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Inflammatory cytokines compromise programmed cell death‐1 (PD‐1)‐mediated T cell suppression in inflammatory arthritis through up‐regulation of soluble PD‐1

Clinical and experimental immunology, 2017-06, Vol.188 (3), p.455-466

2017

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Resolution‐associated molecular patterns (RAMP): RAMParts defending immunological homeostasis?

Clinical and experimental immunology, 2011-09, Vol.165 (3), p.292-300

2011

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C-Terminal Deletions in the ALAS2 Gene Lead to Gain of Function and Cause X-linked Dominant Protoporphyria without Anemia or Iron Overload

American journal of human genetics, 2008-09, Vol.83 (3), p.408-414

2008

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Defective CD8+CD28− regulatory T cell suppressor function in rheumatoid arthritis is restored by tumour necrosis factor inhibitor therapy

Clinical and experimental immunology, 2013-10, Vol.174 (1), p.18-26

2013

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Crystal Structure of Protoporphyrinogen Oxidase from Myxococcus xanthus and Its Complex with the Inhibitor Acifluorfen

The Journal of biological chemistry, 2006-12, Vol.281 (50), p.38625-38633

2006

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FRI0159 Results of a Single Dose Ascending First-in-Man Trial of a Novel Biologic, Human Stress Protein Rasolvir (BIP) in Rheumatoid Arthritis (RA): The Ragulo Trial

Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.480-481

2015

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BiP regulates autoimmune inflammation and tissue damage

Autoimmunity reviews, 2006-02, Vol.5 (2), p.140-142

2006

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The Human Endoplasmic Reticulum Molecular Chaperone BiP Is an Autoantigen for Rheumatoid Arthritis and Prevents the Induction of Experimental Arthritis

The Journal of immunology (1950), 2001-02, Vol.166 (3), p.1492-1498

2001

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Systemic gene transfer of binding immunoglobulin protein (BiP) prevents disease progression in murine collagen‐induced arthritis

Clinical and experimental immunology, 2015-02, Vol.179 (2), p.210-219

2015

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Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts

Rheumatic diseases clinics of North America, 2001-05, Vol.27 (2), p.317-334

2001

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BiP, a putative autoantigen in rheumatoid arthritis, stimulates IL‐10‐producing CD8‐positive T cells from normal individuals

British journal of rheumatology, 2003-05, Vol.42 (5), p.637-644

2003

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Antibody response to the human stress protein BiP in rheumatoid arthritis

British journal of rheumatology, 2004-10, Vol.43 (10), p.1283-1287

2004

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A R59W mutation in human protoporphyrinogen oxidase results in decreased enzyme activity and is prevalent in South Africans with variegate porphyria

Nature genetics, 1996-05, Vol.13 (1), p.95-97

1996

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Stress cytokines: pivotal proteins in immune regulatory networks: Opinion

Current opinion in immunology, 2004-08, Vol.16 (4), p.531-534

2004

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Molecular characterization of erythropoietic protoporphyria in South Africa

British journal of dermatology (1951), 2008-07, Vol.159 (1), p.182-191

2008

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Functional IL-2 receptor beta (CD122) and gamma (CD132) chains are expressed by fibroblast-like synoviocytes: activation by IL-2 stimulates monocyte chemoattractant protein-1 production

The Journal of immunology (1950), 2001-03, Vol.166 (6), p.4141-4147

2001

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Fifty years of porphyria at the University of Cape Town

SAMJ: South African Medical Journal, 2012-06, Vol.102 (6), p.422-426

2012

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Kinetic and physical characterisation of recombinant wild-type and mutant human protoporphyrinogen oxidases

Biochimica et biophysica acta, 2003-08, Vol.1650 (1), p.10-21

2003

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Characterisation of the flavin adenine dinucleotide binding region of Myxococcus xanthus protoporphyrinogen oxidase

Biochemistry and biophysics reports, 2015-12, Vol.4, p.306-311

2015

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Autoantigens and immune pathways in rheumatoid arthritis

Critical reviews in immunology, 2002, Vol.22 (4), p.281

2002

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Pro-resolution immunological networks: binding immunoglobulin protein and other resolution-associated molecular patterns

