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Inhibitors of HIV‑1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir

Journal of medicinal chemistry, 2018-01, Vol.61 (1), p.62-80

2018

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Development of a Practical Synthesis of Functionalized Azaxanthene-Derived Nonsteroidal Glucocorticoid Receptor Modulators

Organic process research & development, 2016-05, Vol.20 (5), p.921-933

2016

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Development of a Practical Synthesis of a Functionalized Pyrrolo[2,1-f][1,2,4]triazine Nucleus

Organic process research & development, 2012-11, Vol.16 (11), p.1846-1853

2012

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Catalytic syn-Selective Direct Aldol Reactions of Benzophenone Glycine Imine with Aromatic, Heteroaromatic and Aliphatic Aldehydes

Advanced synthesis & catalysis, 2015-01, Vol.357 (1), p.28-34

2015

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Considerations for Starting Material Designation for Drug-Linkers in Antibody–Drug Conjugates

Organic process research & development, 2023-07, Vol.27 (7), p.1269-1275

2023

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Development of a Scalable Route to a Dual NK-1/Serotonin Receptor Antagonist

Organic process research & development, 2013-02, Vol.17 (2), p.257-264

2013

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Synthesis of the 6‑Azaindole Containing HIV‑1 Attachment Inhibitor Pro-Drug, BMS-663068

Journal of organic chemistry, 2014-09, Vol.79 (18), p.8757-8767

2014

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Syn-Selective Synthesis of β‑Branched α‑Amino Acids by Alkylation of Glycine-Derived Imines with Secondary Sulfonates

Organic letters, 2015-10, Vol.17 (20), p.5000-5003

2015

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Asymmetric Synthesis of a Potent, Aminopiperidine-Fused Imidazopyridine Dipeptidyl Peptidase IV Inhibitor

Journal of organic chemistry, 2010-03, Vol.75 (5), p.1343-1353

2010

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 7. Development of a Regioselective Ullmann–Goldberg–Buchwald Reaction

Organic process research & development, 2017-08, Vol.21 (8), p.1156-1165

2017

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 5. Selective C‑7 Bromination of the 6‑Azaindole Core

Organic process research & development, 2017-08, Vol.21 (8), p.1137-1144

2017

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 2. Strategic Selections in the Transition from an Enabling Route to a Commercial Synthesis

Organic process research & development, 2017-08, Vol.21 (8), p.1110-1121

2017

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 3. Mechanistic Studies Enable a Scale-Independent Friedel–Crafts Acylation

Organic process research & development, 2017-08, Vol.21 (8), p.1122-1130

2017

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A Partial Classical Resolution/Preparative Chiral Supercritical Fluid Chromatography Method for the Rapid Preparation of the Pivotal Intermediate in the Synthesis of Two Nonsteroidal Glucocorticoid Receptor Modulators

Organic process research & development, 2016-05, Vol.20 (5), p.934-939

2016

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 6. Friedel–Crafts Acylation/Hydrolysis and Amidation

Organic process research & development, 2017-08, Vol.21 (8), p.1145-1155

2017

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 1. Evolution of Enabling Strategies

Organic process research & development, 2017-08, Vol.21 (8), p.1095-1109

2017

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 4. Synthesis of the 6‑Azaindole Core

Organic process research & development, 2017-08, Vol.21 (8), p.1131-1136

2017

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Development of a Process for the Preparation of Chloromethyl Chlorosulfate

Organic process research & development, 2012-11, Vol.16 (11), p.1827-1831

2012

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Translating evidence-based practice: safe and accurate blood pressure measurement in a comprehensive cancer center

Oncology nursing forum, 2010-05, Vol.37 (3), p.264-266

Conlon, David A

2010

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 8. Installation of the Phosphonoxymethyl Prodrug Moiety

Organic process research & development, 2017-08, Vol.21 (8), p.1166-1173

2017

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Preparation of the HIV Attachment Inhibitor BMS-663068. Part 9. Active Pharmaceutical Ingredient Process Development and Powder Properties

