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Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles

Journal of hepatology, 2016-03, Vol.64 (3), p.651-660

2016

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Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte‐Mediated Paracrine Mechanism

Hepatology communications, 2019-07, Vol.3 (7), p.987-1000

2019

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Characterization of IDN-6556 (3-[2-(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino]-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid): a liver-targeted caspase inhibitor

The Journal of pharmacology and experimental therapeutics, 2004-05, Vol.309 (2), p.634-640

2004

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Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo

Toxicological sciences, 2018-04, Vol.162 (2), p.396-405

2018

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Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse

Hepatology research, 2009-08, Vol.39 (8), p.805-813

2009

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Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil

Neuroscience letters, 1998-01, Vol.241 (2), p.95-98

1998

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Insulin-like Growth Factor-I: Potential for Treatment of Motor Neuronal Disorders

Experimental neurology, 1993-11, Vol.124 (1), p.73-88

1993

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Characterization of the caspase inhibitor IDN-1965 in a model of apoptosis-associated liver injury

The Journal of pharmacology and experimental therapeutics, 2001-05, Vol.297 (2), p.811

2001

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Phencyclidine-like effects of tetrahydroisoquinolines and related compounds

Journal of medicinal chemistry, 1989-06, Vol.32 (6), p.1242-1248

1989

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Preparation and opioid activity of analogs of the analgesic dipeptide 2,6-dimethyl-L-tyrosyl-N-(3-phenylpropyl)-D-alaninamide

Journal of medicinal chemistry, 1992-01, Vol.35 (2), p.223-233

1992

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Insulin-like growth factor-I prevents development of a vincristine neuropathy in mice

Brain research, 1997-11, Vol.774 (1), p.20-26

1997

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Classification and nomenclature of phencyclidine and sigma receptor sites

Trends in neurosciences (Regular ed.), 1987-11, Vol.10 (11), p.444-446

1987

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Insulin-like Growth Factor-1 (IGF-1) Improves both Neurological Motor and Cognitive Outcome Following Experimental Brain Injury

Experimental neurology, 1997-10, Vol.147 (2), p.418-427

1997

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Selective memory impairment by phencyclidine in rats

European journal of pharmacology, 1987-08, Vol.140 (1), p.69-73

1987

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Region‐Specific Targets of p42/p44MAPK Signaling in Rat Brain

Journal of neurochemistry, 1998-02, Vol.70 (2), p.558-571

1998

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Glycine modulation of the phencyclidine binding site in mammalian brain

Brain research, 1988-03, Vol.442 (2), p.396-398

1988

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Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity .sigma. receptor ligands. Identification of a new class of highly potent and selective .sigma. receptor probes

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.3100-3110

1990

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Increased Expression of IL-1β Converting Enzyme in Hippocampus after Ischemia: Selective Localization in Microglia

The Journal of neuroscience, 1996-07, Vol.16 (13), p.4146-4154

1996

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Emergencies in dermatology outpatient clinics: our experience in Spain

EJD. European journal of dermatology, 2012-05, Vol.22 (3), p.408-409

2012

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D-serine antagonized phencyclidine- and MK-801-induced stereotyped behavior and ataxia

Neuropharmacology, 1990-03, Vol.29 (3), p.291-293

Contreras, Patricia C.

1990

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874 IDN-6556, the first anti-apoptotic caspase inhibitor in clinical trials: tissue distribution and pharmacokinetics

Hepatology (Baltimore, Md.), 2003, Vol.38, p.580-581

2003

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On the 50th anniversary of Dale's law: multiple neurotransmitter neurons

Trends in pharmacological sciences (Regular ed.), 1985, Vol.6, p.305-308

1985

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871 IDN-6556, the first anti-apoptotic caspase inhibitor: preclinical efficacy and safety

Hepatology (Baltimore, Md.), 2003, Vol.38, p.579-579

2003

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Effects of sigma ligands on mouse cerebellar cyclic guanosine monophosphate (cGMP) levels in vivo: further evidence for a functional modulation ofN-methyl- d-aspartate (NMDA) receptor complex-mediated events by sigma ligands

Brain research, 1991-10, Vol.561 (1), p.43-50

1991

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Synthesis, configuration, and evaluation of two conformationally restrained analogs of phencyclidine

Journal of medicinal chemistry, 1988-08, Vol.31 (8), p.1571-1575

1988

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Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles

Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte‐Mediated Paracrine Mechanism

Characterization of IDN-6556 (3-[2-(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino]-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid): a liver-targeted caspase inhibitor

Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo

Matrix metalloproteinase inhibitor, CTS-1027, attenuates liver injury and fibrosis in the bile duct-ligated mouse

Differential patterns of regional c-Fos induction in the rat brain by amphetamine and the novel wakefulness-promoting agent modafinil

Insulin-like Growth Factor-I: Potential for Treatment of Motor Neuronal Disorders

Characterization of the caspase inhibitor IDN-1965 in a model of apoptosis-associated liver injury

Phencyclidine-like effects of tetrahydroisoquinolines and related compounds

Preparation and opioid activity of analogs of the analgesic dipeptide 2,6-dimethyl-L-tyrosyl-N-(3-phenylpropyl)-D-alaninamide

Insulin-like growth factor-I prevents development of a vincristine neuropathy in mice

Classification and nomenclature of phencyclidine and sigma receptor sites

Insulin-like Growth Factor-1 (IGF-1) Improves both Neurological Motor and Cognitive Outcome Following Experimental Brain Injury

Selective memory impairment by phencyclidine in rats

Region‐Specific Targets of p42/p44MAPK Signaling in Rat Brain

Glycine modulation of the phencyclidine binding site in mammalian brain

Synthesis and evaluation of N-substituted cis-N-methyl-2-(1-pyrrolidinyl)cyclohexylamines as high affinity .sigma. receptor ligands. Identification of a new class of highly potent and selective .sigma. receptor probes

Increased Expression of IL-1β Converting Enzyme in Hippocampus after Ischemia: Selective Localization in Microglia

Emergencies in dermatology outpatient clinics: our experience in Spain

D-serine antagonized phencyclidine- and MK-801-induced stereotyped behavior and ataxia

874 IDN-6556, the first anti-apoptotic caspase inhibitor in clinical trials: tissue distribution and pharmacokinetics

On the 50th anniversary of Dale's law: multiple neurotransmitter neurons

871 IDN-6556, the first anti-apoptotic caspase inhibitor: preclinical efficacy and safety

Effects of sigma ligands on mouse cerebellar cyclic guanosine monophosphate (cGMP) levels in vivo: further evidence for a functional modulation ofN-methyl- d-aspartate (NMDA) receptor complex-mediated events by sigma ligands

Synthesis, configuration, and evaluation of two conformationally restrained analogs of phencyclidine

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