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Anti‐eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis

Allergy (Copenhagen), 2013-03, Vol.68 (3), p.375-385

2013

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Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459

Allergy (Copenhagen), 2014-09, Vol.69 (9), p.1223-1232

2014

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The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial

Allergy (Copenhagen), 2012-12, Vol.67 (12), p.1572-1579

2012

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Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element

Genes and immunity, 2012-09, Vol.13 (6), p.481-488

2012

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Production of Infectious Human Respiratory Syncytial Virus from Cloned cDNA Confirms an Essential Role for the Transcription Elongation Factor from the 5' Proximal Open Reading Frame of the M2 mRNA in Gene Expression and Provides a Capability for Vaccine Development

Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (25), p.11563-11567

1995

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Virus Replication in Engineered Human Cells That Do Not Respond to Interferons

Journal of Virology, 2003-02, Vol.77 (3), p.2174-2181

2003

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Recombinant Respiratory Syncytial Virus That Does Not Express the NS1 or M2-2 Protein Is Highly Attenuated and Immunogenic in Chimpanzees

Journal of Virology, 2000-10, Vol.74 (19), p.9317-9321

2000

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Suppression of the Induction of Alpha, Beta, and Gamma Interferons by the NS1 and NS2 Proteins of Human Respiratory Syncytial Virus in Human Epithelial Cells and Macrophages

Journal of Virology, 2004-04, Vol.78 (8), p.4363-4369

2004

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Recombinant Bovine/Human Parainfluenza Virus Type 3 (B/HPIV3) Expressing the Respiratory Syncytial Virus (RSV) G and F Proteins Can Be Used To Achieve Simultaneous Mucosal Immunization against RSV and HPIV3

Journal of Virology, 2001-05, Vol.75 (10), p.4594-4603

2001

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Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse

Journal of Virology, 1997-12, Vol.71 (12), p.8973-8982

1997

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Severe Acute Respiratory Syndrome Coronavirus Spike Protein Expressed by Attenuated Vaccinia Virus Protectively Immunizes Mice

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (17), p.6641-6646

2004

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Transcription Elongation Factor of Respiratory Syncytial Virus, a Nonsegmented Negative-Strand RNA Virus

Proceedings of the National Academy of Sciences - PNAS, 1996-01, Vol.93 (1), p.81-85

1996

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Contributions of the Structural Proteins of Severe Acute Respiratory Syndrome Coronavirus to Protective Immunity

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (26), p.9804-9809

2004

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Respiratory Syncytial Virus Infection of Human Airway Epithelial Cells Is Polarized, Specific to Ciliated Cells, and without Obvious Cytopathology

Journal of Virology, 2002-06, Vol.76 (11), p.5654-5666

2002

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Granulocyte-Macrophage Colony-Stimulating Factor Expressed by Recombinant Respiratory Syncytial Virus Attenuates Viral Replication and Increases the Level of Pulmonary Antigen-Presenting Cells

Journal of Virology, 2001-12, Vol.75 (24), p.12128-12140

2001

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Identification of a Recombinant Live Attenuated Respiratory Syncytial Virus Vaccine Candidate That Is Highly Attenuated in Infants

The Journal of infectious diseases, 2005-04, Vol.191 (7), p.1093-1104

2005

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Analysis of the gene start and gene end signals of human respiratory syncytial virus: quasi-templated initiation at position 1 of the encoded mRNA

Journal of Virology, 1997-07, Vol.71 (7), p.4944-4953

1997

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A role for immune complexes in enhanced respiratory syncytial virus disease

The Journal of experimental medicine, 2002-09, Vol.196 (6), p.859-865

2002

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Bovine Parainfluenza Virus Type 3 (BPIV3) Fusion and Hemagglutinin-Neuraminidase Glycoproteins Make an Important Contribution to the Restricted Replication of BPIV3 in Primates

Journal of Virology, 2000-10, Vol.74 (19), p.8922-8929

2000

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Genetic diversity between human metapneumovirus subgroups

Virology (New York, N.Y.), 2003-10, Vol.315 (1), p.1-9

2003

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The G Glycoprotein of Human Respiratory Syncytial Viruses of Subgroups A and B: Extensive Sequence Divergence between Antigenically Related Proteins

