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Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma

The New England journal of medicine, 2021-02, Vol.384 (8), p.705-716

2021

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Metabolism of bupropion by carbonyl reductases in liver and intestine

Drug metabolism and disposition, 2015-07, Vol.43 (7), p.1019-1027

2015

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CC-99677, a novel, oral, selective covalent MK2 inhibitor, sustainably reduces pro-inflammatory cytokine production

Arthritis research & therapy, 2022-08, Vol.24 (1), p.1-15, Article 199

2022

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Phase Ib Study of the Histone Deacetylase 6 Inhibitor Citarinostat in Combination With Paclitaxel in Patients With Advanced Solid Tumors

Frontiers in oncology, 2022-01, Vol.11, p.786120-786120

2022

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Characterizing the exposure–response relationship of idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma

CPT: pharmacometrics and systems pharmacology, 2023-11, Vol.12 (11), p.1687-1697

2023

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Discovery of CC-99677, a selective targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune disorders

Translational research : the journal of laboratory and clinical medicine, 2022-11, Vol.249, p.49-73

2022

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Trastuzumab resistance induces EMT to transform HER2(+) PTEN(-) to a triple negative breast cancer that requires unique treatment options

Scientific reports, 2015-11, Vol.5 (1), p.15821-15821, Article 15821

2015

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Trastuzumab resistance induces EMT to transform HER2+ PTEN− to a triple negative breast cancer that requires unique treatment options

Scientific reports, 2015-12, Vol.5 (1)

2015

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A novel Bayesian generative approach for estimating tumor dynamics from published studies

CPT: pharmacometrics and systems pharmacology, 2024-08, Vol.13 (8), p.1341-1353

2024

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Pharmacokinetics and Pharmacogenomics of Bupropion in Three Different Formulations with Different Release Kinetics in Healthy Human Volunteers

The AAPS journal, 2017-09, Vol.19 (5), p.1513-1522

2017

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Xaluritamig, a STEAP1 × CD3 XmAb 2+1 Immune Therapy for Metastatic Castration-Resistant Prostate Cancer: Results from Dose Exploration in a First-in-Human Study

Cancer discovery, 2024-01, Vol.14 (1), p.76-89

2024

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Sotatercept Safety and Effects on Hemoglobin, Bone, and Vascular Calcification

Kidney international reports, 2019-11, Vol.4 (11), p.1585-1597

2019

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The Molecular Chaperone Hsp70 Activates Protein Phosphatase 5 (PP5) by Binding the Tetratricopeptide Repeat (TPR) Domain

The Journal of biological chemistry, 2014-01, Vol.289 (5), p.2908-2917

2014

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Population Pharmacokinetics of Lenalidomide in Healthy Volunteers and Patients With Hematologic Malignancies

Clinical pharmacology in drug development, 2018-06, Vol.7 (5), p.465-473

2018

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Modeling and simulation of the endogenous CYP3A induction marker 4β-hydroxycholesterol during enasidenib treatment

Clinical pharmacology: advances and applications, 2019-01, Vol.11, p.39-50

2019

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Identification of non-reported bupropion metabolites in human plasma

Biopharmaceutics & drug disposition, 2016-12, Vol.37 (9), p.550-560

2016

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A Mechanistic Physiologically‐Based Pharmacokinetic Platform Model to Guide Adult and Pediatric Intravenous and Subcutaneous Dosing for Bispecific T Cell Engagers

Clinical pharmacology and therapeutics, 2024-03, Vol.115 (3), p.457-467

2024

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Future Opportunities in Drug Development: American Society for Clinical Pharmacology and Therapeutics Pharmacometrics and Pharmacokinetics Community Vision

Clinical pharmacology and therapeutics, 2023-09, Vol.114 (3), p.507-510

2023

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Intracellular dissociation of a polymer coating from nanoparticles

