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Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition

Scientific reports, 2023-01, Vol.13 (1), p.1273-1273, Article 1273

2023

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The La and related RNA‐binding proteins (LARPs): structures, functions, and evolving perspectives

Wiley interdisciplinary reviews. RNA, 2017-11, Vol.8 (6), p.e1430-n/a

2017

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AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration

Nature communications, 2023-05, Vol.14 (1), p.2740-2740, Article 2740

2023

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Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1

Nucleic acids research, 2022-01, Vol.50 (1), p.522-535

2022

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LARP6C orchestrates posttranscriptional reprogramming of gene expression during hydration to promote pollen tube guidance

The Plant cell, 2021-08, Vol.33 (8), p.2637-2661

2021

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Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins

PloS one, 2017-10, Vol.12 (10), p.e0185899

2017

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The RNA-binding protein LARP4 regulates cancer cell migration and invasion

Cytoskeleton (Hoboken, N.J.), 2016-11, Vol.73 (11), p.680-690

2016

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Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response

Nature communications, 2016-10, Vol.7 (1), p.13187-11, Article 13187

2016

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La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability

Molecular and Cellular Biology, 2011-02, Vol.31 (3), p.542-556

2011

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A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation

Redox biology, 2021-10, Vol.46, p.102107, Article 102107

2021

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The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis

iScience, 2024-04, Vol.27 (4), p.109288-109288, Article 109288

2024

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Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A

PloS one, 2014-11, Vol.9 (11), p.e113281-e113281

2014

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Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein

Structure (London), 2008-06, Vol.16 (6), p.852-862

2008

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Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein

Nature structural & molecular biology, 2004-04, Vol.11 (4), p.323-329

2004

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Allosteric Regulation of the Soluble Epoxide Hydrolase by Nitro Fatty Acids: a Combined Experimental and Computational Approach

Journal of molecular biology, 2022-09, Vol.434 (17), p.167600-167600, Article 167600

2022

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LARP4A and LARP4B in cancer: The new kids on the block

The international journal of biochemistry & cell biology, 2023-08, Vol.161, p.106441-106441, Article 106441

2023

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The La-related proteins: structures and interactions of a versatile superfamily of RNA-binding proteins

RNA biology, 2021-02, Vol.18 (2), p.178-193

2021

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Mining the PDB for Tractable Cases Where X‑ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein–Protein Inhibitors: Two Test Cases Illustrated by IL1β-IL1R and p38α–TAB1 Complexes

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7559-7568

2020

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Structural dynamics in the La-module of La-related proteins

RNA biology, 2021-02, Vol.18 (2), p.194-206

2021

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Epidemiology and patterns of care of patients admitted to Italian Intensive Cardiac Care units: the BLITZ-3 registry

Journal of cardiovascular medicine (Hagerstown, Md.), 2010-06, Vol.11 (6), p.450-461

2010

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Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain

Protein expression and purification, 2019-01, Vol.153, p.105-113

2019

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Getting to the end of RNA: Structural analysis of protein recognition of 5′ and 3′ termini

Biochimica et biophysica acta, 2009-09, Vol.1789 (9), p.653-666

2009

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LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA

Nucleic acids research, 2019-05, Vol.47 (8), p.4272-4291

2019

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Structure and RNA Interactions of the N-Terminal RRM Domains of PTB

Structure (London), 2004-09, Vol.12 (9), p.1631-1643

2004

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Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1

Nature structural & molecular biology, 2013-10, Vol.20 (10), p.1182-1190

2013

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Metabolic rewiring in MYC-driven medulloblastoma by BET-bromodomain inhibition

The La and related RNA‐binding proteins (LARPs): structures, functions, and evolving perspectives

AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration

Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1

LARP6C orchestrates posttranscriptional reprogramming of gene expression during hydration to promote pollen tube guidance

Analysis of the interaction of Plexin-B1 and Plexin-B2 with Rnd family proteins

The RNA-binding protein LARP4 regulates cancer cell migration and invasion

Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response

La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability

A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation

The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis

Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A

Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein

Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein

Allosteric Regulation of the Soluble Epoxide Hydrolase by Nitro Fatty Acids: a Combined Experimental and Computational Approach

LARP4A and LARP4B in cancer: The new kids on the block

The La-related proteins: structures and interactions of a versatile superfamily of RNA-binding proteins

Mining the PDB for Tractable Cases Where X‑ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein–Protein Inhibitors: Two Test Cases Illustrated by IL1β-IL1R and p38α–TAB1 Complexes

Structural dynamics in the La-module of La-related proteins

Epidemiology and patterns of care of patients admitted to Italian Intensive Cardiac Care units: the BLITZ-3 registry

Expression, purification, and characterisation of human soluble Epoxide Hydrolase (hsEH) and of its functional C-terminal domain

Getting to the end of RNA: Structural analysis of protein recognition of 5′ and 3′ termini

LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA

Structure and RNA Interactions of the N-Terminal RRM Domains of PTB

Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1

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