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An ATG12-ATG5-TECPR1 E3-like complex regulates unconventional LC3 lipidation at damaged lysosomes

EMBO reports, 2023-09, Vol.24 (9), p.e56841-e56841

2023

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The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis

Nature chemical biology, 2019-07, Vol.15 (7), p.710-720

2019

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V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces non-canonical autophagy

The Journal of cell biology, 2022-12, Vol.221 (12), p.1

2022

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Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

Cancer cell, 2015-05, Vol.27 (5), p.682-697

2015

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ATG12-ATG5-TECPR1: an alternative E3-like complex utilized during the cellular response to lysosomal membrane damage

Autophagy, 2024-02, Vol.20 (2), p.443-444

2024

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Eating while intoxicated: characterizing the molecular mechanism behind V. cholerae toxin MakA-regulated autophagy

Autophagy, 2023-06, Vol.19 (6), p.1885-1886

2023

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Leukaemia xenotransplantation in zebrafish – chemotherapy response assay in vivo

British journal of haematology, 2011-06, Vol.153 (6), p.786-789

2011

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Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor

Angewandte Chemie International Edition, 2020-07, Vol.59 (30), p.12470-12476

International ed. in English, 2020

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Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy

Journal of cell science, 2021-03, Vol.134 (5)

2021

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Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia

Haematologica (Roma), 2015-01, Vol.100 (1), p.70-76

2015

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Ultrafast and selective labeling of endogenous proteins using affinity-based benzotriazole chemistry

Chemical science (Cambridge), 2022-06, Vol.13 (24), p.724-7246

2022

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Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

Angewandte Chemie International Edition, 2020-03, Vol.59 (14), p.5721-5729

International ed. in English, 2020

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A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation

Proceedings of the National Academy of Sciences - PNAS, 2024-04, Vol.121 (17), p.e2317680121

2024

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Modulation of autophagy by the novel mitochondrial complex I inhibitor Authipyrin

Bioorganic & medicinal chemistry, 2019-06, Vol.27 (12), p.2444-2448

2019

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Connecting the speckles: Splicing kinases and their role in tumorigenesis and treatment response

Nucleus (Austin, Tex.), 2015, Vol.6 (4), p.279-288

2015

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Estrogen receptor alpha (ESR1)-signaling regulates the expression of the taxane-response biomarker PRP4K

Experimental cell research, 2016-01, Vol.340 (1), p.125-131

2016

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PRP4K is a HER2-regulated modifier of taxane sensitivity

Cell cycle (Georgetown, Tex.), 2015, Vol.14 (7), p.1059-1069

2015

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Investigations regarding the utility of prodigiosenes to treat leukemia

Organic & biomolecular chemistry, 2013-01, Vol.11 (1), p.62-68

2013

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Synthesis and biological evaluation of prodigiosene conjugates of porphyrin, estrone and 4-hydroxytamoxifen

Bioorganic & medicinal chemistry, 2013-10, Vol.21 (19), p.5995-6002

2013

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Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor

Angewandte Chemie, 2020-07, Vol.132 (30), p.12570-12576

2020

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Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation

Angewandte Chemie International Edition, 2022-03, Vol.61 (11), p.e202114328-n/a

International ed. in English, 2022

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Inducin Triggers LC3‐Lipidation and ESCRT‐Mediated Lysosomal Membrane Repair

Chembiochem : a European journal of chemical biology, 2023-12, Vol.24 (24), p.e202300579-n/a

2023

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Human Leukemia Xenotransplantation Into Zebrafish Embryos as An In Vivo Assay for Chemotherapy Drug Response

Blood, 2010-11, Vol.116 (21), p.1704-1704

2010

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Abstract 4251: Evaluating novel targeted therapeutic agents in T-cell acute lymphoblastic leukemia using a zebrafish xenotransplantation model

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.4251-4251

2012

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Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation

Angewandte Chemie, 2022-03, Vol.134 (11), p.n/a

2022

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An ATG12-ATG5-TECPR1 E3-like complex regulates unconventional LC3 lipidation at damaged lysosomes

The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis

V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces non-canonical autophagy

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

ATG12-ATG5-TECPR1: an alternative E3-like complex utilized during the cellular response to lysosomal membrane damage

Eating while intoxicated: characterizing the molecular mechanism behind V. cholerae toxin MakA-regulated autophagy

Leukaemia xenotransplantation in zebrafish – chemotherapy response assay in vivo

Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor

Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy

Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia

Ultrafast and selective labeling of endogenous proteins using affinity-based benzotriazole chemistry

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor

A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation

Modulation of autophagy by the novel mitochondrial complex I inhibitor Authipyrin

Connecting the speckles: Splicing kinases and their role in tumorigenesis and treatment response

Estrogen receptor alpha (ESR1)-signaling regulates the expression of the taxane-response biomarker PRP4K

PRP4K is a HER2-regulated modifier of taxane sensitivity

Investigations regarding the utility of prodigiosenes to treat leukemia

Synthesis and biological evaluation of prodigiosene conjugates of porphyrin, estrone and 4-hydroxytamoxifen

Phenotyping Reveals Targets of a Pseudo‐Natural‐Product Autophagy Inhibitor

Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation

Inducin Triggers LC3‐Lipidation and ESCRT‐Mediated Lysosomal Membrane Repair

Human Leukemia Xenotransplantation Into Zebrafish Embryos as An In Vivo Assay for Chemotherapy Drug Response

Abstract 4251: Evaluating novel targeted therapeutic agents in T-cell acute lymphoblastic leukemia using a zebrafish xenotransplantation model

Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation

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