basel, Switzerland), 2023-06, Vol.28 (12)

2023

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Novel IN/I-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

Molecules (Basel, Switzerland), 2022-08, Vol.27 (16)

2022

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Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

Journal of medicinal chemistry, 2023-08, Vol.66 (16), p.11447-11463

2023

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Wilkie’s syndrome

Journal of ultrasound, 2017-12, Vol.20 (4), p.339-342

2017

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Thyroid adenolipoma: a case report

Journal of ultrasound, 2018-06, Vol.21 (2), p.165-168

2018

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Copeman nodule: a case report

Journal of ultrasound, 2017-09, Vol.20 (3), p.251-252

2017

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Pulmonary Arteriovenous Malformations (PAVMs) and Pregnancy: A Rare Case of Hemothorax and Review of the Literature

Case reports in obstetrics and gynecology, 2019, Vol.2019, p.8165791-8165791

2019

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Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the treatment of patients with metastatic colorectal cancer (TRIBE2): a multicentre, open-label, phase 3, randomised, controlled trial

The lancet oncology, 2020-04, Vol.21 (4), p.497-507

2020

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Assessment of Marine Litter in the Coralligenous Habitat of a Marine Protected Area along the Ionian Coast of Sicily (Central Mediterranean)

Journal of marine science and engineering, 2020-09, Vol.8 (9), p.656

2020

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Caregiver burden and its related factors in advanced Parkinson’s disease: data from the PREDICT study

Journal of neurology, 2018-05, Vol.265 (5), p.1124-1137

2018

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Prognosis and determinants of serum PTH changes over time in 1-5 CKD stage patients followed in tertiary care

PloS one, 2018-08, Vol.13 (8), p.e0202417-e0202417

2018

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Long-term efficacy of lipoprotein apheresis and lomitapide in the treatment of homozygous familial hypercholesterolemia (HoFH): a cross-national retrospective survey

Orphanet journal of rare diseases, 2021-09, Vol.16 (1), p.1-381, Article 381

2021

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Ecological Status of Coralligenous Macroalgal Assemblages in the Marine Protected Area (MPA) Isole Ciclopi (Ionian Sea)

Plants (Basel), 2021-02, Vol.10 (2), p.329

2021

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Endoscopic ultrasonic aspirator–assisted removal of a third ventricular colloid cyst

Child's nervous system, 2023-12, Vol.39 (12), p.3391-3395

2023

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Kaledo, a board game for nutrition education of children and adolescents at school: cluster randomized controlled trial of healthy lifestyle promotion

European journal of pediatrics, 2015-02, Vol.174 (2), p.217-228

2015

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From Plant to Chemistry: Sources of Active Opioid Antinociceptive Principles for Medicinal Chemistry and Drug Design

From Plant to Chemistry: Sources of Antinociceptive Non-Opioid Active Principles for Medicinal Chemistry and Drug Design

Novel N -normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

New Insights into the Opioid Analgesic Profile of cis -(-)- N -Normetazocine-derived Ligands

Pulmonary Arteriovenous Malformations (PAVMs) and Pregnancy: A Rare Case of Hemothorax and Review of the Literature

Two-step synthesis of enantiomerically pure morphans from (R)-carvone

Designing drugs optimized for both blood-brain barrier permeation and intra-cerebral partition

Design, synthesis, in vitro evaluation, and molecular modeling studies of N‐substituted benzomorphans, analogs of LP2, as novel MOR ligands

Development of selective sigma-1 receptor ligands with antiallodynic activity: a focus on piperidine and piperazine scaffolds

Sigma-1 Receptor Inhibition Reduces Mechanical Allodynia and Modulate Neuroinflammation in Chronic Neuropathic Pain

New Insights into the Opioid Analgesic Profile of Icis/I--IN/I-Normetazocine-derived Ligands

Novel IN/I-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

Wilkie’s syndrome

Thyroid adenolipoma: a case report

Copeman nodule: a case report

Pulmonary Arteriovenous Malformations (PAVMs) and Pregnancy: A Rare Case of Hemothorax and Review of the Literature

Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the treatment of patients with metastatic colorectal cancer (TRIBE2): a multicentre, open-label, phase 3, randomised, controlled trial

Assessment of Marine Litter in the Coralligenous Habitat of a Marine Protected Area along the Ionian Coast of Sicily (Central Mediterranean)

Caregiver burden and its related factors in advanced Parkinson’s disease: data from the PREDICT study

Prognosis and determinants of serum PTH changes over time in 1-5 CKD stage patients followed in tertiary care

Long-term efficacy of lipoprotein apheresis and lomitapide in the treatment of homozygous familial hypercholesterolemia (HoFH): a cross-national retrospective survey

Ecological Status of Coralligenous Macroalgal Assemblages in the Marine Protected Area (MPA) Isole Ciclopi (Ionian Sea)

Endoscopic ultrasonic aspirator–assisted removal of a third ventricular colloid cyst

Kaledo, a board game for nutrition education of children and adolescents at school: cluster randomized controlled trial of healthy lifestyle promotion

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