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An mTOR feedback loop mediates the 'flare' ('rebound') response to MET tyrosine kinase inhibition

Scientific reports, 2023-01, Vol.13 (1), p.1378-1378, Article 1378

2023

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Targeting the oncogenic Met receptor by antibodies and gene therapy

Oncogene, 2015-04, Vol.34 (15), p.1883-1889

2015

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Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer

Oncogene, 2013-03, Vol.32 (11), p.1428-1440

2013

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Agonist antibodies activating the Met receptor protect cardiomyoblasts from cobalt chloride-induced apoptosis and autophagy

Cell death & disease, 2014-04, Vol.5 (4), p.e1185-e1185

2014

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Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas

Oncogene, 2000-03, Vol.19 (12), p.1547-1555

2000

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A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth

Oncogene, 2007-02, Vol.26 (7), p.1078-1087

2007

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Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

Nature (London), 1998-01, Vol.391 (6664), p.285-288

1998

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Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth

Oncogene, 2010-09, Vol.29 (38), p.5286-5298

2010

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HGF receptor associates with the anti‐apoptotic protein BAG‐1 and prevents cell death

The EMBO journal, 1996-11, Vol.15 (22), p.6205-6212

1996

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Hepatocyte Growth Factor Is a Potent Angiogenic Factor Which Stimulates Endothelial Cell Motility and Growth

The Journal of cell biology, 1992-11, Vol.119 (3), p.629-641

1992

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Pathway specificity for Met signalling

Nature cell biology, 2001-07, Vol.3 (7), p.E161-E162

Comoglio, Paolo M

2001

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Scatter-factor and semaphorin receptors: cell signalling for invasive growth

Nature reviews. Cancer, 2002-04, Vol.2 (4), p.289-300

2002

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Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

Molecular and Cellular Biology, 1995-02, Vol.15 (2), p.1110-1122

1995

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Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

Cancer cell, 2003-04, Vol.3 (4), p.347-361

2003

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Sustained recruitment of phospholipase C-γ to Gab1 is required for HGF-induced branching tubulogenesis

Oncogene, 2000-03, Vol.19 (12), p.1509-1518

2000

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Plexin signaling hampers integrin‐based adhesion, leading to Rho‐kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility

The FASEB journal, 2004-03, Vol.18 (3), p.592-594

2004

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Cross-talk between the proto-oncogenes Met and Ron

Oncogene, 2000-06, Vol.19 (27), p.3041-3049

2000

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

Cell, 1994-04, Vol.77 (2), p.261-271

1994

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Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas

British journal of cancer, 1996-12, Vol.74 (12), p.1862-1868

1996

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Hepatocyte Growth Factor Is a Regulator of Monocyte-Macrophage Function

The Journal of immunology (1950), 2001-01, Vol.166 (2), p.1241-1247

2001

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Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer

Cancer research (Chicago, Ill.), 1995-03, Vol.55 (5), p.1129-1138

1995

Volltextzugriff (PDF)

Hepatocyte Growth Factor is a Coupling Factor for Osteoclasts and Osteoblasts in vitro

Proceedings of the National Academy of Sciences - PNAS, 1996-07, Vol.93 (15), p.7644-7648

1996

Volltextzugriff (PDF)

Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort

Oncogene, 2017-03, Vol.36 (9), p.1200-1210

2017

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Cancer therapy: can the challenge be MET?

Trends in molecular medicine, 2005-06, Vol.11 (6), p.284-292

2005

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Overexpression of the RON gene in human breast carcinoma

Oncogene, 1998-06, Vol.16 (22), p.2927-2933

1998

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An mTOR feedback loop mediates the 'flare' ('rebound') response to MET tyrosine kinase inhibition

Targeting the oncogenic Met receptor by antibodies and gene therapy

Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer

Agonist antibodies activating the Met receptor protect cardiomyoblasts from cobalt chloride-induced apoptosis and autophagy

Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas

A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth

Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth

HGF receptor associates with the anti‐apoptotic protein BAG‐1 and prevents cell death

Hepatocyte Growth Factor Is a Potent Angiogenic Factor Which Stimulates Endothelial Cell Motility and Growth

Pathway specificity for Met signalling

Scatter-factor and semaphorin receptors: cell signalling for invasive growth

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

Sustained recruitment of phospholipase C-γ to Gab1 is required for HGF-induced branching tubulogenesis

Plexin signaling hampers integrin‐based adhesion, leading to Rho‐kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility

Cross-talk between the proto-oncogenes Met and Ron

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas

Hepatocyte Growth Factor Is a Regulator of Monocyte-Macrophage Function

Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer

Hepatocyte Growth Factor is a Coupling Factor for Osteoclasts and Osteoblasts in vitro

Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort

Cancer therapy: can the challenge be MET?

Overexpression of the RON gene in human breast carcinoma

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