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Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

Cell, 2014-06, Vol.157 (6), p.1430-1444

2014

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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Cell, 2020-03, Vol.180 (6), p.1245-1261.e21

2020

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Multiomic Analysis of the UV-Induced DNA Damage Response

Cell reports (Cambridge), 2016-05, Vol.15 (7), p.1597-1610

2016

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AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Molecular cell, 2010-02, Vol.37 (3), p.429-437

2010

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Mediator structure and rearrangements required for holoenzyme formation

Nature (London), 2017-04, Vol.544 (7649), p.196-201

2017

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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (33), p.13770-13774

2009

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CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Nature communications, 2018-08, Vol.9 (1), p.3392-13, Article 3392

2018

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Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

The Journal of biological chemistry, 2010-02, Vol.285 (7), p.4268-4272

2010

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Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

Cell, 2011-07, Vol.146 (1), p.92-104

2011

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Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (51), p.20497-20502

2013

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A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing

Cell reports (Cambridge), 2019-06, Vol.27 (13), p.3770-3779.e7

2019

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NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

Cell reports (Cambridge), 2020-03, Vol.30 (10), p.3478-3491.e6

2020

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The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies

Nature communications, 2022-05, Vol.13 (1), p.2905-2905, Article 2905

2022

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Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (5), p.1454-1459

2008

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Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate

The Journal of biological chemistry, 2012-12, Vol.287 (52), p.43527-43532

2012

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The mammalian Mediator complex and its role in transcriptional regulation

Trends in biochemical sciences (Amsterdam. Regular ed.), 2005-05, Vol.30 (5), p.250-255

2005

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Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes

PLoS genetics, 2013-11, Vol.9 (11), p.e1003940-e1003940

2013

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Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20705-20710

2009

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Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1

The EMBO journal, 2008-12, Vol.27 (24), p.3256-3266

2008

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Distinct Modes of Regulation of the Uch37 Deubiquitinating Enzyme in the Proteasome and in the Ino80 Chromatin-Remodeling Complex

Molecular cell, 2008-09, Vol.31 (6), p.909-917

2008

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Biochemical Purification and Pharmacological Inhibition of a Mammalian Prolyl Hydroxylase Acting on Hypoxia-Inducible Factor

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (21), p.13459-13464

2002

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Characterization of Cullin-box Sequences That Direct Recruitment of Cul2-Rbx1 and Cul5-Rbx2 Modules to Elongin BC-based Ubiquitin Ligases

The Journal of biological chemistry, 2008-03, Vol.283 (12), p.8005-8013

2008

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The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME

PloS one, 2012-08, Vol.7 (8), p.e42822-e42822

2012

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MED19 and MED26 Are Synergistic Functional Targets of the RE1 Silencing Transcription Factor in Epigenetic Silencing of Neuronal Gene Expression

The Journal of biological chemistry, 2009-01, Vol.284 (5), p.2648-2656

2009

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Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex

Cell, 2014-07, Vol.158 (2), p.463-463

2014

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Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Multiomic Analysis of the UV-Induced DNA Damage Response

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Mediator structure and rearrangements required for holoenzyme formation

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing

NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate

The mammalian Mediator complex and its role in transcriptional regulation

Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1

Distinct Modes of Regulation of the Uch37 Deubiquitinating Enzyme in the Proteasome and in the Ino80 Chromatin-Remodeling Complex

Biochemical Purification and Pharmacological Inhibition of a Mammalian Prolyl Hydroxylase Acting on Hypoxia-Inducible Factor

Characterization of Cullin-box Sequences That Direct Recruitment of Cul2-Rbx1 and Cul5-Rbx2 Modules to Elongin BC-based Ubiquitin Ligases

The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME

MED19 and MED26 Are Synergistic Functional Targets of the RE1 Silencing Transcription Factor in Epigenetic Silencing of Neuronal Gene Expression

Subunit Architecture and Functional Modular Rearrangements of the Transcriptional Mediator Complex

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