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Function and regulation of the Mediator complex

Current opinion in genetics & development, 2011-04, Vol.21 (2), p.225-230

2011

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Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

Cell, 2014-06, Vol.157 (6), p.1430-1444

2014

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The Mediator complex and transcription elongation

Biochimica et biophysica acta, 2013-01, Vol.1829 (1), p.69-75

2013

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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Cell, 2020-03, Vol.180 (6), p.1245-1261.e21

2020

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Multiomic Analysis of the UV-Induced DNA Damage Response

Cell reports (Cambridge), 2016-05, Vol.15 (7), p.1597-1610

2016

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AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Molecular cell, 2010-02, Vol.37 (3), p.429-437

2010

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Mediator structure and rearrangements required for holoenzyme formation

Nature (London), 2017-04, Vol.544 (7649), p.196-201

2017

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Origins and activity of the Mediator complex

Seminars in cell & developmental biology, 2011-09, Vol.22 (7), p.729-734

2011

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Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

Cell, 2011-07, Vol.146 (1), p.92-104

2011

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The INO80 chromatin remodeling complex in transcription, replication and repair

Trends in biochemical sciences (Amsterdam. Regular ed.), 2009-02, Vol.34 (2), p.71-77

2009

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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (33), p.13770-13774

2009

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CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Nature communications, 2018-08, Vol.9 (1), p.3392-13, Article 3392

2018

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Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

The Journal of biological chemistry, 2010-02, Vol.285 (7), p.4268-4272

2010

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Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (51), p.20497-20502

2013

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VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Genes & development, 2004-12, Vol.18 (24), p.3055-3065

2004

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Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (5), p.1454-1459

2008

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The 3' Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies' association with histone locus bodies

Nature communications, 2022-05, Vol.13 (1), p.2905-2905, Article 2905

2022

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NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

Cell reports (Cambridge), 2020-03, Vol.30 (10), p.3478-3491.e6

2020

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A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing

Cell reports (Cambridge), 2019-06, Vol.27 (13), p.3770-3779.e7

2019

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Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1

Nature cell biology, 2006-09, Vol.8 (9), p.994-1002

2006

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Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes

PLoS genetics, 2013-11, Vol.9 (11), p.e1003940-e1003940

2013

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The mammalian Mediator complex and its role in transcriptional regulation

Trends in biochemical sciences (Amsterdam. Regular ed.), 2005-05, Vol.30 (5), p.250-255

2005

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Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate

The Journal of biological chemistry, 2012-12, Vol.287 (52), p.43527-43532

2012

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Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20705-20710

2009

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The role of Mediator and Little Elongation Complex in transcription termination

Nature communications, 2020-02, Vol.11 (1), p.1063-1063, Article 1063

2020

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Function and regulation of the Mediator complex

Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

The Mediator complex and transcription elongation

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Multiomic Analysis of the UV-Induced DNA Damage Response

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Mediator structure and rearrangements required for holoenzyme formation

Origins and activity of the Mediator complex

Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

The INO80 chromatin remodeling complex in transcription, replication and repair

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

The 3' Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies' association with histone locus bodies

NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing

Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1

Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes

The mammalian Mediator complex and its role in transcriptional regulation

Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

The role of Mediator and Little Elongation Complex in transcription termination

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