Nano research, 2012-11, Vol.5 (11), p.815-825

2012

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Analogues of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, As Anti-Cancer Agents

ACS medicinal chemistry letters, 2013-11, Vol.4 (11), p.1042-1047

2013

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Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer

Oncotarget, 2016-08, Vol.7 (32), p.51408-51422

2016

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A phase 1b study of the safety, pharmacokinetics, and preliminary antitumor activity of citarinostat (ACY-241) in combination with paclitaxel (Pac) in patients (pts) with advanced solid tumors (AST)

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.2547-2547

2018

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Idecabtagene vicleucel (ide-cel; bb2121), a BCMA-targeted CAR T-cell therapy, in patients with relapsed and refractory multiple myeloma (RRMM): Initial KarMMa results

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.8503-8503

2020

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Modeling and simulation of the endogenous CYP3A induction marker 4[beta]-hydroxycholesterol during enasidenib treatment

Clinical pharmacology: advances and applications, 2019-02, Vol.11, p.39

2019

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Abstract 218: MEOX-1 as a novel cancer stem cell target for treatment of trastuzumab-resistant Her2+ breast cancers

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.218-218

2014

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Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma

Metabolism of bupropion by carbonyl reductases in liver and intestine

CC-99677, a novel, oral, selective covalent MK2 inhibitor, sustainably reduces pro-inflammatory cytokine production

Phase Ib Study of the Histone Deacetylase 6 Inhibitor Citarinostat in Combination With Paclitaxel in Patients With Advanced Solid Tumors

Characterizing the exposure–response relationship of idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma

Discovery of CC-99677, a selective targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune disorders

Trastuzumab resistance induces EMT to transform HER2(+) PTEN(-) to a triple negative breast cancer that requires unique treatment options

Trastuzumab resistance induces EMT to transform HER2+ PTEN− to a triple negative breast cancer that requires unique treatment options

A novel Bayesian generative approach for estimating tumor dynamics from published studies

Pharmacokinetics and Pharmacogenomics of Bupropion in Three Different Formulations with Different Release Kinetics in Healthy Human Volunteers

Xaluritamig, a STEAP1 × CD3 XmAb 2+1 Immune Therapy for Metastatic Castration-Resistant Prostate Cancer: Results from Dose Exploration in a First-in-Human Study

Sotatercept Safety and Effects on Hemoglobin, Bone, and Vascular Calcification

The Molecular Chaperone Hsp70 Activates Protein Phosphatase 5 (PP5) by Binding the Tetratricopeptide Repeat (TPR) Domain

Population Pharmacokinetics of Lenalidomide in Healthy Volunteers and Patients With Hematologic Malignancies

Modeling and simulation of the endogenous CYP3A induction marker 4β-hydroxycholesterol during enasidenib treatment

Identification of non-reported bupropion metabolites in human plasma

A Mechanistic Physiologically‐Based Pharmacokinetic Platform Model to Guide Adult and Pediatric Intravenous and Subcutaneous Dosing for Bispecific T Cell Engagers

Future Opportunities in Drug Development: American Society for Clinical Pharmacology and Therapeutics Pharmacometrics and Pharmacokinetics Community Vision

Intracellular dissociation of a polymer coating from nanoparticles

Analogues of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, As Anti-Cancer Agents

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer

A phase 1b study of the safety, pharmacokinetics, and preliminary antitumor activity of citarinostat (ACY-241) in combination with paclitaxel (Pac) in patients (pts) with advanced solid tumors (AST)

Idecabtagene vicleucel (ide-cel; bb2121), a BCMA-targeted CAR T-cell therapy, in patients with relapsed and refractory multiple myeloma (RRMM): Initial KarMMa results

Modeling and simulation of the endogenous CYP3A induction marker 4[beta]-hydroxycholesterol during enasidenib treatment

Abstract 218: MEOX-1 as a novel cancer stem cell target for treatment of trastuzumab-resistant Her2+ breast cancers

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