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N -Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK

MedChemComm, 2018, Vol.9 (6), p.963-968

2018

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Moderately lipophilic 2-(Het)aryl-6-dithioacetals, 2-phenyl-1,4-benzodioxane-6-dithioacetals and 2-phenylbenzofuran-5-dithioacetals: Synthesis and primary evaluation as potential antidiabetic AMPK-activators

Bioorganic & medicinal chemistry, 2023-05, Vol.87, p.117303-117303, Article 117303

2023

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Chryso-lactams:Gold(I) derivatives of ampicillin with specific activity against Gram-positive pathogens

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (9), p.127098-127098, Article 127098

2020

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1,2,3-Triazole-gold(I)-triethylposphine derivatives active against resistant Gram-positive pathogens

Bioorganic & medicinal chemistry letters, 2021-05, Vol.40, p.127879-127879, Article 127879

2021

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4-Hydroxy- N -[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade

MedChemComm, 2017-09, Vol.8 (9), p.1850-1855

2017

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Use of Hindered Silyl Ethers as Protecting Groups for the Non-aldol Aldol Process

Organic letters, 2003-08, Vol.5 (17), p.3159-3161

2003

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Design, Synthesis, and Structure−Activity Relationships of a Series of 3-[2-(1-Benzylpiperidin-4-yl)ethylamino]pyridazine Derivatives as Acetylcholinesterase Inhibitors

Journal of medicinal chemistry, 2001-08, Vol.44 (17), p.2707-2718

2001

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Aminopyridazines as Acetylcholinesterase Inhibitors

Journal of medicinal chemistry, 1999-02, Vol.42 (4), p.730-741

1999

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Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

Antiviral research, 2017-08, Vol.144, p.330-339

2017

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Approved drugs screening against the nsP1 capping enzyme of Venezuelan equine encephalitis virus using an immuno-based assay

Antiviral research, 2019-03, Vol.163, p.59-69

2019

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Homo and Heterodimer Ligands: The Twin Drug Approach

Practice of Medicinal Chemistry, 2008, p.1-1

Wermuth Camille Georges

3rd Edition, 2008

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N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIKElectronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

2018-06

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N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK† †Electronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

MedChemComm, 2018-04, Vol.9 (6), p.963-968

2018

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4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascadeElectronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, biochemical protocols. See DOI: 10.1039/c7md00278e

2017-09

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4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade† †Electronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, biochemical protocols. See DOI: 10.1039/c7md00278e

MedChemComm, 2017-08, Vol.8 (9), p.1850-1855

2017

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Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors

Journal of computer-aided molecular design, 2001-05, Vol.15 (5), p.395-410

2001

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Use of Hindered Silyl Ethers as Protecting Groups for the Non-aldol Aldol Process

ChemInform, 2003-12, Vol.34 (51), p.no-no

2003

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ChemInform Abstract: Design, Synthesis, and Structure-Activity Relationships of a Series of 3-[2-(1-Benzylpiperidin-4-yl)ethylamino]pyridazine Derivatives as Acetylcholinesterase Inhibitors

ChemInform, 2001-12, Vol.32 (49), p.no-no

2001

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Chapter 18 - Homo and Heterodimer Ligands: the Twin Drug Approach

The Practice of Medicinal Chemistry, 2008, p.380-414

Third Edition, 2008

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16 - Identical and Non-Identical Twin Drugs

The Practice of Medicinal Chemistry, 2003, p.251-273

Second Edition, 2003

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A two-plasmid inducible CRISPR/Cas9 genome editing tool for Clostridium acetobutylicum

Journal of microbiological methods, 2017-09, Vol.140, p.5-11

2017

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Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma

The New England journal of medicine, 2022-01, Vol.386 (1), p.24-34

2022

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Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma

The New England journal of medicine, 2022-02, Vol.386 (5), p.449-462

2022

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Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis

Microbiome, 2021-09, Vol.9 (1), p.183-183, Article 183

2021

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N -Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK

Moderately lipophilic 2-(Het)aryl-6-dithioacetals, 2-phenyl-1,4-benzodioxane-6-dithioacetals and 2-phenylbenzofuran-5-dithioacetals: Synthesis and primary evaluation as potential antidiabetic AMPK-activators

Chryso-lactams:Gold(I) derivatives of ampicillin with specific activity against Gram-positive pathogens

1,2,3-Triazole-gold(I)-triethylposphine derivatives active against resistant Gram-positive pathogens

4-Hydroxy- N -[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade

Use of Hindered Silyl Ethers as Protecting Groups for the Non-aldol Aldol Process

Design, Synthesis, and Structure−Activity Relationships of a Series of 3-[2-(1-Benzylpiperidin-4-yl)ethylamino]pyridazine Derivatives as Acetylcholinesterase Inhibitors

Aminopyridazines as Acetylcholinesterase Inhibitors

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

Approved drugs screening against the nsP1 capping enzyme of Venezuelan equine encephalitis virus using an immuno-based assay

Homo and Heterodimer Ligands: The Twin Drug Approach

N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIKElectronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK† †Electronic supplementary information (ESI) available: Additional biochemical data, chemistry, NMR characterization of final compounds, and biochemical protocols. See DOI: 10.1039/c8md00068a

Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors

Use of Hindered Silyl Ethers as Protecting Groups for the Non-aldol Aldol Process

ChemInform Abstract: Design, Synthesis, and Structure-Activity Relationships of a Series of 3-[2-(1-Benzylpiperidin-4-yl)ethylamino]pyridazine Derivatives as Acetylcholinesterase Inhibitors

Chapter 18 - Homo and Heterodimer Ligands: the Twin Drug Approach

16 - Identical and Non-Identical Twin Drugs

A two-plasmid inducible CRISPR/Cas9 genome editing tool for Clostridium acetobutylicum

Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma

Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis

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