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Bifunctional Molecules beyond PROTACs

Journal of medicinal chemistry, 2020-03, Vol.63 (6), p.2802-2806

Conway, Stuart J

2020

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Small molecules as tools to study the chemical epigenetics of lysine acetylation

Current opinion in chemical biology, 2018-08, Vol.45, p.166-178

2018

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Celebrating the Medicinal Chemistry of Gunda Georg and Shaomeng Wang

Journal of medicinal chemistry, 2021-12, Vol.64 (24), p.17541-17544

2021

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Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria

Nature communications, 2019-07, Vol.10 (1), p.3430-11, Article 3430

2019

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NAADP Activates Two-Pore Channels on T Cell Cytolytic Granules to Stimulate Exocytosis and Killing

Current biology, 2012-12, Vol.22 (24), p.2331-2337

2012

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Clinical Advances of Hypoxia-Activated Prodrugs in Combination With Radiation Therapy

International journal of radiation oncology, biology, physics, 2017-08, Vol.98 (5), p.1183-1196

2017

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Two Color Imaging of Different Hypoxia Levels in Cancer Cells

Journal of the American Chemical Society, 2023-02, Vol.145 (4), p.2572-2583

2023

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3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands

Journal of medicinal chemistry, 2011-10, Vol.54 (19), p.6761-6770

2011

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Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

Journal of the American Chemical Society, 2014-07, Vol.136 (26), p.9308-9319

2014

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Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.9393-9413

2012

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Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Cell chemical biology, 2021-09, Vol.28 (9), p.1258-1270.e13

2021

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Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

ACS chemical biology, 2015-01, Vol.10 (1), p.22-39

2015

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Interaction of the Mechanosensitive Channel, MscS, with the Membrane Bilayer through Lipid Intercalation into Grooves and Pockets

Journal of molecular biology, 2019-08, Vol.431 (17), p.3339-3352

2019

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Disarming Gram-Negative Bacteria in the Fight Against Antimicrobial Resistance

ACS central science, 2023-12, Vol.9 (12), p.2179-2182

2023

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Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs

Nature protocols, 2016-04, Vol.11 (4), p.781-794

2016

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Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications

Nature chemistry, 2021-06, Vol.13 (6), p.540-548

2021

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Coupling Photoresponsive Transmembrane Ion Transport with Transition Metal Catalysis

Journal of the American Chemical Society, 2024-02, Vol.146 (7), p.4351-4356

2024

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The use of phosphate bioisosteres in medicinal chemistry and chemical biology

MedChemComm, 2012-07, Vol.3 (7), p.735-751

2012

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Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

Journal of medicinal chemistry, 2013-04, Vol.56 (8), p.3217-3227

2013

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Increasing Diversity in Admissions to Postgraduate Study

Journal of medicinal chemistry, 2022-04, Vol.65 (8), p.5867-5869

2022

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Chemical Epigenetics: The Impact of Chemical and Chemical Biology Techniques on Bromodomain Target Validation

Angewandte Chemie International Edition, 2019-12, Vol.58 (50), p.17930-17952

International ed. in English, 2019

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Laboratory and field investigations of particulate and carbon monoxide emissions from traditional and improved cookstoves

Atmospheric environment (1994), 2009-02, Vol.43 (6), p.1170-1181

2009

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Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.15801-15822

2023

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Epigenetics 2.0: Special Issue on EpigeneticsCall for Papers

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12129-12130

2020

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Small Molecule Ligands of the BET-like Bromodomain, Sm BRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.15801-15822

2023

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Bifunctional Molecules beyond PROTACs

Small molecules as tools to study the chemical epigenetics of lysine acetylation

Celebrating the Medicinal Chemistry of Gunda Georg and Shaomeng Wang

Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria

NAADP Activates Two-Pore Channels on T Cell Cytolytic Granules to Stimulate Exocytosis and Killing

Clinical Advances of Hypoxia-Activated Prodrugs in Combination With Radiation Therapy

Two Color Imaging of Different Hypoxia Levels in Cancer Cells

3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

Interaction of the Mechanosensitive Channel, MscS, with the Membrane Bilayer through Lipid Intercalation into Grooves and Pockets

Disarming Gram-Negative Bacteria in the Fight Against Antimicrobial Resistance

Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs

Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications

Coupling Photoresponsive Transmembrane Ion Transport with Transition Metal Catalysis

The use of phosphate bioisosteres in medicinal chemistry and chemical biology

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

Increasing Diversity in Admissions to Postgraduate Study

Chemical Epigenetics: The Impact of Chemical and Chemical Biology Techniques on Bromodomain Target Validation

Laboratory and field investigations of particulate and carbon monoxide emissions from traditional and improved cookstoves

Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development

Epigenetics 2.0: Special Issue on EpigeneticsCall for Papers

Small Molecule Ligands of the BET-like Bromodomain, Sm BRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development

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