Proceedings of the National Academy of Sciences - PNAS, 1987-08, Vol.84 (16), p.5625-5629

1987

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The M2-2 Protein of Human Respiratory Syncytial Virus Is a Regulatory Factor Involved in the Balance between RNA Replication and Transcription

Proceedings of the National Academy of Sciences - PNAS, 1999-09, Vol.96 (20), p.11259-11264

1999

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Evaluation of the Replication and Immunogenicity of Recombinant Human Parainfluenza Virus Type 3 Vectors Expressing up to Three Foreign Glycoproteins

Virology (New York, N.Y.), 2002-05, Vol.297 (1), p.136-152

2002

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Role of the M2-1 Transcription Antitermination Protein of Respiratory Syncytial Virus in Sequential Transcription

Journal of Virology, 1999-07, Vol.73 (7), p.5852-5864

1999

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Sendai Virus, a Murine Parainfluenza Virus Type 1, Replicates to a Level Similar to Human PIV1 in the Upper and Lower Respiratory Tract of African Green Monkeys and Chimpanzees

Virology (New York, N.Y.), 2002-05, Vol.297 (1), p.153-160

2002

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Anti‐eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis

Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459

The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial

Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element

Production of Infectious Human Respiratory Syncytial Virus from Cloned cDNA Confirms an Essential Role for the Transcription Elongation Factor from the 5' Proximal Open Reading Frame of the M2 mRNA in Gene Expression and Provides a Capability for Vaccine Development

Virus Replication in Engineered Human Cells That Do Not Respond to Interferons

Recombinant Respiratory Syncytial Virus That Does Not Express the NS1 or M2-2 Protein Is Highly Attenuated and Immunogenic in Chimpanzees

Suppression of the Induction of Alpha, Beta, and Gamma Interferons by the NS1 and NS2 Proteins of Human Respiratory Syncytial Virus in Human Epithelial Cells and Macrophages

Recombinant Bovine/Human Parainfluenza Virus Type 3 (B/HPIV3) Expressing the Respiratory Syncytial Virus (RSV) G and F Proteins Can Be Used To Achieve Simultaneous Mucosal Immunization against RSV and HPIV3

Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse

Severe Acute Respiratory Syndrome Coronavirus Spike Protein Expressed by Attenuated Vaccinia Virus Protectively Immunizes Mice

Transcription Elongation Factor of Respiratory Syncytial Virus, a Nonsegmented Negative-Strand RNA Virus

Contributions of the Structural Proteins of Severe Acute Respiratory Syndrome Coronavirus to Protective Immunity

Respiratory Syncytial Virus Infection of Human Airway Epithelial Cells Is Polarized, Specific to Ciliated Cells, and without Obvious Cytopathology

Granulocyte-Macrophage Colony-Stimulating Factor Expressed by Recombinant Respiratory Syncytial Virus Attenuates Viral Replication and Increases the Level of Pulmonary Antigen-Presenting Cells

Identification of a Recombinant Live Attenuated Respiratory Syncytial Virus Vaccine Candidate That Is Highly Attenuated in Infants

Analysis of the gene start and gene end signals of human respiratory syncytial virus: quasi-templated initiation at position 1 of the encoded mRNA

A role for immune complexes in enhanced respiratory syncytial virus disease

Bovine Parainfluenza Virus Type 3 (BPIV3) Fusion and Hemagglutinin-Neuraminidase Glycoproteins Make an Important Contribution to the Restricted Replication of BPIV3 in Primates

Genetic diversity between human metapneumovirus subgroups

The G Glycoprotein of Human Respiratory Syncytial Viruses of Subgroups A and B: Extensive Sequence Divergence between Antigenically Related Proteins

The M2-2 Protein of Human Respiratory Syncytial Virus Is a Regulatory Factor Involved in the Balance between RNA Replication and Transcription

Evaluation of the Replication and Immunogenicity of Recombinant Human Parainfluenza Virus Type 3 Vectors Expressing up to Three Foreign Glycoproteins

Role of the M2-1 Transcription Antitermination Protein of Respiratory Syncytial Virus in Sequential Transcription

Sendai Virus, a Murine Parainfluenza Virus Type 1, Replicates to a Level Similar to Human PIV1 in the Upper and Lower Respiratory Tract of African Green Monkeys and Chimpanzees

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