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Metabotropic glutamate receptors: From the workbench to the bedside

Neuropharmacology, 2011-06, Vol.60 (7), p.1017-1041

2011

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Selective potentiation of the metabotropic glutamate receptor subtype 2 blocks phencyclidine-induced hyperlocomotion and brain activation

Neuroscience, 2010-06, Vol.168 (1), p.209-218

2010

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Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function

Neuroscience, 1999-09, Vol.94 (1), p.185-192

1999

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Roles of the M4 acetylcholine receptor in the basal ganglia and the treatment of movement disorders

Movement disorders, 2019-08, Vol.34 (8), p.1089-1099

2019

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Synthesis and biological characterization of a series of novel diaryl amide M1 antagonists

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (22), p.6923-6928

2012

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Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition

Nature neuroscience, 1998-07, Vol.1 (3), p.185-191

1998

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Anticholinergic drugs rescue synaptic plasticity in DYT1 dystonia: Role of M1 muscarinic receptors

Movement disorders, 2014-11, Vol.29 (13), p.1655-1665

2014

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P2.105 The development of positive allosteric modulators of mGluR4 for the treatment of Parkinson's disease

Parkinsonism & related disorders, 2009, Vol.15, p.S117-S117

2009

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Head-to head comparison of mGlu1 and mGlu5 receptor activation in chronic treatment of absence epilepsy in WAG/Rij rats

Neuropharmacology, 2014-10, Vol.85, p.91-103

2014

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N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement

The Journal of pharmacology and experimental therapeutics, 2013-11, Vol.347 (2), p.438-457

2013

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Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M1 PAM

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (6), p.1972-1975

2010

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Potentiation of mGlu5 receptors with the novel enhancer, VU0360172, reduces spontaneous absence seizures in WAG/Rij rats

Neuropharmacology, 2013-03, Vol.66, p.330-338

2013

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Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition

Nature neuroscience, 1998-07, Vol.1 (3), p.185-191

1998

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Chemical lead optimization of a pan G q mAChR M 1, M 3, M 5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M 1 PAM

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (6), p.1972-1975

2010

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Roles of metabotropic glutamate receptors in the hippocampus

Biological psychiatry (1969), 1996-04, Vol.39 (7), p.558-558

Conn, P.J.

1996

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Haloperidol-induced alteration in the physiological actions of group I mGlus in the subthalamic nucleus and the substantia nigra pars reticulata

Neuropharmacology, 2002-08, Vol.43 (2), p.147-159

2002

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Activation of metabotropic glutamate receptor 1 inhibits glutamatergic transmission in the substantia nigra pars reticulata

Neuroscience, 2001-01, Vol.105 (4), p.881-889

2001

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Central serotonin receptors: effector systems, physiological roles and regulation

Psychopharmacologia, 1987, Vol.92 (3), p.267-277

1987

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mGluR5 positive allosteric modulators

Drugs of the Future, 2008-04, Vol.33 (4), p.355

2008

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Selective 5ht-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex

Neuropharmacology, 1984-01, Vol.23 (8), p.993-996

1984

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The antipsychotic potential of muscarinic allosteric modulation

Drug News & Perspectives, 2010-05, Vol.23 (4), p.229-240

2010

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Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus

Brain research, 1987-01, Vol.400 (2), p.396-398

1987

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Glutamate Receptors, Metabotropic

Encyclopedia of Biological Chemistry, 2013, Vol.2, p.395-398

Second Edition, 2013

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Studies in gender

Conn, P.J

1979

Volltextzugriff (PDF)

Acquisition and processing of an intermediate depth walkaway VSP in a UK North Sea Central Graben well

First break, 1995-11, Vol.13 (11), p.435-440

1995

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Metabotropic glutamate receptors: From the workbench to the bedside

Selective potentiation of the metabotropic glutamate receptor subtype 2 blocks phencyclidine-induced hyperlocomotion and brain activation

Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function

Roles of the M4 acetylcholine receptor in the basal ganglia and the treatment of movement disorders

Synthesis and biological characterization of a series of novel diaryl amide M1 antagonists

Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition

Anticholinergic drugs rescue synaptic plasticity in DYT1 dystonia: Role of M1 muscarinic receptors

P2.105 The development of positive allosteric modulators of mGluR4 for the treatment of Parkinson's disease

Head-to head comparison of mGlu1 and mGlu5 receptor activation in chronic treatment of absence epilepsy in WAG/Rij rats

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement

Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M1 PAM

Potentiation of mGlu5 receptors with the novel enhancer, VU0360172, reduces spontaneous absence seizures in WAG/Rij rats

Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition

Chemical lead optimization of a pan G q mAChR M 1, M 3, M 5 positive allosteric modulator (PAM) lead. Part II: Development of a potent and highly selective M 1 PAM

Roles of metabotropic glutamate receptors in the hippocampus

Haloperidol-induced alteration in the physiological actions of group I mGlus in the subthalamic nucleus and the substantia nigra pars reticulata

Activation of metabotropic glutamate receptor 1 inhibits glutamatergic transmission in the substantia nigra pars reticulata

Central serotonin receptors: effector systems, physiological roles and regulation

mGluR5 positive allosteric modulators

Selective 5ht-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex

The antipsychotic potential of muscarinic allosteric modulation

Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus

Glutamate Receptors, Metabotropic

Studies in gender

Acquisition and processing of an intermediate depth walkaway VSP in a UK North Sea Central Graben well

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