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BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors

Frontiers in oncology, 2022-04, Vol.12, p.766794-766794

2022

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Signal Transducer and Activator of Transcription 5a Mediates Mammary Ductal Branching and Proliferation in the Nulliparous Mouse

Endocrinology (Philadelphia), 2010-06, Vol.151 (6), p.2876-2885

2010

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Therapeutic potential of targeting mixed lineage kinases in cancer and inflammation

Pharmacology & therapeutics (Oxford), 2020-03, Vol.207, p.107457, Article 107457

2020

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Estrogen and Progesterone are Critical Regulators of Stat5a Expression in the Mouse Mammary Gland

Endocrinology (Philadelphia), 2008-01, Vol.149 (1), p.329-338

2008

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The scaffold protein MEK Partner 1 is required for the survival of estrogen receptor positive breast cancer cells

Cell communication and signaling, 2012-07, Vol.10 (1), p.18-18

2012

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Functional ablation of pRb activates Cdk2 and causes antiestrogen resistance in human breast cancer cells

PloS one, 2007-12, Vol.2 (12), p.e1256-e1256

2007

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Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis

Oncotarget, 2013-08, Vol.4 (8), p.1158-1171

2013

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c-Myc Suppresses p21WAF1/CIP1 Expression during Estrogen Signaling and Antiestrogen Resistance in Human Breast Cancer Cells

The Journal of biological chemistry, 2005-05, Vol.280 (18), p.17617-17625

2005

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Progesterone receptor A-regulated gene expression in mammary organoid cultures

The Journal of steroid biochemistry and molecular biology, 2009-07, Vol.115 (3), p.161-172

2009

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Hsp90/p50cdc37 Is Required for Mixed-lineage Kinase (MLK) 3 Signaling

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.19457-19463

2004

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The Cyclin-dependent Kinase Inhibitor p21WAF1/Cip1 Is an Antiestrogen-regulated Inhibitor of Cdk4 in Human Breast Cancer Cells

The Journal of biological chemistry, 2002-02, Vol.277 (7), p.5145-5152

2002

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Estrogen increases brain expression of the mRNA encoding transthyretin, an amyloid beta scavenger protein

Journal of Alzheimer's disease, 2004-08, Vol.6 (4), p.413

2004

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Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling

Cancer research (Chicago, Ill.), 2002-07, Vol.62 (14), p.3985-3991

2002

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Abstract 2374: Mixed-Lineage Kinase 3 signals through the FRA1-MMP1 axis to drive triple-negative breast cancer invasion and transendothelial migration

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2374-2374

2017

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Reversal of an antiestrogen-mediated cell cycle arrest of MCF-7 cells by viral tumor antigens requires the retinoblastoma protein-binding domain

Oncogene, 2000-09, Vol.19 (41), p.4746-4753

2000

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Inhibition of MP1 expression induces apoptosis of MCF‐7 breast cancer cells

The FASEB journal, 2011-04, Vol.25, p.658.7-658.7

2011

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Abstract 2807: Inhibition of mixed lineage kinase activity results in G2/M arrest and apoptosis in ER-positive breast cancer cells

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.2807-2807

2012

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Expression of an estrogen receptor variant lacking exon 3 in derivatives of MCF-7 cells with acquired estrogen independence or tamoxifen resistance

Journal of molecular endocrinology, 2004-06, Vol.32 (3), p.935-945

2004

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c-Myc Suppresses p21 super(WAF1/CIP1) Expression during Estrogen Signaling and Antiestrogen Resistance in Human Breast Cancer Cells

The Journal of biological chemistry, 2005-05, Vol.280 (18), p.17617-17625

2005

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Independent regulation of thymidine kinase mRNA and enzyme levels in serum-stimulated cells

The Journal of biological chemistry, 1990-04, Vol.265 (12), p.6954-6960

1990

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Identification of a G1-S-phase-regulated region in the human thymidine kinase gene promoter

Molecular and Cellular Biology, 1990-07, Vol.10 (7), p.3834-3837

1990

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Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites

Journal of Virology, 1996-09, Vol.70 (9), p.6304-6313

1996

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Regulation of the cellular thymidine kinase gene promoter in simian virus 40-infected cells

Journal of Virology, 1993-08, Vol.67 (8), p.4964-4971

1993

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Phenotypic conversion of TK-deficient cells following electroporation of functional TK enzyme

Experimental cell research, 1992, Vol.198 (1), p.36-42

1992

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Role of plasmid-coded RNA and ribonuclease III in plasmid DNA replication

Cell, 1979-09, Vol.18 (1), p.61-71

1979

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BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors

Signal Transducer and Activator of Transcription 5a Mediates Mammary Ductal Branching and Proliferation in the Nulliparous Mouse

Therapeutic potential of targeting mixed lineage kinases in cancer and inflammation

Estrogen and Progesterone are Critical Regulators of Stat5a Expression in the Mouse Mammary Gland

The scaffold protein MEK Partner 1 is required for the survival of estrogen receptor positive breast cancer cells

Functional ablation of pRb activates Cdk2 and causes antiestrogen resistance in human breast cancer cells

Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis

c-Myc Suppresses p21WAF1/CIP1 Expression during Estrogen Signaling and Antiestrogen Resistance in Human Breast Cancer Cells

Progesterone receptor A-regulated gene expression in mammary organoid cultures

Hsp90/p50cdc37 Is Required for Mixed-lineage Kinase (MLK) 3 Signaling

The Cyclin-dependent Kinase Inhibitor p21WAF1/Cip1 Is an Antiestrogen-regulated Inhibitor of Cdk4 in Human Breast Cancer Cells

Estrogen increases brain expression of the mRNA encoding transthyretin, an amyloid beta scavenger protein

Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling

Abstract 2374: Mixed-Lineage Kinase 3 signals through the FRA1-MMP1 axis to drive triple-negative breast cancer invasion and transendothelial migration

Reversal of an antiestrogen-mediated cell cycle arrest of MCF-7 cells by viral tumor antigens requires the retinoblastoma protein-binding domain

Inhibition of MP1 expression induces apoptosis of MCF‐7 breast cancer cells

Abstract 2807: Inhibition of mixed lineage kinase activity results in G2/M arrest and apoptosis in ER-positive breast cancer cells

Expression of an estrogen receptor variant lacking exon 3 in derivatives of MCF-7 cells with acquired estrogen independence or tamoxifen resistance

c-Myc Suppresses p21 super(WAF1/CIP1) Expression during Estrogen Signaling and Antiestrogen Resistance in Human Breast Cancer Cells

Independent regulation of thymidine kinase mRNA and enzyme levels in serum-stimulated cells

Identification of a G1-S-phase-regulated region in the human thymidine kinase gene promoter

Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites

Regulation of the cellular thymidine kinase gene promoter in simian virus 40-infected cells

Phenotypic conversion of TK-deficient cells following electroporation of functional TK enzyme

Role of plasmid-coded RNA and ribonuclease III in plasmid DNA replication

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