UB Paderborn / Katalog / Suche / in CDI

1 – 20 von 20

Sortiert nach

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)

Antimicrobial Agents and Chemotherapy, 2008-12, Vol.52 (12), p.4432-4441

2008

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease

Journal of medicinal chemistry, 2014-03, Vol.57 (5), p.1753-1769

2014

Link zum Volltext

Verfügbarkeit prüfen

Transition States of Epoxidations: Diradical Character, Spiro Geometries, Transition State Flexibility, and the Origins of Stereoselectivity

Journal of the American Chemical Society, 1997-10, Vol.119 (42), p.10147-10152

1997

Link zum Volltext

Verfügbarkeit prüfen

Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activator

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115232-115232, Article 115232

2020

Link zum Volltext

Verfügbarkeit prüfen

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO2 Adduct: Density Functional Theory Transition Structures and Energetics

Journal of the American Chemical Society, 1996-12, Vol.118 (51), p.13002-13006

1996

Link zum Volltext

Verfügbarkeit prüfen

Identification of a New Class of Glucokinase Activators through Structure-Based Design

Journal of medicinal chemistry, 2013-10, Vol.56 (19), p.7669-7678

2013

Link zum Volltext

Verfügbarkeit prüfen

Discovery of 2‑Pyridylureas as Glucokinase Activators

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.8180-8186

2014

Link zum Volltext

Verfügbarkeit prüfen

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394

ACS medicinal chemistry letters, 2016-07, Vol.7 (7), p.714-718

2016

Link zum Volltext

Verfügbarkeit prüfen

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators

ACS medicinal chemistry letters, 2014-12, Vol.5 (12), p.1284-1289

2014

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of (.+-.)-7,8-Epoxy-4-basmen-6-one by a Transannular Cyclization Strategy

Journal of the American Chemical Society, , Vol.117 (11), p.3057-3083

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1709-1718

2004

Link zum Volltext

Verfügbarkeit prüfen

Synthesis of (.+-.)-7,8-epoxy-4-basmen-6-one by a transannular cyclization strategy

Journal of the American Chemical Society, , Vol.115 (17), p.7926-7927

Link zum Volltext

Verfügbarkeit prüfen

Stereoselectivities of Nucleophilic Additions to Cycloheptanones. Experimental and Theoretical Studies and General Purpose Force Field for the Prediction of Nucleophilic Addition Stereoselectivities

Journal of organic chemistry, 1998-05, Vol.63 (10), p.3196-3203

1998

Link zum Volltext

Verfügbarkeit prüfen

Abstract 1464: Pre-clinical characterization of potent and selective next-generation RET inhibitors

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1464-1464

2021

Link zum Volltext

Verfügbarkeit prüfen

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO2 Adduct: Density Functional Theory Transition Structures and Energetics J. Am. Chem. Soc. 1996, 118, 13002

Journal of the American Chemical Society, 1997-03, Vol.119 (12), p.2964-2964

1997

Link zum Volltext

Verfügbarkeit prüfen

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO 2 Adduct: Density Functional Theory Transition Structures and Energetics J. Am. Chem. Soc. 1996 , 118 , 13002

Journal of the American Chemical Society, 1997-03, Vol.119 (12), p.2964-2964

1997

Link zum Volltext

Verfügbarkeit prüfen

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO 2 Adduct: Density Functional Theory Transition Structures and Energetics

Journal of the American Chemical Society, 1996-01, Vol.118 (51), p.13002-13006

1996

Link zum Volltext

Verfügbarkeit prüfen

Stereoselective Synthesis of Polycyclic Ring Systems via the Tandem Diels-Alder Reaction

Journal of organic chemistry, 1994-11, Vol.59 (23), p.6879-6881

1994

Link zum Volltext

Verfügbarkeit prüfen

Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy

Journal of medicinal chemistry, 2019-05, Vol.62 (9), p.4401-4410

2019

Link zum Volltext

Verfügbarkeit prüfen

1 – 20 von 20

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(20)
Mit Volltextzugriff
(20)

Publikationsform

Artikel
(20)

Sprache

Englisch
(20)
Japanisch
(7)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

2 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies

Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease

Transition States of Epoxidations: Diradical Character, Spiro Geometries, Transition State Flexibility, and the Origins of Stereoselectivity

Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activator

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO2 Adduct: Density Functional Theory Transition Structures and Energetics

Identification of a New Class of Glucokinase Activators through Structure-Based Design

Discovery of 2‑Pyridylureas as Glucokinase Activators

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators

Synthesis of (.+-.)-7,8-Epoxy-4-basmen-6-one by a Transannular Cyclization Strategy

Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization

Synthesis of (.+-.)-7,8-epoxy-4-basmen-6-one by a transannular cyclization strategy

Stereoselectivities of Nucleophilic Additions to Cycloheptanones. Experimental and Theoretical Studies and General Purpose Force Field for the Prediction of Nucleophilic Addition Stereoselectivities

Abstract 1464: Pre-clinical characterization of potent and selective next-generation RET inhibitors

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO2 Adduct: Density Functional Theory Transition Structures and Energetics J. Am. Chem. Soc. 1996, 118, 13002

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO 2 Adduct: Density Functional Theory Transition Structures and Energetics J. Am. Chem. Soc. 1996 , 118 , 13002

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO 2 Adduct: Density Functional Theory Transition Structures and Energetics

Stereoselective Synthesis of Polycyclic Ring Systems via the Tandem Diels-Alder Reaction

Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy

Suchergebnisse filtern