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Imaging extracellular ATP with a genetically-encoded, ratiometric fluorescent sensor

PloS one, 2017-11, Vol.12 (11), p.e0187481-e0187481

2017

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Detection of Osmotic Shock-Induced Extracellular Nucleotide Release with a Genetically Encoded Fluorescent Sensor of ADP and ATP

Sensors (Basel, Switzerland), 2019-07, Vol.19 (15), p.3253

2019

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Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion

Cell reports (Cambridge), 2022-01, Vol.38 (1), p.110179-110179, Article 110179

2022

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1895-P: Knocking Out Intestinal GPR17 Improves Glucose Homeostasis and Increases Satiety during Fasting-Refeeding Challenge

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles

The Journal of biological chemistry, 2021-07, Vol.297 (1), p.100881-100881, Article 100881

2021

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A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues

The Journal of biological chemistry, 2022-01, Vol.298 (1), p.101431-101431, Article 101431

2022

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Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator in vitro

Islets, 2023-12, Vol.15 (1), p.2267725-2267725

2023

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Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion

Cell reports (Cambridge), 2022-01, Vol.38 (1), p.110179-110179

2022

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Molecular Modeling Evaluation of the Enantiomers of a Novel Adenylyl Cyclase 2 Inhibitor

Journal of chemical information and modeling, 2017-02, Vol.57 (2), p.322-334

2017

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Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

Nutrition & diabetes, 2019-10, Vol.9 (1), p.29-12, Article 29

2019

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Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor

The Journal of pharmacology and experimental therapeutics, 2013-11, Vol.347 (2), p.276-287

2013

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Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti

The Journal of pharmacology and experimental therapeutics, 2015-01, Vol.352 (1), p.53

2015

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Differential Effects of AGS3 Expression on D2L Dopamine Receptor-Mediated Adenylyl Cyclase Signaling

Cellular and molecular neurobiology, 2013-05, Vol.33 (4), p.551-558

2013

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Re-invigorating the insecticide discovery pipeline for vector control: GPCRs as targets for the identification of next gen insecticides

Pesticide biochemistry and physiology, 2013-07, Vol.106 (3), p.141-148

2013

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Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D3 receptor-selective full agonist ligand

Bioorganic & medicinal chemistry, 2012-11, Vol.20 (21), p.6366-6374

2012

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Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications

Journal of visualized experiments, 2014-01 (83), p.e51218-e51218

2014

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Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS

The Journal of biological chemistry, 2008-12, Vol.283 (52), p.36698-36710

2008

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Gαi/o-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later

European journal of pharmacology, 2015-09, Vol.763 (0), p.223-232

2015

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Human GPR17 Nonsynonymous Variants Identified in Individuals with Metabolic Diseases Have Distinct Functional Signaling Profiles

Journal of the Endocrine Society, 2021-05, Vol.5 (Supplement_1), p.A656-A656

2021

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Development and Characterization of a Fluorescent Protein‐Based Biosensor for the Detection of Extracellular ATP

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

Nutrition & diabetes, 2019-12, Vol.9

2019

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Bimolecular Fluorescence Complementation Analysis of G Protein-Coupled Receptor Dimerization in Living Cells

Methods in Enzymology, 2013, Vol.521, p.259-279

2013

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Evaluation of Aa DOP2 Receptor Antagonists Reveals Antidepressants and Antipsychotics as Novel Lead Molecules for Control of the Yellow Fever Mosquito, Aedes aegypti

The Journal of pharmacology and experimental therapeutics, 2015-01, Vol.352 (1), p.53-60

2015

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Identification and characterization of novel small molecule modulators of adenylyl cyclase

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Gα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later

European journal of pharmacology, 2015-09, Vol.763 (Pt B), p.223-232

2015

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Imaging extracellular ATP with a genetically-encoded, ratiometric fluorescent sensor

Detection of Osmotic Shock-Induced Extracellular Nucleotide Release with a Genetically Encoded Fluorescent Sensor of ADP and ATP

Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion

1895-P: Knocking Out Intestinal GPR17 Improves Glucose Homeostasis and Increases Satiety during Fasting-Refeeding Challenge

Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues

Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator in vitro

Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion

Molecular Modeling Evaluation of the Enantiomers of a Novel Adenylyl Cyclase 2 Inhibitor

Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor

Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti

Differential Effects of AGS3 Expression on D2L Dopamine Receptor-Mediated Adenylyl Cyclase Signaling

Re-invigorating the insecticide discovery pipeline for vector control: GPCRs as targets for the identification of next gen insecticides

Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D3 receptor-selective full agonist ligand

Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications

Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS

Gαi/o-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later

Human GPR17 Nonsynonymous Variants Identified in Individuals with Metabolic Diseases Have Distinct Functional Signaling Profiles

Development and Characterization of a Fluorescent Protein‐Based Biosensor for the Detection of Extracellular ATP

Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

Bimolecular Fluorescence Complementation Analysis of G Protein-Coupled Receptor Dimerization in Living Cells

Evaluation of Aa DOP2 Receptor Antagonists Reveals Antidepressants and Antipsychotics as Novel Lead Molecules for Control of the Yellow Fever Mosquito, Aedes aegypti

Identification and characterization of novel small molecule modulators of adenylyl cyclase

Gα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years later

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