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Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model

The Journal of infectious diseases, 2017-02, Vol.215 (3), p.335-343

2017

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A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Oral Doses of V-7404 in Healthy Adult Volunteers

Antimicrobial agents and chemotherapy, 2021-09, Vol.65 (10)

2021

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An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

Journal of Virology, 2005-10, Vol.79 (20), p.13139-13149

2005

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Clearance of Immunodeficiency-associated Vaccine-derived Poliovirus Infection With Pocapavir

The Pediatric infectious disease journal, 2020-05, Vol.39 (5), p.435

2020

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First use of investigational antiviral drug pocapavir (v-073) for treating neonatal enteroviral sepsis

The Pediatric infectious disease journal, 2015-01, Vol.34 (1), p.52-54

2015

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Progress in the Development of Poliovirus Antiviral Agents and Their Essential Role in Reducing Risks That Threaten Eradication

The Journal of infectious diseases, 2014-11, Vol.210 (suppl 1), p.S447-S453

2014

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Dominant drug targets suppress the emergence of antiviral resistance

eLife, 2014-11, Vol.3

2014

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Enteroviruses in X-Linked Agammaglobulinemia: Update on Epidemiology and Therapy

The journal of allergy and clinical immunology in practice (Cambridge, MA), 2016-11, Vol.4 (6), p.1059-1065

2016

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VP1 Sequencing of All Human Rhinovirus Serotypes: Insights into Genus Phylogeny and Susceptibility to Antiviral Capsid-Binding Compounds

Journal of Virology, 2004-04, Vol.78 (7), p.3663-3674

2004

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Characterization of Poliovirus Variants Selected for Resistance to the Antiviral Compound V-073

Antimicrobial Agents and Chemotherapy, 2012-11, Vol.56 (11), p.5568-5574

2012

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In Vitro Antiviral Activity of V-073 against Polioviruses

Antimicrobial Agents and Chemotherapy, 2009-10, Vol.53 (10), p.4501-4503

2009

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A case for developing antiviral drugs against polio

Antiviral research, 2008-09, Vol.79 (3), p.179-187

2008

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Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses

Antimicrobial Agents and Chemotherapy, 2005-11, Vol.49 (11), p.4492-4499

2005

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Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden

BMJ global health, 2019-08, Vol.4 (4), p.e001613-e001613

2019

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Immunological and pathogenic properties of poliovirus variants selected for resistance to antiviral drug V-073

Antiviral therapy, 2011-10, Vol.16 (7), p.999-1004

2011

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Immunogenicity of Inactivated Polio Vaccine with Concurrent Antiviral V-073 Administration in Mice

Clinical and Vaccine Immunology, 2011-08, Vol.18 (8), p.1387-1390

2011

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N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of Novel Orthopoxvirus Egress Inhibitors

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1442-1444

2007

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Direct random insertion of an influenza virus immunologic determinant into the NS1 glycoprotein of a vaccine flavivirus

Virology (New York, N.Y.), 2010-01, Vol.396 (2), p.329-338

2010

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Insights into the genetic basis for natural phenotypic resistance of human rhinoviruses to pleconaril

Antiviral research, 2005-12, Vol.68 (3), p.135-138

2005

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Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)

Journal of Virology, 2004-09, Vol.78 (18), p.10202-10205

2004

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Infectious bovine viral diarrhea virus (strain NADL) RNA from stable cDNA clones: a cellular insert determines NS3 production and viral cytopathogenicity

Journal of Virology, 1998-06, Vol.72 (6), p.4737-4745

1998

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Mechanism of Action of a Pestivirus Antiviral Compound

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (14), p.7981-7986

2000

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Developing Capsid Inhibitor V-073 for Poliovirus

Antiviral research, 2010-04, Vol.86 (1), p.A53-A53

2010

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HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti‐hepatitis C virus activity In Vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus

Hepatology (Baltimore, Md.), 2009-03, Vol.49 (3), p.745-752

2009

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Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model

A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Oral Doses of V-7404 in Healthy Adult Volunteers

An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

Clearance of Immunodeficiency-associated Vaccine-derived Poliovirus Infection With Pocapavir

First use of investigational antiviral drug pocapavir (v-073) for treating neonatal enteroviral sepsis

Progress in the Development of Poliovirus Antiviral Agents and Their Essential Role in Reducing Risks That Threaten Eradication

Dominant drug targets suppress the emergence of antiviral resistance

Enteroviruses in X-Linked Agammaglobulinemia: Update on Epidemiology and Therapy

VP1 Sequencing of All Human Rhinovirus Serotypes: Insights into Genus Phylogeny and Susceptibility to Antiviral Capsid-Binding Compounds

Characterization of Poliovirus Variants Selected for Resistance to the Antiviral Compound V-073

In Vitro Antiviral Activity of V-073 against Polioviruses

A case for developing antiviral drugs against polio

Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses

Intestinal antibody responses to a live oral poliovirus vaccine challenge among adults previously immunized with inactivated polio vaccine in Sweden

Immunological and pathogenic properties of poliovirus variants selected for resistance to antiviral drug V-073

Immunogenicity of Inactivated Polio Vaccine with Concurrent Antiviral V-073 Administration in Mice

N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of Novel Orthopoxvirus Egress Inhibitors

Direct random insertion of an influenza virus immunologic determinant into the NS1 glycoprotein of a vaccine flavivirus

Insights into the genetic basis for natural phenotypic resistance of human rhinoviruses to pleconaril

The Discovery of Pyrano[3,4-b]indole-Based Allosteric Inhibitors of HCV NS5B Polymerase with In Vivo Activity

Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)

Infectious bovine viral diarrhea virus (strain NADL) RNA from stable cDNA clones: a cellular insert determines NS3 production and viral cytopathogenicity

Mechanism of Action of a Pestivirus Antiviral Compound

Developing Capsid Inhibitor V-073 for Poliovirus

HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti‐hepatitis C virus activity In Vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus

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