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Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase

Journal of medicinal chemistry, 2004-04, Vol.47 (9), p.2283-2295

2004

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Synthesis of AZT 5‘-Triphosphate Mimics and Their Inhibitory Effects on HIV-1 Reverse Transcriptase

Journal of medicinal chemistry, 2004-12, Vol.47 (27), p.6902-6913

2004

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Synthesis and Evaluation of S-Acyl-2-thioethyl Esters of Modified Nucleoside 5‘-Monophosphates as Inhibitors of Hepatitis C Virus RNA Replication

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.1199-1210

2005

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Synthesis of 2‘,3‘-Dideoxynucleoside 5‘-α-P-Borano-β,γ-(difluoromethylene)triphosphates and Their Inhibition of HIV-1 Reverse Transcriptase

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2695-2700

2005

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2‘-O-[2-[2-(N,N-Dimethylamino)ethoxy]ethyl] Modified Oligonucleotides: Symbiosis of Charge Interaction Factors and Stereoelectronic Effects

Organic letters, 2003-06, Vol.5 (12), p.2017-2020

2003

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Structure−Activity Relationship of Heterobase-Modified 2‘-C-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication

Journal of medicinal chemistry, 2004-10, Vol.47 (21), p.5284-5297

2004

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Methodologies for Generating Solution-Phase Combinatorial Libraries

Chemical reviews, 2000-09, Vol.100 (9), p.3311-3340

2000

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X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution

Biopolymers, 1998, Vol.48 (4), p.234-252

1998

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Structure−Activity Relationships of Novel 2-Substituted Quinazoline Antibacterial Agents

Journal of medicinal chemistry, 1999-11, Vol.42 (22), p.4705-4713

1999

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2′,3′-Dideoxynucleoside 5′-β,γ-(Difluoromethylene) Triphosphates With α-P-Thio or α-P-Seleno Modifications: Synthesis and Their Inhibition of HIV-1 Reverse Transcriptase

Nucleosides, nucleotides & nucleic acids, 2005-09, Vol.24 (10-12), p.1651-1664

2005

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Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR

Journal of computer-aided molecular design, 2000-08, Vol.14 (6), p.593-610

2000

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Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Journal of medicinal chemistry, 1993-04, Vol.36 (7), p.831-841

1993

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Electrophilic Fluorination of 5-(Cyanomethyl)imidazole-4-carboxylate Nucleosides: Facile Entry to 3-Fluoro-3-deazaguanosine Analogues

Synlett, 2005-06, Vol.2005 (10), p.1586-1590

2005

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In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells

Nucleic acids research, 1997-08, Vol.25 (16), p.3290

1997

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Structural Origins of the Exonuclease Resistance of a Zwitterionic RNA

Proceedings of the National Academy of Sciences - PNAS, 1999-12, Vol.96 (25), p.14240-14245

1999

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Novel functionalization of the sugar moiety of nucleic acids for multiple labeling in the minor groove

Tetrahedron letters, 1991-12, Vol.32 (49), p.7171-7174

1991

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2‘-O-Aminopropyl Ribonucleotides: A Zwitterionic Modification That Enhances the Exonuclease Resistance and Biological Activity of Antisense Oligonucleotides

Journal of medicinal chemistry, 1996-12, Vol.39 (26), p.5100-5109

1996

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Crystal structure and improved antisense properties of 2'- O -(2-methoxyethyl)-RNA

Nature structural biology, 1999-06, Vol.6 (6), p.535-539

1999

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Making Drugs Out of Oligonucleotides: A Brief Review and Perspective

Nucleosides & nucleotides, 1999-06, Vol.18 (6-7), p.1141-1162

Cook, P. Dan

1999

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2;-O-[2-[2-(N,N-Dimethylamino)ethoxy]ethyl] Modified Antisense Oligonucleotides: Symbiosis of Charge Interaction Factors and Stereoelectronic Effects

Organic letters, 2016-04, Vol.5 (12)

2016

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N-(2-Cyanoethoxycarbonyloxy)succinimide: A New Reagent for Protection of Amino Groups in Oligonucleotides

Journal of organic chemistry, 1999-08, Vol.64 (17), p.6468-6472

1999

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Electrochemical Detection of Surface Hybridization of Oligodeoxynucleotides Bearing Anthraquinone Tags at Gold Electrodes

Electroanalysis (New York, N.Y.), 2000-08, Vol.12 (12), p.889-894

2000

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Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences

Journal of the American Chemical Society, 1992-05, Vol.114 (10), p.4006-4007

1992

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Synthesis and Electrochemistry of Anthraquinone−Oligodeoxynucleotide Conjugates

Bioconjugate chemistry, 1999-03, Vol.10 (2), p.261-270

1999

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Intermolecular radical CC bond formation: Synthesis of a novel dinucleoside linker for non-anionic antisense oligonucleosides

Tetrahedron letters, 1992-05, Vol.33 (19), p.2645-2648

1992

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Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase

Synthesis of AZT 5‘-Triphosphate Mimics and Their Inhibitory Effects on HIV-1 Reverse Transcriptase

Synthesis and Evaluation of S-Acyl-2-thioethyl Esters of Modified Nucleoside 5‘-Monophosphates as Inhibitors of Hepatitis C Virus RNA Replication

Synthesis of 2‘,3‘-Dideoxynucleoside 5‘-α-P-Borano-β,γ-(difluoromethylene)triphosphates and Their Inhibition of HIV-1 Reverse Transcriptase

2‘-O-[2-[2-(N,N-Dimethylamino)ethoxy]ethyl] Modified Oligonucleotides: Symbiosis of Charge Interaction Factors and Stereoelectronic Effects

Structure−Activity Relationship of Heterobase-Modified 2‘-C-Methyl Ribonucleosides as Inhibitors of Hepatitis C Virus RNA Replication

Methodologies for Generating Solution-Phase Combinatorial Libraries

X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution

Structure−Activity Relationships of Novel 2-Substituted Quinazoline Antibacterial Agents

2′,3′-Dideoxynucleoside 5′-β,γ-(Difluoromethylene) Triphosphates With α-P-Thio or α-P-Seleno Modifications: Synthesis and Their Inhibition of HIV-1 Reverse Transcriptase

Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Electrophilic Fluorination of 5-(Cyanomethyl)imidazole-4-carboxylate Nucleosides: Facile Entry to 3-Fluoro-3-deazaguanosine Analogues

In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells

Structural Origins of the Exonuclease Resistance of a Zwitterionic RNA

Novel functionalization of the sugar moiety of nucleic acids for multiple labeling in the minor groove

2‘-O-Aminopropyl Ribonucleotides: A Zwitterionic Modification That Enhances the Exonuclease Resistance and Biological Activity of Antisense Oligonucleotides

Crystal structure and improved antisense properties of 2'- O -(2-methoxyethyl)-RNA

Making Drugs Out of Oligonucleotides: A Brief Review and Perspective

2;-O-[2-[2-(N,N-Dimethylamino)ethoxy]ethyl] Modified Antisense Oligonucleotides: Symbiosis of Charge Interaction Factors and Stereoelectronic Effects

N-(2-Cyanoethoxycarbonyloxy)succinimide: A New Reagent for Protection of Amino Groups in Oligonucleotides

Electrochemical Detection of Surface Hybridization of Oligodeoxynucleotides Bearing Anthraquinone Tags at Gold Electrodes

Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences

Synthesis and Electrochemistry of Anthraquinone−Oligodeoxynucleotide Conjugates

Intermolecular radical CC bond formation: Synthesis of a novel dinucleoside linker for non-anionic antisense oligonucleosides

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