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Critical Roles of Glutamine as Nitrogen Donors in Purine and Pyrimidine Nucleotide Synthesis: Asparaginase Treatment in Childhood Acute Lymphoblastic Leukemia

In vivo (Athens), 2006-09, Vol.20 (5), p.587-589

2006

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Effects of PRIMA-1 on Wild-type L1210 Cells Expressing Mutant p53 and Drug-resistant L1210 Cells Lacking Expression of p53: Necrosis vs. Apoptosis

Anticancer research, 2006-03, Vol.26 (2A), p.1289-1295

2006

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Implications of the Involvement of the Endoplasmic Reticulum Stress Pathway in Drug-induced Apoptosis

Anticancer research, 2008-03, Vol.28 (2A), p.681-686

2008

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Understanding Interactions between and among Apoptosis Inducing Pathways in Tumor Cells

In vivo (Athens), 2007-03, Vol.21 (2), p.245-249

2007

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Blockage of Cyclin cdk's, PKC and Phosphoinositol 3-kinase Pathways Leads to Augmentation of Apoptosis in Drug-resistant Leukemia Cells: Evidence for Interactive Effects of Flavopiridol, LY 294002, Roscovitine, Wortmannin and UCN-01

Anticancer research, 2005-01, Vol.25 (1A), p.101-106

2005

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Synthesis and Biological Activity of 3- and 5-Amino Derivatives of Pyridine-2-carboxaldehyde Thiosemicarbazone

Journal of medicinal chemistry, 1996-06, Vol.39 (13), p.2586-2593

1996

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Phenolic Compounds, Sodium Salicylate and Related Compounds, as Inhibitors of Tumor Cell Growth and Inducers of Apoptosis in Mouse Leukemia L1210 Cells

In vivo (Athens), 2005-01, Vol.19 (1), p.31

2005

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Lipophilic derivatives of cyclam as new inhibitors of tumor cell growth

Chemical communications (Cambridge, England), 2002-01 (2), p.154-155

2002

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Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway

Cancer letters, 2007-01, Vol.245 (1), p.341-349

2007

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Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells

Anticancer research, 2002-11, Vol.22 (6C), p.3805

2002

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5-(3-carboxymethoxyphenyl)-2-(4,5-dimethylthiazolyl)-3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and related analogs of 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) reducing to purple water-soluble formazans As cell-viability indicators

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (11), p.611-614

1991

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Augmentation of apoptosis responses in p53-deficient L1210 cells by compounds directed at blocking NFkappaB activation

Anticancer research, 2001-11, Vol.21 (6A), p.3807

2001

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Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase

Biochemical pharmacology, 1997-09, Vol.54 (6), p.649-655

1997

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In vivo growth of mouse leukemia L1210 cells with metabolic alterations in the subunits of ribonucleotide reductase

In vivo (Athens), 2002-05, Vol.16 (3), p.175

2002

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Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity

Advances in enzyme regulation, 1999-01, Vol.39 (1), p.3-12

1999

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Altered steady-state levels of the messenger RNAs for c-myc and p53 in L1210 cell lines resistant to deoxyadenosine

Cancer research (Baltimore), 1992-04, Vol.52 (7), p.2000-2003

1992

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Inhibitors of ribonucleotide reductase: Comparative effects of amino- and hydroxy-substituted pyridine-2-carboxaldehydethiosemicarbazones

Biochemical pharmacology, 1994-07, Vol.48 (2), p.335-344

1994

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Induction of apoptosis in p53-deficient L1210 cells by an I-kappa-B-alpha-inhibitor (Bay 11-7085) via a NF-kappa-B-independent mechanism

Advances in enzyme regulation, 2005, Vol.45 (1), p.85-93

2005

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Gemcitabine-induced apoptosis in a drug-resistant mouse leukemia L1210 cell line that does not express p53

Advances in enzyme regulation, 2004, Vol.44 (1), p.11-25

2004

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Liver microsomal inactivation of 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone as an inhibitor of ribonucleotide reductase

Cancer research (Chicago, Ill.), 1988-11, Vol.48 (22), p.6375-6378

1988

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Apoptosis induced by inhibitors of nucleotide synthesis in deoxyadenosine-resistant leukemia L1210 cells that lack p53 expression

