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Fatty acid metabolism and insulin secretion in pancreatic beta cells

Diabetologia, 2003-10, Vol.46 (10), p.1297-1312

2003

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Signal transduction mechanisms in nutrient-induced insulin secretion

Diabetologia, 1997-07, Vol.40 Suppl 2, p.S32-S41

1997

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Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT)

Diabetes (New York, N.Y.), 2000-09, Vol.49 (9), p.1511-1516

2000

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Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression

Diabetes (New York, N.Y.), 1998-07, Vol.47 (7), p.1086-1094

1998

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The role of long-chain fatty acyl-CoA esters in β-cell signal transduction

The Journal of nutrition, 2000-02, Vol.130 (2), p.299S-304S

2000

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Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

The Journal of biological chemistry, 1992-03, Vol.267 (9), p.5802-5810

1992

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Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif

Diabetologia, 2007-08, Vol.50 (8), p.1670-1677

2007

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Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes

Diabetologia, 2004-02, Vol.47 (2), p.277-283

2004

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Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids

Diabetologia, 1997-04, Vol.40 (4), p.392-397

1997

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Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal beta-cells (HIT)

American journal of physiology: endocrinology and metabolism, 1996-10, Vol.271 (4), p.E702-E710

1996

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Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling

Diabetes (New York, N.Y.), 1996-02, Vol.45 (2), p.190-198

1996

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A Role for Malonyl-CoA in Glucose-Stimulated Insulin Secretion from Clonal Pancreatic β-Cells

The Journal of biological chemistry, 1989-12, Vol.264 (36), p.21608-21612

1989

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Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1

Diabetes (New York, N.Y.), 1997-03, Vol.46 (3), p.393-400

1997

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Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus

American journal of physiology: endocrinology and metabolism, 2004-12, Vol.287 (6), p.E1090-E1099

2004

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Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes

Biochemical journal, 1997-10, Vol.327 ( Pt 1) (1), p.225-231

1997

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Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells

Diabetes (New York, N.Y.), 2000-12, Vol.49 (12), p.2012-2020

2000

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Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets

The Journal of biological chemistry, 1991-05, Vol.266 (14), p.9314-9319

1991

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Changes in internal pH caused by movement of fatty acids into and out of clonal pancreatic beta-cells (HIT)

The Journal of biological chemistry, 1994-08, Vol.269 (33), p.20852-20856

1994

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Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis

Diabetes (New York, N.Y.), 2000-03, Vol.49 (3), p.383-391

2000

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Acyl-CoA esters modulate intracellular Ca2+ handling by permeabilized clonal pancreatic beta-cells

The Journal of biological chemistry, 1992-10, Vol.267 (28), p.19840-19845

1992

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Intracellular pH in Adipocytes: Effects of Free Fatty Acid Diffusion across the Plasma Membrane, Lipolytic Agonists, and Insulin

Proceedings of the National Academy of Sciences - PNAS, 1996-09, Vol.93 (19), p.10139-10144

1996

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Metabolic control ofβ-cell function

Seminars in cell & developmental biology, 2000-08, Vol.11 (4), p.267-275

2000

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Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria

The Journal of biological chemistry, 1986-02, Vol.261 (6), p.2567-2574

1986

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Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells

American journal of physiology: endocrinology and metabolism, 1999-09, Vol.277 (3), p.E521-E528

1999

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Acute Stimulation with Long Chain Acyl-CoA Enhances Exocytosis in Insulin-secreting Cells (HIT T-15 and NMRI β-Cells)

The Journal of biological chemistry, 2000-03, Vol.275 (13), p.9363-9368

2000

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Fatty acid metabolism and insulin secretion in pancreatic beta cells

Signal transduction mechanisms in nutrient-induced insulin secretion

Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT)

Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression

The role of long-chain fatty acyl-CoA esters in β-cell signal transduction

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif

Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes

Beta-cell hypersensitivity to glucose following 24-h exposure of rat islets to fatty acids

Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal beta-cells (HIT)

Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling

A Role for Malonyl-CoA in Glucose-Stimulated Insulin Secretion from Clonal Pancreatic β-Cells

Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1

Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus

Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyltransferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes

Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells

Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets

Changes in internal pH caused by movement of fatty acids into and out of clonal pancreatic beta-cells (HIT)

Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis

Acyl-CoA esters modulate intracellular Ca2+ handling by permeabilized clonal pancreatic beta-cells

Intracellular pH in Adipocytes: Effects of Free Fatty Acid Diffusion across the Plasma Membrane, Lipolytic Agonists, and Insulin

Metabolic control ofβ-cell function

Regulation of free and bound magnesium in rat hepatocytes and isolated mitochondria

Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells

Acute Stimulation with Long Chain Acyl-CoA Enhances Exocytosis in Insulin-secreting Cells (HIT T-15 and NMRI β-Cells)

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