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Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans

Drug metabolism and disposition, 2003-11, Vol.31 (11), p.1448

2003

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Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5

Drug metabolism and disposition, 2002-12, Vol.30 (12), p.1344

2002

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Daily peritoneal administration of sodium pyrophosphate in a dialysis solution prevents the development of vascular calcification in a mouse model of uraemia

Nephrology, dialysis, transplantation, 2011-10, Vol.26 (10), p.3349-3357

2011

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Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism

Drug metabolism and disposition, 2003-05, Vol.31 (5), p.652

2003

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Pharmacokinetics of celecoxib after oral administration in dogs and humans: effect of food and site of absorption

The Journal of pharmacology and experimental therapeutics, 2001-05, Vol.297 (2), p.638

2001

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Interconversion Pharmacokinetics of Eplerenone, a Selective Aldosterone Blocker, and its Lactone‐Ring Open Form

Journal of pharmaceutical sciences, 2002-06, Vol.91 (6), p.1383-1389

2002

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Atypical dose–route-dependent food effects of eplerenone in the dog: Presence of food effects following intravenous dosing and lack of food effects of following oral dosing

Journal of pharmaceutical sciences, 2002-03, Vol.91 (3), p.607-614

2002

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Absorption and disposition of a selective aldosterone receptor antagonist, eplerenone, in the dog

Pharmaceutical research, 2000-11, Vol.17 (11), p.1426-1431

2000

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Differential enantioselectivity and product-dependent activation and inhibition in metabolism of verapamil by human CYP3As

Drug metabolism and disposition, 2004-02, Vol.32 (2), p.186

2004

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Pharmacology of SC-52458, an Orally Active, Nonpeptide Angiotensin AT1 Receptor Antagonist

Journal of cardiovascular pharmacology, 1993-10, Vol.22 (4), p.677-677

1993

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Eplerenone: A Selective Aldosterone Receptor Antagonist (SARA)

Cardiovascular drug reviews, 2001-09, Vol.19 (3), p.185-200

2001

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Mechanism of compound- and species-specific food effects of structurally related antiarrhythmic drugs, disopyramide and bidisomide

Pharmaceutical research, 1998-03, Vol.15 (3), p.429-433

1998

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Mechanisms of food effects of structurally related antiarrhythmic drugs, disopyramide and bidisomide in the rat

Pharmaceutical research, 1997-08, Vol.14 (8), p.1030-1038

1997

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Effects of SC-56525, a Potent, Orally Active Renin Inhibitor, in Salt-Depleted and Renal Hypertensive Dogs

Hypertension (Dallas, Tex. 1979), 1995-07, Vol.26 (1), p.95-100

1995

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Species dependent esterase activities for hydrolysis of an anti-HIV prodrug glycovir and bioavailability of active SC-48334

Pharmaceutical research, 1995-08, Vol.12 (8), p.1158-1164

1995

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Effects of SC-52458, an Angiotensin AT 1 Receptor Antagonist, in the Dog

American journal of hypertension, 1997, Vol.10 (6), p.671-677

1997

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Effect of Salicylic Acid on the Plasma Protein Binding and Pharmacokinetics of Misoprostol Acid

Journal of pharmaceutical sciences, 1994-06, Vol.83 (6), p.883-886

1994

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Pharmacokinetics of a novel antiarrhythmic drug, actisomide

Pharmaceutical research, 1993-03, Vol.10 (3), p.427-433

1993

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Effects of SC-52458, an Angiotensin AT1 Receptor Antagonist, in the Dog

American journal of hypertension, 1997-06, Vol.10 (6), p.671-677

1997

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Absorption and disposition of a new antiarrhythmic agent bidisomide in man

Pharmaceutical research, 1993-11, Vol.10 (11), p.1675-1682

1993

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Difference in metabolic profile of potassium canrenoate and spironolactone in the rat: mutagenic metabolites unique to potassium canrenoate

Archives of toxicology, 1988-01, Vol.61 (3), p.201-212

1988

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Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat

International journal of pharmaceutics, 2007-07, Vol.339 (1), p.251-260

2007

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Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

The Journal of cell biology, 1997-08, Vol.138 (3), p.671-680

1997

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Nanosuspension Formulation of Itraconazole Eliminates the Negative Inotropic Effect of SPORANOX® in Dogs

Journal of medical toxicology, 2010-09, Vol.6 (3), p.331-336

2010

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Absorption, Metabolism, Distribution, and Excretion of Longer Acting rFVIII (BAX 855) Following Intravenous Administration to Rats

Blood, 2011-11, Vol.118 (21), p.4358-4358

2011

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Pharmacokinetics and metabolism of [14C]eplerenone after oral administration to humans

Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5

Daily peritoneal administration of sodium pyrophosphate in a dialysis solution prevents the development of vascular calcification in a mouse model of uraemia

Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism

Pharmacokinetics of celecoxib after oral administration in dogs and humans: effect of food and site of absorption

Interconversion Pharmacokinetics of Eplerenone, a Selective Aldosterone Blocker, and its Lactone‐Ring Open Form

Atypical dose–route-dependent food effects of eplerenone in the dog: Presence of food effects following intravenous dosing and lack of food effects of following oral dosing

Absorption and disposition of a selective aldosterone receptor antagonist, eplerenone, in the dog

Differential enantioselectivity and product-dependent activation and inhibition in metabolism of verapamil by human CYP3As

Pharmacology of SC-52458, an Orally Active, Nonpeptide Angiotensin AT1 Receptor Antagonist

Eplerenone: A Selective Aldosterone Receptor Antagonist (SARA)

Mechanism of compound- and species-specific food effects of structurally related antiarrhythmic drugs, disopyramide and bidisomide

Mechanisms of food effects of structurally related antiarrhythmic drugs, disopyramide and bidisomide in the rat

Effects of SC-56525, a Potent, Orally Active Renin Inhibitor, in Salt-Depleted and Renal Hypertensive Dogs

Species dependent esterase activities for hydrolysis of an anti-HIV prodrug glycovir and bioavailability of active SC-48334

Effects of SC-52458, an Angiotensin AT 1 Receptor Antagonist, in the Dog

Effect of Salicylic Acid on the Plasma Protein Binding and Pharmacokinetics of Misoprostol Acid

Pharmacokinetics of a novel antiarrhythmic drug, actisomide

Effects of SC-52458, an Angiotensin AT1 Receptor Antagonist, in the Dog

Absorption and disposition of a new antiarrhythmic agent bidisomide in man

Difference in metabolic profile of potassium canrenoate and spironolactone in the rat: mutagenic metabolites unique to potassium canrenoate

Itraconazole IV nanosuspension enhances efficacy through altered pharmacokinetics in the rat

Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

Nanosuspension Formulation of Itraconazole Eliminates the Negative Inotropic Effect of SPORANOX® in Dogs

Absorption, Metabolism, Distribution, and Excretion of Longer Acting rFVIII (BAX 855) Following Intravenous Administration to Rats

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