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Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis

Current medicinal chemistry, 1999-07, Vol.6 (7), p.561

1999

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Metabolism and action of amino acid analog anti-cancer agents

Pharmacology & therapeutics (Oxford), 1990, Vol.46 (2), p.243-271

1990

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Carbocyclic Analogues of the Potent Cytidine Deaminase Inhibitor 1-(β-d-Ribofuranosyl)-1,2-dihydropyrimidin-2-one (Zebularine)

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2572-2578

1998

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Site of action of two novel pyrimidine biosynthesis inhibitors accurately predicted by the COMPARE program

Biochemical pharmacology, 1995-03, Vol.49 (7), p.947-954

1995

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Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase

International journal of cancer, 1994-03, Vol.56 (6), p.892-899

1994

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Synthesis of thiazole-4-carboxamide adenine dinucleotide. A powerful inhibitor of IMP dehydrogenase

Journal of medicinal chemistry, 1983-06, Vol.26 (6), p.922-925

1983

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Initial studies on the cellular pharmacology of 2',3'-dideoxyadenosine, an inhibitor of HTLV-III infectivity

Biochemical pharmacology, 1987-06, Vol.36 (11), p.1765-1768

1987

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Resistance to cyclopentenylcytosine in murine leukemia L1210 cells

Cancer research (Chicago, Ill.), 1993-12, Vol.53 (23), p.5714-5720

1993

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Cellular pharmacology of cyclopentenyl cytosine in Molt-4 lymphoblasts

Cancer research (Chicago, Ill.), 1991-07, Vol.51 (14), p.3733-3740

1991

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Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogs. Synthesis, structure, and interactions with IMP dehydrogenase

Journal of medicinal chemistry, 1985-01, Vol.28 (1), p.99-105

1985

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Thiazole-4-carboxamide adenine dinucleotide (TAD). Analogs stable to phosphodiesterase hydrolysis

Journal of medicinal chemistry, 1986-09, Vol.29 (9), p.1726-1731

1986

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A straightforward radiometric technique for measuring IMP dehydrogenase

Analytical biochemistry, 1983-04, Vol.130 (2), p.339-345

1983

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Identification of the antimetabolite of L-alanosine, L-alanosyl-5-amino-4-imidazolecarboxylic acid ribonucleotide, in tumors and assessment of its inhibition of adenylosuccinate synthetase

Cancer research (Chicago, Ill.), 1980-12, Vol.40 (12), p.4390-4397

1980

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Mechanisms of sensitivity and resistance of murine tumors to 5-fluorouracil

Cancer research (Chicago, Ill.), 1980-05, Vol.40 (5), p.1431

1980

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Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides

The Journal of experimental medicine, 1988-09, Vol.168 (3), p.1111-1125

1988

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Biosynthetic Ganciclovir Triphosphate: Its Isolation and Characterization from Ganciclovir-Treated Herpes Simplex Thymidine Kinase-Transduced Murine Cells

Biochemical and biophysical research communications, 2001-11, Vol.289 (2), p.525-530

2001

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Enzymic Synthesis and Biochemical Activity of Various Indazole Adenine Dinucleotides

Bulletin of the Chemical Society of Japan, 1985-01, Vol.58 (1), p.309-315

1985

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Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid

Cancer research (Chicago, Ill.), 1981-03, Vol.41 (3), p.894-904

1981

Volltextzugriff (PDF)

Effects of Bone Marrow Stimulatory Cytokines on Human Immunodeficiency Virus Replication and the Antiviral Activity of Dideoxynucleosides in Cultures of Monocyte/Macrophages

Blood, 1992-08, Vol.80 (4), p.995-1003

1992

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Bleomycin-induced interstitial pneumonia in dogs

Thorax, 1971-11, Vol.26 (6), p.675-682

1971

Volltextzugriff (PDF)

Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin

Biochemical pharmacology, 1994-10, Vol.48 (7), p.1413-1419

1994

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Potent and selective anti-HTLV-IIILAV activity of 2′,3′-dideoxycytidinene, the 2′,3′-unsaturated derivative of 2′,3′-dideoxycytidine

Biochemical and biophysical research communications, 1986-10, Vol.140 (2), p.735-742

1986

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Initial studies on the cellular pharmacology of 2′,3′-dideoxycytidine, an inhibitor of HTLV-III infectivity

Biochemical pharmacology, 1986-07, Vol.35 (13), p.2065-2068

1986

Volltextzugriff (PDF)

Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate

Molecular pharmacology, 1990-02, Vol.37 (2), p.157-163

1990

Volltextzugriff (PDF)

Long-term association of N-(phosphonacetyl)-L-aspartate with bone

Cancer research (Chicago, Ill.), 1981-01, Vol.41 (1), p.150-156

1981

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Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis

Metabolism and action of amino acid analog anti-cancer agents

Carbocyclic Analogues of the Potent Cytidine Deaminase Inhibitor 1-(β-d-Ribofuranosyl)-1,2-dihydropyrimidin-2-one (Zebularine)

Site of action of two novel pyrimidine biosynthesis inhibitors accurately predicted by the COMPARE program

Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase

Synthesis of thiazole-4-carboxamide adenine dinucleotide. A powerful inhibitor of IMP dehydrogenase

Initial studies on the cellular pharmacology of 2',3'-dideoxyadenosine, an inhibitor of HTLV-III infectivity

Resistance to cyclopentenylcytosine in murine leukemia L1210 cells

Cellular pharmacology of cyclopentenyl cytosine in Molt-4 lymphoblasts

Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogs. Synthesis, structure, and interactions with IMP dehydrogenase

Thiazole-4-carboxamide adenine dinucleotide (TAD). Analogs stable to phosphodiesterase hydrolysis

A straightforward radiometric technique for measuring IMP dehydrogenase

Identification of the antimetabolite of L-alanosine, L-alanosyl-5-amino-4-imidazolecarboxylic acid ribonucleotide, in tumors and assessment of its inhibition of adenylosuccinate synthetase

Mechanisms of sensitivity and resistance of murine tumors to 5-fluorouracil

Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides

Biosynthetic Ganciclovir Triphosphate: Its Isolation and Characterization from Ganciclovir-Treated Herpes Simplex Thymidine Kinase-Transduced Murine Cells

Enzymic Synthesis and Biochemical Activity of Various Indazole Adenine Dinucleotides

Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid

Effects of Bone Marrow Stimulatory Cytokines on Human Immunodeficiency Virus Replication and the Antiviral Activity of Dideoxynucleosides in Cultures of Monocyte/Macrophages

Bleomycin-induced interstitial pneumonia in dogs

Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin

Potent and selective anti-HTLV-IIILAV activity of 2′,3′-dideoxycytidinene, the 2′,3′-unsaturated derivative of 2′,3′-dideoxycytidine

Initial studies on the cellular pharmacology of 2′,3′-dideoxycytidine, an inhibitor of HTLV-III infectivity

Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate

Long-term association of N-(phosphonacetyl)-L-aspartate with bone

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