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DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies

Molecular oncology, 2022-01, Vol.16 (1), p.11-41

2022

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Low-Dose Hyper-Radiosensitivity: Past, Present, and Future

International journal of radiation oncology, biology, physics, 2008-04, Vol.70 (5), p.1310-1318

2008

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Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia

Molecular cell, 2010-07, Vol.39 (1), p.25-35

2010

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CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability

Molecular cell, 2010-09, Vol.39 (6), p.839-850

2010

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EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7

Journal of cell science, 2020-05, Vol.133 (9)

2020

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RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

Cell, 2008-10, Vol.135 (2), p.261-271

2008

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Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor

PloS one, 2010-06, Vol.5 (6), p.e11208

2010

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FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex

Molecular cell, 2008-11, Vol.32 (3), p.313-324

2008

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The centriolar satellite protein Cep131 is important for genome stability

Journal of cell science, 2012, Vol.125 (Pt 20), p.4770-4779

2012

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MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

Cell reports (Cambridge), 2016-09, Vol.16 (10), p.2565-2575

2016

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Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability

Journal of cell science, 2014-07, Vol.127 (Pt 13), p.2910-2919

2014

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DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair

Molecular and Cellular Biology, 2008-03, Vol.28 (5), p.1470-1479

2008

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Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma

Cancers, 2021-02, Vol.13 (5), p.944

2021

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Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 2; peer review: 2 approved]

F1000 research, 2023, Vol.12, p.954

2023

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Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 1; peer review: 2 approved]

F1000 research, 2023, Vol.12, p.954

2023

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Transition in Survival From Low-Dose Hyper-Radiosensitivity to Increased Radioresistance Is Independent of Activation of ATM SER1981 Activity

International journal of radiation oncology, biology, physics, 2007-11, Vol.69 (4), p.1262-1271

2007

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Evasion of Early Cellular Response Mechanisms following Low Level Radiation-induced DNA Damage

The Journal of biological chemistry, 2004-11, Vol.279 (48), p.49624-49632

2004

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DNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells

British journal of cancer, 2023-11, Vol.129 (11), p.1829-1840

2023

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Emerging links between the biological clock and the DNA damage response

Chromosoma, 2007-08, Vol.116 (4), p.331-339

2007

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Development and Optimisation of Tumour Treating Fields (TTFields) Delivery within 3D Primary Glioma Stem Cell-like Models of Spatial Heterogeneity

Cancers, 2024-02, Vol.16 (5), p.863

2024

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The life and death of DNA-PK

Oncogene, 2005-02, Vol.24 (6), p.949-961

2005

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FANCM-FAAP24 and HCLK2: Roles in ATR signalling and the Fanconi Anemia pathway

Cell cycle (Georgetown, Tex.), 2009-04, Vol.8 (8), p.1133-1137

2009

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Human CDK18 promotes replication stress signaling and genome stability

Nucleic acids research, 2016-10, Vol.44 (18), p.8772-8785

2016

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Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalization via macropinocytosis

Neuro-oncology (Charlottesville, Va.), 2024-04, Vol.26 (4), p.625-639

2024

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Precision oncology using ex vivo technology: a step towards individualised cancer care?

Expert reviews in molecular medicine, 2022-10, Vol.24, p.e39-e39, Article e39

2022

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DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies

Low-Dose Hyper-Radiosensitivity: Past, Present, and Future

Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia

CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability

EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor

FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex

The centriolar satellite protein Cep131 is important for genome stability

MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability

DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair

Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma

Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 2; peer review: 2 approved]

Ex-vivo drug screening of surgically resected glioma stem cells to replace murine avatars and provide personalise cancer therapy for glioblastoma patients [version 1; peer review: 2 approved]

Transition in Survival From Low-Dose Hyper-Radiosensitivity to Increased Radioresistance Is Independent of Activation of ATM SER1981 Activity

Evasion of Early Cellular Response Mechanisms following Low Level Radiation-induced DNA Damage

DNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells

Emerging links between the biological clock and the DNA damage response

Development and Optimisation of Tumour Treating Fields (TTFields) Delivery within 3D Primary Glioma Stem Cell-like Models of Spatial Heterogeneity

The life and death of DNA-PK

FANCM-FAAP24 and HCLK2: Roles in ATR signalling and the Fanconi Anemia pathway

Human CDK18 promotes replication stress signaling and genome stability

Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalization via macropinocytosis

Precision oncology using ex vivo technology: a step towards individualised cancer care?

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