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Safety Issues Specific to Clinical Development of Protein Therapeutics

Clinical pharmacology and therapeutics, 2008-11, Vol.84 (5), p.624-627

2008

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AB0282 SAFETY, TOLERABILITY AND SELECTIVE EXPANSION OF REGULATORY T CELLS BY A SINGLE DOSE OF THE NOVEL IL-2 MUTEIN PT101 IN A PHASE 1 STUDY IN HEALTHY VOLUNTEERS

Annals of the rheumatic diseases, 2021-06, Vol.80 (Suppl 1), p.1167-1167

2021

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Phase I/II trial of recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer in patients with active refractory rheumatoid arthritis

Journal of rheumatology, 2000-03, Vol.27 (3), p.601

2000

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Pharmacokinetics, immunogenicity, and efficacy of dimeric TNFR binding proteins in healthy and bacteremic baboon

Journal of applied physiology (1985), 1998-04, Vol.84 (4), p.1119-1130

1998

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Effects of chlorpyrifos on neuronal development in rat embryo midbrain micromass cultures

Veterinary and human toxicology, 1995-04, Vol.37 (2), p.118

1995

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Prediction of Nephrotoxicant Action and Identification of Candidate Toxicity-Related Biomarkers

Toxicologic pathology, 2005-01, Vol.33 (3), p.343-355

2005

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Mesoscopic model for binary fluids

Frontiers of physics, 2017-10, Vol.12 (5), p.231-239, Article 128703

2017

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Design of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) for chronic inflammatory diseases

Advanced drug delivery reviews, 2003-09, Vol.55 (10), p.1315-1336

2003

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Video-electroencephalography prolonged monitoring in patients with ambulatory diagnosis of medically refractory temporal lobe epilepsy: application of fuzzy logic's model

Revista de neurologiá, 2006-07, Vol.43 (1), p.7-14

2006

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A Toxicity Profile of Osteoprotegerin in the Cynomolgus Monkey

International journal of toxicology, 2003-09, Vol.22 (5), p.403-412

2003

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E. H. Wilkins, The Prose Letter of Petrarch (Book Review)

Speculum; a Journal of Mediaeval Studies, 1953, Vol.28 (1), p.224

Cosenza, M E

1953

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E. H. Wilkins, The Making of the Canzoniere and other Petrarchan Studies (Book Review)

Speculum; a Journal of Mediaeval Studies, 1953, Vol.28 (1), p.222

Cosenza, M E

1953

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The establishment of the College of the city of New York as the free academy in 1847: Townsend Harris, founder; a chapter in the history of education

College of the city of N.Y., 1925. 234 pp, 1925

Cosenza, M E

1925

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Against mass media trends: Minority growth in cultural globalization

PloS one, 2020-04, Vol.15 (4), p.e0230923-e0230923

2020

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Ecogenomics and metabolic potential of the South Atlantic Ocean microbiome

The Science of the total environment, 2021-04, Vol.765, p.142758-142758, Article 142758

2021

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A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling

Cell, 2016-04, Vol.165 (3), p.643-655

2016

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Soluble PD-L1 and Circulating CD8+PD-1+ and NK Cells Enclose a Prognostic and Predictive Immune Effector Score in Immunotherapy Treated NSCLC patients

Lung cancer (Amsterdam, Netherlands), 2020-10, Vol.148, p.1-11

2020

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ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent

Cancer cell, 2005-03, Vol.7 (3), p.275-286

2005

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Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

Nature communications, 2021-08, Vol.12 (1), p.4671-4671, Article 4671

2021

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Resistance to osimertinib in advanced EGFR-mutated NSCLC: a prospective study of molecular genotyping on tissue and liquid biopsies

British journal of cancer, 2024-01, Vol.130 (1), p.135-142

2024

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ON01210.Na (Ex-RAD®) mitigates radiation damage through activation of the AKT pathway

PloS one, 2013-03, Vol.8 (3), p.e58355

2013

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Controlling systemic corruption through group size and salary dispersion of public servants

Heliyon, 2024-02, Vol.10 (3), p.e25148-e25148, Article e25148

2024

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Discovery of a Clinical Stage Multi-Kinase Inhibitor Sodium (E)-2-{2-Methoxy-5-[(2′,4′,6′-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): Synthesis, Structure–Activity Relationship, and Biological Activity

Journal of medicinal chemistry, 2011-09, Vol.54 (18), p.6254-6276

2011

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A Non-ATP-Competitive Inhibitor of BCR-ABL Overrides Imatinib Resistance

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (6), p.1992-1997

2005

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A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent

Molecular cell, 2020-07, Vol.79 (1), p.180-190.e4

2020

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Safety Issues Specific to Clinical Development of Protein Therapeutics

AB0282 SAFETY, TOLERABILITY AND SELECTIVE EXPANSION OF REGULATORY T CELLS BY A SINGLE DOSE OF THE NOVEL IL-2 MUTEIN PT101 IN A PHASE 1 STUDY IN HEALTHY VOLUNTEERS

Phase I/II trial of recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer in patients with active refractory rheumatoid arthritis

Pharmacokinetics, immunogenicity, and efficacy of dimeric TNFR binding proteins in healthy and bacteremic baboon

Effects of chlorpyrifos on neuronal development in rat embryo midbrain micromass cultures

Prediction of Nephrotoxicant Action and Identification of Candidate Toxicity-Related Biomarkers

Mesoscopic model for binary fluids

Design of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) for chronic inflammatory diseases

Video-electroencephalography prolonged monitoring in patients with ambulatory diagnosis of medically refractory temporal lobe epilepsy: application of fuzzy logic's model

A Toxicity Profile of Osteoprotegerin in the Cynomolgus Monkey

E. H. Wilkins, The Prose Letter of Petrarch (Book Review)

E. H. Wilkins, The Making of the Canzoniere and other Petrarchan Studies (Book Review)

The establishment of the College of the city of New York as the free academy in 1847: Townsend Harris, founder; a chapter in the history of education

Against mass media trends: Minority growth in cultural globalization

Ecogenomics and metabolic potential of the South Atlantic Ocean microbiome

A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling

Soluble PD-L1 and Circulating CD8+PD-1+ and NK Cells Enclose a Prognostic and Predictive Immune Effector Score in Immunotherapy Treated NSCLC patients

ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

Resistance to osimertinib in advanced EGFR-mutated NSCLC: a prospective study of molecular genotyping on tissue and liquid biopsies

ON01210.Na (Ex-RAD®) mitigates radiation damage through activation of the AKT pathway

Controlling systemic corruption through group size and salary dispersion of public servants

Discovery of a Clinical Stage Multi-Kinase Inhibitor Sodium (E)-2-{2-Methoxy-5-[(2′,4′,6′-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): Synthesis, Structure–Activity Relationship, and Biological Activity

A Non-ATP-Competitive Inhibitor of BCR-ABL Overrides Imatinib Resistance

A Contaminant Impurity, Not Rigosertib, Is a Tubulin Binding Agent

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