Organic process research & development, 2017-08, Vol.21 (8), p.1174-1185

2017

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Development of a New and Practical Route to Chiral 3,4-Disubstituted Cyclopentanones: Asymmetric Alkylation and Intramolecular Cyclopropanation as Key C−C Bond-Forming Steps

Journal of organic chemistry, 2002-08, Vol.67 (16), p.5508-5516

2002

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Suzuki-Miyaura Cross-Coupling With Quasi-Heterogeneous Palladium

Advanced synthesis & catalysis, 2003-08, Vol.345 (8), p.931-935

2003

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Synthetic approaches to a chiral 4-amino-3-hydroxy piperidine with pharmaceutical relevance

Organic & biomolecular chemistry, 2012-07, Vol.10 (27), p.5253-5257

2012

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Discovery of Indazoles as Potent, Orally Active Dual Neurokinin 1 Receptor Antagonists and Serotonin Transporter Inhibitors for the Treatment of Depression

ACS chemical neuroscience, 2016-12, Vol.7 (12), p.1635-1640

2016

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Inhibitors of HIV‑1 Attachment: The Discovery and Development of Temsavir and its Prodrug Fostemsavir

Development of a Practical Synthesis of Functionalized Azaxanthene-Derived Nonsteroidal Glucocorticoid Receptor Modulators

Development of a Practical Synthesis of a Functionalized Pyrrolo[2,1-f][1,2,4]triazine Nucleus

Catalytic syn-Selective Direct Aldol Reactions of Benzophenone Glycine Imine with Aromatic, Heteroaromatic and Aliphatic Aldehydes

Considerations for Starting Material Designation for Drug-Linkers in Antibody–Drug Conjugates

Development of a Scalable Route to a Dual NK-1/Serotonin Receptor Antagonist

Synthesis of the 6‑Azaindole Containing HIV‑1 Attachment Inhibitor Pro-Drug, BMS-663068

Syn-Selective Synthesis of β‑Branched α‑Amino Acids by Alkylation of Glycine-Derived Imines with Secondary Sulfonates

Asymmetric Synthesis of a Potent, Aminopiperidine-Fused Imidazopyridine Dipeptidyl Peptidase IV Inhibitor

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 7. Development of a Regioselective Ullmann–Goldberg–Buchwald Reaction

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 5. Selective C‑7 Bromination of the 6‑Azaindole Core

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 2. Strategic Selections in the Transition from an Enabling Route to a Commercial Synthesis

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 3. Mechanistic Studies Enable a Scale-Independent Friedel–Crafts Acylation

A Partial Classical Resolution/Preparative Chiral Supercritical Fluid Chromatography Method for the Rapid Preparation of the Pivotal Intermediate in the Synthesis of Two Nonsteroidal Glucocorticoid Receptor Modulators

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 6. Friedel–Crafts Acylation/Hydrolysis and Amidation

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 1. Evolution of Enabling Strategies

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 4. Synthesis of the 6‑Azaindole Core

Development of a Process for the Preparation of Chloromethyl Chlorosulfate

Translating evidence-based practice: safe and accurate blood pressure measurement in a comprehensive cancer center

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 8. Installation of the Phosphonoxymethyl Prodrug Moiety

Preparation of the HIV Attachment Inhibitor BMS-663068. Part 9. Active Pharmaceutical Ingredient Process Development and Powder Properties

Development of a New and Practical Route to Chiral 3,4-Disubstituted Cyclopentanones: Asymmetric Alkylation and Intramolecular Cyclopropanation as Key C−C Bond-Forming Steps

Suzuki-Miyaura Cross-Coupling With Quasi-Heterogeneous Palladium

Synthetic approaches to a chiral 4-amino-3-hydroxy piperidine with pharmaceutical relevance

Discovery of Indazoles as Potent, Orally Active Dual Neurokinin 1 Receptor Antagonists and Serotonin Transporter Inhibitors for the Treatment of Depression

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