Rheumatology (Oxford, England), 2012-05, Vol.51 (5), p.780-788

2012

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The relative proportions of secreted interleukin-2 and interleukin-10 determine the magnitude of rheumatoid arthritis T-cell proliferation to the recall antigen tuberculin purified protein derivative

Rheumatology (Oxford, England), 1999-12, Vol.38 (12), p.1203-1207

1999

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Autoantibodies to Posttranslationally Modified Type II Collagen as Potential Biomarkers for Rheumatoid Arthritis

Arthritis & rheumatology (Hoboken, N.J.), 2013-07, Vol.65 (7), p.1702-1712

2013

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023 Platelet activation induces phenotypic and functional changes in circulating monocytes as a consequence of monocyte–platelet aggregate formation

Heart (British Cardiac Society), 2010-06, Vol.96 (Suppl 1), p.A15-A16

2010

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Purification of and kinetic studies on a cloned protoporphyrinogen oxidase from the aerobic bacterium Bacillus subtilis

Archives of biochemistry and biophysics, 1998-10, Vol.358 (2), p.251-256

1998

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Inflammatory cytokines compromise programmed cell death‐1 (PD‐1)‐mediated T cell suppression in inflammatory arthritis through up‐regulation of soluble PD‐1

Resolution‐associated molecular patterns (RAMP): RAMParts defending immunological homeostasis?

C-Terminal Deletions in the ALAS2 Gene Lead to Gain of Function and Cause X-linked Dominant Protoporphyria without Anemia or Iron Overload

Defective CD8+CD28− regulatory T cell suppressor function in rheumatoid arthritis is restored by tumour necrosis factor inhibitor therapy

Crystal Structure of Protoporphyrinogen Oxidase from Myxococcus xanthus and Its Complex with the Inhibitor Acifluorfen

FRI0159 Results of a Single Dose Ascending First-in-Man Trial of a Novel Biologic, Human Stress Protein Rasolvir (BIP) in Rheumatoid Arthritis (RA): The Ragulo Trial

BiP regulates autoimmune inflammation and tissue damage

The Human Endoplasmic Reticulum Molecular Chaperone BiP Is an Autoantigen for Rheumatoid Arthritis and Prevents the Induction of Experimental Arthritis

Systemic gene transfer of binding immunoglobulin protein (BiP) prevents disease progression in murine collagen‐induced arthritis

Pathogenesis of rheumatoid arthritis. The role of T cells and other beasts

BiP, a putative autoantigen in rheumatoid arthritis, stimulates IL‐10‐producing CD8‐positive T cells from normal individuals

Antibody response to the human stress protein BiP in rheumatoid arthritis

A R59W mutation in human protoporphyrinogen oxidase results in decreased enzyme activity and is prevalent in South Africans with variegate porphyria

Stress cytokines: pivotal proteins in immune regulatory networks: Opinion

Molecular characterization of erythropoietic protoporphyria in South Africa

Functional IL-2 receptor beta (CD122) and gamma (CD132) chains are expressed by fibroblast-like synoviocytes: activation by IL-2 stimulates monocyte chemoattractant protein-1 production

Fifty years of porphyria at the University of Cape Town

Kinetic and physical characterisation of recombinant wild-type and mutant human protoporphyrinogen oxidases

Characterisation of the flavin adenine dinucleotide binding region of Myxococcus xanthus protoporphyrinogen oxidase

Autoantigens and immune pathways in rheumatoid arthritis

Pro-resolution immunological networks: binding immunoglobulin protein and other resolution-associated molecular patterns

The relative proportions of secreted interleukin-2 and interleukin-10 determine the magnitude of rheumatoid arthritis T-cell proliferation to the recall antigen tuberculin purified protein derivative

Autoantibodies to Posttranslationally Modified Type II Collagen as Potential Biomarkers for Rheumatoid Arthritis

023 Platelet activation induces phenotypic and functional changes in circulating monocytes as a consequence of monocyte–platelet aggregate formation

Purification of and kinetic studies on a cloned protoporphyrinogen oxidase from the aerobic bacterium Bacillus subtilis

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