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Engineering Closed-Loop, Autoregulatory Gene Circuits for Osteoarthritis Cell-Based Therapies

Current rheumatology reports, 2022-04, Vol.24 (4), p.96-110

Coleman, Rhima M.

2022

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A synthetic, closed‐looped gene circuit for the autonomous regulation of RUNX2 activity during chondrogenesis

The FASEB journal, 2024-02, Vol.38 (4), p.e23484-n/a

2024

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Cartilage thickness mismatches in patellar osteochondral allograft transplants affect local cartilage stresses

Journal of orthopaedic research, 2023-11, Vol.41 (11), p.2372-2383

2023

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Nanowire lasers as intracellular probes

Nanoscale, 2018-01, Vol.10 (20), p.9729-9735

2018

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Photoresponsive Polysaccharide-Based Hydrogels with Tunable Mechanical Properties for Cartilage Tissue Engineering

ACS applied materials & interfaces, 2016-06, Vol.8 (23), p.14423-14429

2016

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Ligand Composition and Coating Density Co-Modulate the Chondrocyte Function on Poly(glycerol-dodecanedioate)

Journal of functional biomaterials, 2023-09, Vol.14 (9), p.468

2023

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The Effect of Articular Cartilage Focal Defect Size and Location in Whole Knee Biomechanics Models

Journal of biomechanical engineering, 2020-02, Vol.142 (2)

2020

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The Influence of Anterior Cruciate Ligament Matrix Mechanical Properties on Simulated Whole-Knee Biomechanics

Journal of biomechanical engineering, 2020-12, Vol.142 (12)

2020

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Bone loss caused by iron overload in a murine model: importance of oxidative stress

Blood, 2010-10, Vol.116 (14), p.2582-2589

2010

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Comparison of bone tissue properties in mouse models with collagenous and non-collagenous genetic mutations using FTIRI

Bone (New York, N.Y.), 2012-11, Vol.51 (5), p.920-928

2012

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Injectable Methacrylated Gelatin Hydrogel for Safe Sodium Hypochlorite Delivery in Endodontics

Gels, 2023-11, Vol.9 (11), p.897

2023

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Hydrogel effects on bone marrow stromal cell response to chondrogenic growth factors

Biomaterials, 2007-04, Vol.28 (12), p.2077-2086

2007

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Characterizing natural hydrogel for reconstruction of three-dimensional lymphoid stromal network to model T-cell interactions

Journal of biomedical materials research. Part A, 2015-08, Vol.103 (8), p.2701-2710

2015

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The Synergistic Effects of Matrix Stiffness and Composition on the Response of Chondroprogenitor Cells in a 3D Precondensation Microenvironment

Advanced healthcare materials, 2016-05, Vol.5 (10), p.1192-1202

2016

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Biomimetic microbeads containing a chondroitin sulfate/chitosan polyelectrolyte complex for cell-based cartilage therapy

Journal of materials chemistry. B, Materials for biology and medicine, 2015-01, Vol.3 (40), p.7920-7929

2015

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Osteoporosis GWAS-implicated DNM3 locus contextually regulates osteoblastic and chondrogenic fate of mesenchymal stem/progenitor cells through oscillating miR-199a-5p levels

JBMR plus, 2024-05, Vol.8 (5), p.ziae051-ziae051

2024

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Phosphate regulates chondrogenesis in a biphasic and maturation-dependent manner

Differentiation (London), 2017-05, Vol.95, p.54-62

2017

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Characterization of a small animal growth plate injury model using microcomputed tomography

Bone (New York, N.Y.), 2010-06, Vol.46 (6), p.1555-1563

2010

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The therapeutic effect of bone marrow-derived stem cell implantation after epiphyseal plate injury is abrogated by chondrogenic predifferentiation

Tissue engineering. Part A, 2013-02, Vol.19 (3-4), p.475-483

2013

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Drug carrier interaction with blood: a critical aspect for high-efficient vascular-targeted drug delivery systems

Therapeutic delivery, 2015-08, Vol.6 (8), p.915-934

2015

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An integrated microwell array platform for cell lasing analysis

Lab on a chip, 2017-08, Vol.17 (16), p.2814-2820

2017

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Formation of Tethers Linking the Epiphysis and Metaphysis Is Regulated by Vitamin D Receptor-Mediated Signaling

Calcified tissue international, 2009-08, Vol.85 (2), p.134-145

2009

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Abstract A40: A novel, biosynthetic 3D hydrogel system for breast cancer mechanobiology studies

Cancer research (Chicago, Ill.), 2017-01, Vol.77 (2_Supplement), p.A40-A40

2017

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Silicon based solvent immersion imprint lithography for rapid polystyrene microfluidic chip prototyping

Sensors and actuators. B, Chemical, 2017-09, Vol.248, p.311-317

2017

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An integrated microwell array platform for cell lasing analysisElectronic supplementary information (ESI) available. See DOI: 10.1039/c7lc00539c

2017-08

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Engineering Closed-Loop, Autoregulatory Gene Circuits for Osteoarthritis Cell-Based Therapies

A synthetic, closed‐looped gene circuit for the autonomous regulation of RUNX2 activity during chondrogenesis

Cartilage thickness mismatches in patellar osteochondral allograft transplants affect local cartilage stresses

Nanowire lasers as intracellular probes

Photoresponsive Polysaccharide-Based Hydrogels with Tunable Mechanical Properties for Cartilage Tissue Engineering

Ligand Composition and Coating Density Co-Modulate the Chondrocyte Function on Poly(glycerol-dodecanedioate)

The Effect of Articular Cartilage Focal Defect Size and Location in Whole Knee Biomechanics Models

The Influence of Anterior Cruciate Ligament Matrix Mechanical Properties on Simulated Whole-Knee Biomechanics

Bone loss caused by iron overload in a murine model: importance of oxidative stress

Comparison of bone tissue properties in mouse models with collagenous and non-collagenous genetic mutations using FTIRI

Injectable Methacrylated Gelatin Hydrogel for Safe Sodium Hypochlorite Delivery in Endodontics

Hydrogel effects on bone marrow stromal cell response to chondrogenic growth factors

Characterizing natural hydrogel for reconstruction of three-dimensional lymphoid stromal network to model T-cell interactions

The Synergistic Effects of Matrix Stiffness and Composition on the Response of Chondroprogenitor Cells in a 3D Precondensation Microenvironment

Biomimetic microbeads containing a chondroitin sulfate/chitosan polyelectrolyte complex for cell-based cartilage therapy

Osteoporosis GWAS-implicated DNM3 locus contextually regulates osteoblastic and chondrogenic fate of mesenchymal stem/progenitor cells through oscillating miR-199a-5p levels

Phosphate regulates chondrogenesis in a biphasic and maturation-dependent manner

Characterization of a small animal growth plate injury model using microcomputed tomography

The therapeutic effect of bone marrow-derived stem cell implantation after epiphyseal plate injury is abrogated by chondrogenic predifferentiation

Drug carrier interaction with blood: a critical aspect for high-efficient vascular-targeted drug delivery systems

An integrated microwell array platform for cell lasing analysis

Formation of Tethers Linking the Epiphysis and Metaphysis Is Regulated by Vitamin D Receptor-Mediated Signaling

Abstract A40: A novel, biosynthetic 3D hydrogel system for breast cancer mechanobiology studies

Silicon based solvent immersion imprint lithography for rapid polystyrene microfluidic chip prototyping

An integrated microwell array platform for cell lasing analysisElectronic supplementary information (ESI) available. See DOI: 10.1039/c7lc00539c

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