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Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

Journal of the American Chemical Society, 2017-03, Vol.139 (9), p.3446-3455

2017

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Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (5), p.2406-2411

2020

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A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin

Journal of the American Chemical Society, 2019-02, Vol.141 (7), p.2960-2974

2019

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Targeted Degradation of a Hypoxia-Associated Non-coding RNA Enhances the Selectivity of a Small Molecule Interacting with RNA

Cell chemical biology, 2019-08, Vol.26 (8), p.1180-1186.e5

2019

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Small Molecule Targeted Recruitment of a Nuclease to RNA

Journal of the American Chemical Society, 2018-06, Vol.140 (22), p.6741-6744

2018

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How We Think about Targeting RNA with Small Molecules

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.8880-8900

2020

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Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogen colonization

Biomolecules, 2015-05, Vol.5 (2), p.775-792

2015

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Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (3), p.1457-1467

2020

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Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs

Cell chemical biology, 2018-09, Vol.25 (9), p.1086-1094.e7

2018

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Programming inactive RNA-binding small molecules into bioactive degraders

Nature (London), 2023-06, Vol.618 (7963), p.169-179

2023

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Adding Broccoli to the Biosensor Menu

Cell chemical biology, 2019-04, Vol.26 (4), p.463-465

2019

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Extracellular adenosine produced by ecto-5′-nucleotidase (CD73) regulates macrophage pro-inflammatory responses, nitric oxide production, and favors Salmonella persistence

Nitric oxide, 2018-01, Vol.72 (C), p.7-15

2018

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Identifying and validating small molecules interacting with RNA (SMIRNAs)

Methods in enzymology, 2019, Vol.623, p.45-66

2019

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Gini Coefficients as a Single Value Metric to Define Chemical Probe Selectivity

ACS chemical biology, 2020-08, Vol.15 (8), p.2031-2040

2020

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Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA

Bioorganic & medicinal chemistry letters, 2016-06, Vol.26 (11), p.2605-2609

2016

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A clipped [3]rotaxane derived from bis-nor-seco-cucurbit[10]uril

Chemical communications (Cambridge, England), 2011-09, Vol.47 (33), p.9420-9422

2011

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A clipped [3]rotaxane derived from bis-nor-seco-cucurbit[10]uril

Chemical communications (Cambridge, England), 2011, Vol.47 (33), p.9420

2011

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Targeted small molecule degradation of a hypoxia-associated non-coding RNA enhances the selectivity of an RNA targeted small molecule

Cell chemical biology, 2019-05, Vol.26 (8), p.1180-1186.e5

2019

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Strategies to Optimize the Selectivity of Small Molecules Targeting RNA

Costales, Matthew G

2019

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ProQuest

Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching

RNA Therapeutics, 2018, p.1-16

2018

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Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi

Frontiers in cellular and infection microbiology, 2021-03, Vol.11, p.614665-614665

2021

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Performance of Xpert Ultra nasopharyngeal swab for identification of tuberculosis deaths in northern Tanzania

Clinical microbiology and infection, 2022-08, Vol.28 (8), p.1150-1150.e6

2022

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Improving Pain Management and Long-Term Outcomes Following High-Energy Orthopaedic Trauma (Pain Study)

Journal of orthopaedic trauma, 2017-04, Vol.31 Suppl 1 (1), p.S71-S77

2017

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Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer

A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin

Targeted Degradation of a Hypoxia-Associated Non-coding RNA Enhances the Selectivity of a Small Molecule Interacting with RNA

Small Molecule Targeted Recruitment of a Nuclease to RNA

How We Think about Targeting RNA with Small Molecules

Extracellular adenosine generation in the regulation of pro-inflammatory responses and pathogen colonization

Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA

Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs

Programming inactive RNA-binding small molecules into bioactive degraders

Adding Broccoli to the Biosensor Menu

Extracellular adenosine produced by ecto-5′-nucleotidase (CD73) regulates macrophage pro-inflammatory responses, nitric oxide production, and favors Salmonella persistence

Identifying and validating small molecules interacting with RNA (SMIRNAs)

Gini Coefficients as a Single Value Metric to Define Chemical Probe Selectivity

Comparison of small molecules and oligonucleotides that target a toxic, non-coding RNA

A clipped [3]rotaxane derived from bis-nor-seco-cucurbit[10]uril

A clipped [3]rotaxane derived from bis-nor-seco-cucurbit[10]uril

Targeted small molecule degradation of a hypoxia-associated non-coding RNA enhances the selectivity of an RNA targeted small molecule

Strategies to Optimize the Selectivity of Small Molecules Targeting RNA

Computational Tools for Design of Selective Small Molecules Targeting RNA: From Small Molecule Microarrays to Chemical Similarity Searching

Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi

Performance of Xpert Ultra nasopharyngeal swab for identification of tuberculosis deaths in northern Tanzania

Improving Pain Management and Long-Term Outcomes Following High-Energy Orthopaedic Trauma (Pain Study)

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