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Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

Cell, 2014-06, Vol.157 (6), p.1430-1444

2014

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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Cell, 2020-03, Vol.180 (6), p.1245-1261.e21

2020

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Multiomic Analysis of the UV-Induced DNA Damage Response

Cell reports (Cambridge), 2016-05, Vol.15 (7), p.1597-1610

2016

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AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Molecular cell, 2010-02, Vol.37 (3), p.429-437

2010

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Mediator structure and rearrangements required for holoenzyme formation

Nature (London), 2017-04, Vol.544 (7649), p.196-201

2017

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The hunt for RNA polymerase II elongation factors: a historical perspective

Nature structural & molecular biology, 2019-09, Vol.26 (9), p.771-776

2019

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Function and regulation of the Mediator complex

Current opinion in genetics & development, 2011-04, Vol.21 (2), p.225-230

2011

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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (33), p.13770-13774

2009

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O-GlcNAc Transferase Catalyzes Site-Specific Proteolysis of HCF-1

Cell, 2011-02, Vol.144 (3), p.376-388

2011

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CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Nature communications, 2018-08, Vol.9 (1), p.3392-13, Article 3392

2018

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A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction

Nature structural & molecular biology, 2013-05, Vol.20 (5), p.611-619

2013

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Quantitative Proteomic Analysis of Distinct Mammalian Mediator Complexes Using Normalized Spectral Abundance Factors

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (50), p.18928-18933

2006

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Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

Cell, 2011-07, Vol.146 (1), p.92-104

2011

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Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

The Journal of biological chemistry, 2010-02, Vol.285 (7), p.4268-4272

2010

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Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes

PLoS genetics, 2013-11, Vol.9 (11), p.e1003940-e1003940

2013

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Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (51), p.20497-20502

2013

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NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

Cell reports (Cambridge), 2020-03, Vol.30 (10), p.3478-3491.e6

2020

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The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies

Nature communications, 2022-05, Vol.13 (1), p.2905-2905, Article 2905

2022

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Elongin functions as a loading factor for Mediator at ATF6α-regulated ER stress response genes

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (39), p.1-10

2021

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Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (5), p.1454-1459

2008

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The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME

PloS one, 2012-08, Vol.7 (8), p.e42822-e42822

2012

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Introduction to Theme "Chromatin, Epigenetics, and Transcription"

Annual review of biochemistry, 2012-01, Vol.81 (1), p.61-64

Conaway, Joan W

2012

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A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing

Cell reports (Cambridge), 2019-06, Vol.27 (13), p.3770-3779.e7

2019

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The Mediator complex and transcription elongation

Biochimica et biophysica acta, 2013-01, Vol.1829 (1), p.69-75

2013

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The mammalian Mediator complex and its role in transcriptional regulation

Trends in biochemical sciences (Amsterdam. Regular ed.), 2005-05, Vol.30 (5), p.250-255

2005

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Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Multiomic Analysis of the UV-Induced DNA Damage Response

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

Mediator structure and rearrangements required for holoenzyme formation

The hunt for RNA polymerase II elongation factors: a historical perspective

Function and regulation of the Mediator complex

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

O-GlcNAc Transferase Catalyzes Site-Specific Proteolysis of HCF-1

CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction

Quantitative Proteomic Analysis of Distinct Mammalian Mediator Complexes Using Normalized Spectral Abundance Factors

Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors

Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex

Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes

Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex

NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation

The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies

Elongin functions as a loading factor for Mediator at ATF6α-regulated ER stress response genes

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME

Introduction to Theme "Chromatin, Epigenetics, and Transcription"

A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing

The Mediator complex and transcription elongation

The mammalian Mediator complex and its role in transcriptional regulation

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