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Aging and Parkinson's disease: Different sides of the same coin?

Movement disorders, 2017-07, Vol.32 (7), p.983-990

2017

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Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

Neurobiology of disease, 2015-10, Vol.82, p.185-199

2015

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Genetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia

Movement disorders, 2019-05, Vol.34 (5), p.697-707

2019

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Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

Journal of neuroinflammation, 2018-05, Vol.15 (1), p.129-18, Article 129

2018

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Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils

Neurobiology of disease, 2019-10, Vol.130, p.104525-104525, Article 104525

2019

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Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

Neurobiology of disease, 2023-06, Vol.181, p.106111-106111, Article 106111

2023

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Transfer of host-derived alpha synuclein to grafted dopaminergic neurons in rat

Neurobiology of disease, 2011-09, Vol.43 (3), p.552-557

2011

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Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates

Frontiers in neuroscience, 2016-01, Vol.10, p.12-12

2016

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Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration

The Journal of neuroscience, 2017-07, Vol.37 (28), p.6786-6796

2017

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Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease

The Journal of neuroscience, 2020-04, Vol.40 (18), p.3675-3691

2020

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The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats

Neurobiology of disease, 2021-01, Vol.148, p.105175-105175, Article 105175

2021

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Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease

The Journal of neuroscience, 2015-11, Vol.35 (45), p.14983-14999

2015

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Design and Assembly of CRISPR/Cas9 Lentiviral and rAAV Vectors for Targeted Genome Editing

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1937, p.29

2019

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The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes

PloS one, 2015-05, Vol.10 (5), p.e0127768-e0127768

2015

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Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory

Translational psychiatry, 2022-03, Vol.12 (1), p.93-93, Article 93

2022

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Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson's Disease

Frontiers in neuroscience, 2018-09, Vol.12, p.621

2018

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Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form

Neurobiology of disease, 2017-10, Vol.106, p.191-204

2017

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Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration

PloS one, 2015-09, Vol.10 (9), p.e0137136

2015

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Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats

NPJ Parkinson's Disease, 2024-08, Vol.10 (1), p.163-16

2024

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Interrogating the aged striatum: Robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration

Neurobiology of disease, 2015-05, Vol.77, p.191-203

2015

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Issues in the reporting of epidemiological studies: a survey of recent practice

BMJ (Online), 2004-10, Vol.329 (7471), p.883-887

International edition, 2004

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Tricyclic antidepressant treatment evokes regional changes in neurotrophic factors over time within the intact and degenerating nigrostriatal system

Experimental neurology, 2015-04, Vol.266, p.11-21

2015

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Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

Nature reviews. Neuroscience, 2011-06, Vol.12 (6), p.359-366

2011

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High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine

PloS one, 2015-07, Vol.10 (7), p.e0133957

2015

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Aging and Parkinson's disease: Different sides of the same coin?

Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

Genetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils

Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

Transfer of host-derived alpha synuclein to grafted dopaminergic neurons in rat

Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates

Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration

Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease

The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats

Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease

α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease

Design and Assembly of CRISPR/Cas9 Lentiviral and rAAV Vectors for Targeted Genome Editing

The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes

Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory

Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson's Disease

Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form

Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration

Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats

Interrogating the aged striatum: Robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration

Issues in the reporting of epidemiological studies: a survey of recent practice

Tricyclic antidepressant treatment evokes regional changes in neurotrophic factors over time within the intact and degenerating nigrostriatal system

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine

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