Anticancer research, 2000-11, Vol.20 (6B), p.4171

2000

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Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells

Anticancer research, 2001-01, Vol.21 (1A), p.173

2001

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Inhibitors of diverse metabolic steps cause increased apoptosis in deoxyadenosine-resistant mouse leukemia L1210 cells that lack p53 expression: convergence at caspase-3 activation

Advances in enzyme regulation, 2003-01, Vol.43 (1), p.29-45

2003

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Cellular Responses in Mouse Leukemia L1210 Cells Made Resistant to Deoxyadenosine

Biochemical and biophysical research communications, 1998-08, Vol.249 (3), p.687-691

1998

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Lack of competition of substrates for P-glycoprotein in MCF-7 breast cancer cells overexpressing MDR1

Advances in enzyme regulation, 1999-01, Vol.39 (1), p.113-128

1999

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Critical Roles of Glutamine as Nitrogen Donors in Purine and Pyrimidine Nucleotide Synthesis: Asparaginase Treatment in Childhood Acute Lymphoblastic Leukemia

Effects of PRIMA-1 on Wild-type L1210 Cells Expressing Mutant p53 and Drug-resistant L1210 Cells Lacking Expression of p53: Necrosis vs. Apoptosis

Implications of the Involvement of the Endoplasmic Reticulum Stress Pathway in Drug-induced Apoptosis

Understanding Interactions between and among Apoptosis Inducing Pathways in Tumor Cells

Blockage of Cyclin cdk's, PKC and Phosphoinositol 3-kinase Pathways Leads to Augmentation of Apoptosis in Drug-resistant Leukemia Cells: Evidence for Interactive Effects of Flavopiridol, LY 294002, Roscovitine, Wortmannin and UCN-01

Synthesis and Biological Activity of 3- and 5-Amino Derivatives of Pyridine-2-carboxaldehyde Thiosemicarbazone

Phenolic Compounds, Sodium Salicylate and Related Compounds, as Inhibitors of Tumor Cell Growth and Inducers of Apoptosis in Mouse Leukemia L1210 Cells

Lipophilic derivatives of cyclam as new inhibitors of tumor cell growth

Bis(2-hydroxybenzylidene)acetone, a potent inducer of the phase 2 response, causes apoptosis in mouse leukemia cells through a p53-independent, caspase-mediated pathway

Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells

5-(3-carboxymethoxyphenyl)-2-(4,5-dimethylthiazolyl)-3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and related analogs of 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) reducing to purple water-soluble formazans As cell-viability indicators

Augmentation of apoptosis responses in p53-deficient L1210 cells by compounds directed at blocking NFkappaB activation

Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase

In vivo growth of mouse leukemia L1210 cells with metabolic alterations in the subunits of ribonucleotide reductase

Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone; 3-AP): an inhibitor of ribonucleotide reductase with antineoplastic activity

Altered steady-state levels of the messenger RNAs for c-myc and p53 in L1210 cell lines resistant to deoxyadenosine

Inhibitors of ribonucleotide reductase: Comparative effects of amino- and hydroxy-substituted pyridine-2-carboxaldehydethiosemicarbazones

Induction of apoptosis in p53-deficient L1210 cells by an I-kappa-B-alpha-inhibitor (Bay 11-7085) via a NF-kappa-B-independent mechanism

Gemcitabine-induced apoptosis in a drug-resistant mouse leukemia L1210 cell line that does not express p53

Liver microsomal inactivation of 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone as an inhibitor of ribonucleotide reductase

Apoptosis induced by inhibitors of nucleotide synthesis in deoxyadenosine-resistant leukemia L1210 cells that lack p53 expression

Increased sensitivity to sodium salicylate-induced apoptosis in drug-resistant leukemia L1210 cells

Inhibitors of diverse metabolic steps cause increased apoptosis in deoxyadenosine-resistant mouse leukemia L1210 cells that lack p53 expression: convergence at caspase-3 activation

Cellular Responses in Mouse Leukemia L1210 Cells Made Resistant to Deoxyadenosine

Lack of competition of substrates for P-glycoprotein in MCF-7 breast cancer cells overexpressing MDR1

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