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A Mechanism for Statin-Induced Susceptibility to Myopathy

JACC. Basic to translational science, 2019-08, Vol.4 (4), p.509-523

2019

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Reversal of Diastereofacial Selectivity in Hydride Reductions of N-tert-Butanesulfinyl Imines

Journal of organic chemistry, 2006-09, Vol.71 (18), p.6859-6862

2006

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Iodide-Catalyzed Reductions: Development of a Synthesis of Phenylacetic Acids

Journal of organic chemistry, 2011-11, Vol.76 (22), p.9519-9524

2011

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Stoichiometric Phosphorylation of Cardiac Ryanodine Receptor on Serine 2809 by Calmodulin-dependent Kinase II and Protein Kinase A

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38593-38600

2003

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Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production

Journal of organic chemistry, 2016-06, Vol.81 (11), p.4736-4743

2016

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Ready display of antigenic peptides in a protein 'mimogen'

Chemical communications (Cambridge, England), 2016-02, Vol.52 (14), p.3014-3017

2016

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DOSCATs: Double standards for protein quantification

Scientific reports, 2017-04, Vol.7 (1), p.45570-45570, Article 45570

2017

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Hydrolysis of Phosphoryl Trichloride (POCl3): Characterization, in Situ Detection, and Safe Quenching of Energetic Metastable Intermediates

Organic process research & development, 2010-11, Vol.14 (6), p.1490-1500

2010

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Ca2+-Dependent Phosphorylation of RyR2 Can Uncouple Channel Gating from Direct Cytosolic Ca2+ Regulation

The Journal of membrane biology, 2011-03, Vol.240 (1), p.21-33

2011

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“Matched/Mismatched” Diastereomeric Dirhodium(II) Carboxamidate Catalyst Pairs. Structure−Selectivity Correlations in Diazo Decomposition and Hetero-Diels−Alder Reactions

Journal of organic chemistry, 2005-06, Vol.70 (13), p.5291-5301

2005

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Development of a Practical Synthesis of a Pyrazolopyridinone-Based p38 MAP Kinase Inhibitor

Organic process research & development, 2011-01, Vol.15 (1), p.31-43

2011

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Myotoxic effects of clenbuterol in the rat heart and soleus muscle

Journal of applied physiology (1985), 2002-11, Vol.93 (5), p.1824-1832

2002

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Chiral Dirhodium(II) Carboxamidate-Catalyzed [2+2]-Cycloaddition of TMS-Ketene and Ethyl Glyoxylate

Advanced synthesis & catalysis, 2005-01, Vol.347 (1), p.87-92

2005

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3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation

Bioorganic & medicinal chemistry letters, 2011-06, Vol.21 (11), p.3384-3389

2011

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Stoichiometric Phosphorylation of Cardiac Ryanodine Receptor on Serine 2809 by Calmodulin-dependent Kinase II and Protein Kinase A

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38593-38600

2003

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Stereoselective Synthesis of Bicyclic Pyrrolidines by a Rhodium-Catalyzed Cascade Process

Angewandte Chemie (International ed.), 2004-12, Vol.43 (48), p.6713-6716

2004

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Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy

ACS nano, 2019-02, Vol.13 (2), p.2143-2157, Article acsnano.8b08742

2019

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Critical Evaluation of Cardiac Ca2+-ATPase Phosphorylation on Serine 38 Using a Phosphorylation Site-specific Antibody

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17111-17119

2004

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Maximum Phosphorylation of the Cardiac Ryanodine Receptor at Serine-2809 by Protein Kinase A Produces Unique Modifications to Channel Gating and Conductance Not Observed at Lower Levels of Phosphorylation

Circulation research, 2006-06, Vol.98 (12), p.1506-1513

2006

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Mechanistic Insights into the Racemization of Fused Cyclopropyl Isoxazolines

Organic letters, 2020-03, Vol.22 (6), p.2113-2117

2020

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Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor

