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Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone

Journal of medicinal chemistry, 2011-10, Vol.54 (20), p.7206-7219

2011

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Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors

Clinical cancer research, 2013-06, Vol.19 (11), p.2973-2983

2013

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The search for therapeutic targets in lung cancer: Preclinical and human studies of carcinoembryonic antigen-related cell adhesion molecule 5 expression and its associated molecular landscape

Lung cancer (Amsterdam, Netherlands), 2023-10, Vol.184, p.107356-107356, Article 107356

2023

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An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβ blockade therapy

Acta pharmaceutica Sinica. B, 2022-09, Vol.12 (9), p.3594-3601

2022

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RPR112378 and RPR115781: Two Representatives of a New Family of Microtubule Assembly Inhibitors

Molecular pharmacology, 2000-03, Vol.57 (3), p.553-563

2000

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Abstract CT154: Isatuximab (Isa) plus atezolizumab (Atezo) in patients (pts) with advanced malignancies: Results from a Phase 1/2 open-label multicenter study

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.CT154-CT154

2021

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284 Integrated molecular characterization of primary resistance mechanisms to immune checkpoint blockade in advanced non-small cell lung carcinoma (a-NSCLC)

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A308-A308

2021

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Abstract CT517: Amcenestrant, an oral selective estrogen receptor (ER) degrader (SERD), in ER+/HER2- advanced breast cancer (aBC): combined biomarker analyses from a Phase 1/2 study in postmenopausal women and a Phase 1 study in postmenopausal Japanese women

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.CT517-CT517

2022

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Abstract B145: PK/PD evaluation of an anti-CEACAM5 antibody drug conjugate, in a colon patient-derived-xenografted mice model

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.B145-B145

2015

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Abstract 1688: A novel anti-CEACAM5 maytansinoid-antibody-drug conjugate for the treatment of colorectal, lung and gastric tumors

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1688-1688

2015

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Preclinical Activity of SAR408701: A Novel Anti-CEACAM5-maytansinoid Antibody-drug Conjugate for the Treatment of CEACAM5-positive Epithelial Tumors

Clinical cancer research, 2020-12, Vol.26 (24), p.6589-6599

2020

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Abstract 561: Preclinical efficacy data for the anti-CEACAM5-DM4 ADC SAR408701 supports further development in lung and gastro-intestinal cancers

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.561-561

2020

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Abstract 6182: Artificial intelligence (AI)-powered quantification of glypican-3 (GPC3) expression facilitates patient selection for GPC3-targeted therapy in solid tumors

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.6182-6182

2024

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Abstract 1197: Outstanding preclinical efficacy of a novel maytansinoid-antibody-drug conjugate targeting LAMP1 in patient-derived xenograft solid tumors

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1197-1197

2016

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Predominant Labeling of .beta.- over .alpha.-Tubulin from Porcine Brain by a Photoactivatable Taxoid Derivative

Biochemistry (Easton), 1994-05, Vol.33 (21), p.6676-6683

1994

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Abstract 1198: Characterization of a novel maytansinoid-antibody-drug conjugate targeting LAMP1 expressed at the surface of tumor cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1198-1198

2016

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Interaction between G-actin and myosin subfragment-1 probed by covalent cross-linking

The Journal of biological chemistry, 1992-07, Vol.267 (20), p.14038-14046

1992

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Myosin subfragment-1 interacts with two G-actin molecules in the absence of ATP

The Journal of biological chemistry, 1991-09, Vol.266 (27), p.17872-17879

1991

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Actin polymerization: regulation by divalent metal ion and nucleotide binding, ATP hydrolysis and binding of myosin

Advances in experimental medicine and biology, 1994, Vol.358, p.71

1994

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Covalent modification of G-actin by pyridoxal 5'-phosphate: polymerization properties and interaction with DNase I and myosin subfragment 1

Biochemistry (Easton), 1992-01, Vol.31 (1), p.300-309

1992

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Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells

Genome research, 2016-07, Vol.26 (7), p.908-917

2016

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Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone

SAR156497, an Exquisitely Selective Inhibitor of Aurora Kinases

Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors

The search for therapeutic targets in lung cancer: Preclinical and human studies of carcinoembryonic antigen-related cell adhesion molecule 5 expression and its associated molecular landscape

A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility

Correction to Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-c]pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone

An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβ blockade therapy

RPR112378 and RPR115781: Two Representatives of a New Family of Microtubule Assembly Inhibitors

Abstract CT154: Isatuximab (Isa) plus atezolizumab (Atezo) in patients (pts) with advanced malignancies: Results from a Phase 1/2 open-label multicenter study

284 Integrated molecular characterization of primary resistance mechanisms to immune checkpoint blockade in advanced non-small cell lung carcinoma (a-NSCLC)

Abstract CT517: Amcenestrant, an oral selective estrogen receptor (ER) degrader (SERD), in ER+/HER2- advanced breast cancer (aBC): combined biomarker analyses from a Phase 1/2 study in postmenopausal women and a Phase 1 study in postmenopausal Japanese women

Abstract B145: PK/PD evaluation of an anti-CEACAM5 antibody drug conjugate, in a colon patient-derived-xenografted mice model

Abstract 1688: A novel anti-CEACAM5 maytansinoid-antibody-drug conjugate for the treatment of colorectal, lung and gastric tumors

Preclinical Activity of SAR408701: A Novel Anti-CEACAM5-maytansinoid Antibody-drug Conjugate for the Treatment of CEACAM5-positive Epithelial Tumors

Abstract 561: Preclinical efficacy data for the anti-CEACAM5-DM4 ADC SAR408701 supports further development in lung and gastro-intestinal cancers

Abstract 6182: Artificial intelligence (AI)-powered quantification of glypican-3 (GPC3) expression facilitates patient selection for GPC3-targeted therapy in solid tumors

Abstract 1197: Outstanding preclinical efficacy of a novel maytansinoid-antibody-drug conjugate targeting LAMP1 in patient-derived xenograft solid tumors

Predominant Labeling of .beta.- over .alpha.-Tubulin from Porcine Brain by a Photoactivatable Taxoid Derivative

Abstract 1198: Characterization of a novel maytansinoid-antibody-drug conjugate targeting LAMP1 expressed at the surface of tumor cells

Interaction between G-actin and myosin subfragment-1 probed by covalent cross-linking

Myosin subfragment-1 interacts with two G-actin molecules in the absence of ATP

Actin polymerization: regulation by divalent metal ion and nucleotide binding, ATP hydrolysis and binding of myosin

Covalent modification of G-actin by pyridoxal 5'-phosphate: polymerization properties and interaction with DNase I and myosin subfragment 1

Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells

Le traitement des QPC par les juges de première instance et d’appel dans les ressorts de la Cour administrative d’appel de Bordeaux et des cours d’appel de Bordeaux et d’Agen

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