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Assessment of climate change effects on vegetation and river hydrology in a semi-arid river basin

PloS one, 2022-08, Vol.17 (8), p.e0271991-e0271991

2022

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MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road

Nature reviews. Cancer, 2015-10, Vol.15 (10), p.577

2015

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ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

Pharmacology & therapeutics (Oxford), 2018-07, Vol.187, p.45-60

2018

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FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

Cell stem cell, 2013-09, Vol.13 (3), p.351-359

2013

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

Molecular cell, 2020-01, Vol.77 (2), p.228-240.e7

2020

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Maternal DNA Methylation Regulates Early Trophoblast Development

Developmental cell, 2016-01, Vol.36 (2), p.152-163

2016

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Accelerated mass loss of Himalayan glaciers since the Little Ice Age

Scientific reports, 2021-12, Vol.11 (1), p.24284-24284, Article 24284

2021

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De-regulated FGF receptors as therapeutic targets in cancer

Pharmacology & therapeutics (Oxford), 2010-01, Vol.125 (1), p.105-117

2010

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CDK1, the Other ‘Master Regulator’ of Autophagy

Trends in cell biology, 2021-02, Vol.31 (2), p.95-107

2021

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Targeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors

Cells (Basel, Switzerland), 2018-08, Vol.7 (9), p.115

2018

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RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence

Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6284), p.453-459

2016

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The empirical basis for modelling glacial erosion rates

Nature communications, 2020-02, Vol.11 (1), p.759-759, Article 759

2020

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ERK1/2 signalling protects against apoptosis following endoplasmic reticulum stress but cannot provide long-term protection against BAX/BAK-independent cell death

PloS one, 2017-09, Vol.12 (9), p.e0184907-e0184907

2017

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The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance

Biochemical journal, 2013-03, Vol.450 (2), p.285-294

2013

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Glacier change and glacial lake outburst flood risk in the Bolivian Andes

The cryosphere, 2016-10, Vol.10 (5), p.2399-2413

2016

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Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors

Nature communications, 2019-11, Vol.10 (1), p.5167-19, Article 5167

2019

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ERK5 and its role in tumour development

Biochemical Society transactions, 2012-02, Vol.40 (1), p.251

2012

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Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors

Nature communications, 2020-03, Vol.11 (1), p.1383-1383, Article 1383

2020

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Shaking up Assumptions: Earthquakes Have Rarely Triggered Andean Glacier Lake Outburst Floods

Geophysical research letters, 2024-04, Vol.51 (7), p.n/a

2024

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Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation

Journal of cell science, 2014-02, Vol.127 (Pt 4), p.788

2014

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Activation of the ERK1/2 Signaling Pathway Promotes Phosphorylation and Proteasome-dependent Degradation of the BH3-only Protein, Bim

The Journal of biological chemistry, 2003-05, Vol.278 (21), p.18811-18816

2003

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Modelling climate change impact on water resources of the Upper Indus Basin

Journal of water and climate change, 2022-02, Vol.13 (2), p.482-504

2022

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ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled?

Frontiers in cell and developmental biology, 2022-07, Vol.10, p.839997-839997

2022

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Intrinsic and acquired resistance to MEK1/2 inhibitors in cancer

Biochemical Society transactions, 2014-08, Vol.42 (4), p.776

2014

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The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

Biochimica et biophysica acta, 2014-10, Vol.1843 (10), p.2150-2163

2014

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Assessment of climate change effects on vegetation and river hydrology in a semi-arid river basin

MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

Maternal DNA Methylation Regulates Early Trophoblast Development

Accelerated mass loss of Himalayan glaciers since the Little Ice Age

De-regulated FGF receptors as therapeutic targets in cancer

CDK1, the Other ‘Master Regulator’ of Autophagy

Targeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors

RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence

The empirical basis for modelling glacial erosion rates

ERK1/2 signalling protects against apoptosis following endoplasmic reticulum stress but cannot provide long-term protection against BAX/BAK-independent cell death

The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance

Glacier change and glacial lake outburst flood risk in the Bolivian Andes

Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors

ERK5 and its role in tumour development

Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors

Shaking up Assumptions: Earthquakes Have Rarely Triggered Andean Glacier Lake Outburst Floods

Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation

Activation of the ERK1/2 Signaling Pathway Promotes Phosphorylation and Proteasome-dependent Degradation of the BH3-only Protein, Bim

Modelling climate change impact on water resources of the Upper Indus Basin

ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled?

Intrinsic and acquired resistance to MEK1/2 inhibitors in cancer

The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

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