Organic process research & development, 2022-11, Vol.26 (11), p.3115-3125

2022

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Phosphorylation states of phospholamban

Annals of the New York Academy of Sciences, 1998-09, Vol.853 (1), p.79-91

Colyer, J

1998

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Synthesis of dirhodium(II) tetrakis[methyl 1-(3-phenylpropanoyl)-2-oxaimidazolidine-4(S)-carboxylate], Rh2(4S-MPPIM)4

Tetrahedron: asymmetry, 2003-11, Vol.14 (22), p.3601-3604

2003

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Development of a Robust and Highly Selective Ru(II)-Catalyzed Dynamic Kinetic Resolution Used to Manufacture AMG 232

Organic process research & development, 2020-06, Vol.24 (6), p.1164-1174

2020

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Ready display of antigenic peptides in a protein 'mimogen'JC founded and has a financial interest in Badrilla Ltd. JC is an inventor on a patent related to mimogens. MS, JC, BGD developed the concepts. RV, MS, JC, BGD, designed the experimental systems. MS, RV, ZJB performed experiments. Mimogen western analysis was performed at Badrilla and by ZJB. All analysed the results. RV, MS, JC, BGD wrote the manuscript. All read and commented on the manuscript.Electronic supplementary information (ESI)

2016-02

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A Mechanism for Statin-Induced Susceptibility to Myopathy

Reversal of Diastereofacial Selectivity in Hydride Reductions of N-tert-Butanesulfinyl Imines

Iodide-Catalyzed Reductions: Development of a Synthesis of Phenylacetic Acids

Stoichiometric Phosphorylation of Cardiac Ryanodine Receptor on Serine 2809 by Calmodulin-dependent Kinase II and Protein Kinase A

Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production

Ready display of antigenic peptides in a protein 'mimogen'

DOSCATs: Double standards for protein quantification

Hydrolysis of Phosphoryl Trichloride (POCl3): Characterization, in Situ Detection, and Safe Quenching of Energetic Metastable Intermediates

Ca2+-Dependent Phosphorylation of RyR2 Can Uncouple Channel Gating from Direct Cytosolic Ca2+ Regulation

“Matched/Mismatched” Diastereomeric Dirhodium(II) Carboxamidate Catalyst Pairs. Structure−Selectivity Correlations in Diazo Decomposition and Hetero-Diels−Alder Reactions

Development of a Practical Synthesis of a Pyrazolopyridinone-Based p38 MAP Kinase Inhibitor

Myotoxic effects of clenbuterol in the rat heart and soleus muscle

Chiral Dirhodium(II) Carboxamidate-Catalyzed [2+2]-Cycloaddition of TMS-Ketene and Ethyl Glyoxylate

3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation

Stoichiometric Phosphorylation of Cardiac Ryanodine Receptor on Serine 2809 by Calmodulin-dependent Kinase II and Protein Kinase A

Stereoselective Synthesis of Bicyclic Pyrrolidines by a Rhodium-Catalyzed Cascade Process

Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy

Critical Evaluation of Cardiac Ca2+-ATPase Phosphorylation on Serine 38 Using a Phosphorylation Site-specific Antibody

Maximum Phosphorylation of the Cardiac Ryanodine Receptor at Serine-2809 by Protein Kinase A Produces Unique Modifications to Channel Gating and Conductance Not Observed at Lower Levels of Phosphorylation

Mechanistic Insights into the Racemization of Fused Cyclopropyl Isoxazolines

Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor

Phosphorylation states of phospholamban

Synthesis of dirhodium(II) tetrakis[methyl 1-(3-phenylpropanoyl)-2-oxaimidazolidine-4(S)-carboxylate], Rh2(4S-MPPIM)4

Development of a Robust and Highly Selective Ru(II)-Catalyzed Dynamic Kinetic Resolution Used to Manufacture AMG 232

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