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A scalable and operationally simple radical trifluoromethylation

Nature communications, 2015-08, Vol.6 (1), p.7919-7919, Article 7919

2015

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A Visible-Light-Mediated Radical Smiles Rearrangement and its Application to the Synthesis of a Difluoro-Substituted Spirocyclic ORL-1 Antagonist

Angewandte Chemie (International ed.), 2015-12, Vol.54 (49), p.14898-14902

International ed. in English, 2015

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Visible Light Mediated Aryl Migration by Homolytic C−N Cleavage of Aryl Amines

Angewandte Chemie International Edition, 2018-09, Vol.57 (37), p.12167-12170

International ed. in English, 2018

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Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on a Kilogram Scale

Chem, 2016-09, Vol.1 (3), p.456-472

2016

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Small-Volume Continuous Manufacturing of Merestinib. Part 1. Process Development and Demonstration

Organic process research & development, 2019-05, Vol.23 (5), p.858-869

2019

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Total Synthesis of (±)-Phomactin A. Lessons Learned from Respecting a Challenging Structural Topology

Journal of organic chemistry, 2011-09, Vol.76 (17), p.7027-7039

2011

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An Automated Intermittent Flow Approach to Continuous Suzuki Coupling

Organic process research & development, 2016-04, Vol.20 (4), p.820-830

2016

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Directed Ortho Metalation in 2021: A Tribute to Victor Snieckus (August 1, 1937–December 18, 2020)

Organic process research & development, 2021-10, Vol.25 (10), p.2188-2191

2021

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Chemical Synthesis of the GHIJK Ring System and Further Experimental Support for the Originally Assigned Structure of Maitotoxin

Angewandte Chemie (International ed.), 2007-01, Vol.46 (46), p.8875-8879

2007

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Development and a Practical Synthesis of the JAK2 Inhibitor LY2784544

Organic process research & development, 2012-01, Vol.16 (1), p.70-81

2012

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Process Development for a 1H‑Indazole Synthesis Using an Intramolecular Ullmann-Type Reaction

Journal of organic chemistry, 2023-04, Vol.88 (7), p.4209-4223

2023

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Process Development for a 1 H -Indazole Synthesis Using an Intramolecular Ullmann-Type Reaction

Journal of organic chemistry, 2023-04, Vol.88 (7), p.4209-4223

2023

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Kilogram-scale prexasertib monolactate monohydrate synthesis under continuous-flow CGMP conditions

Science (American Association for the Advancement of Science), 2017-06, Vol.356 (6343), p.1144-1150

2017

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Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin

Journal of the American Chemical Society, 2008-06, Vol.130 (23), p.7466-7476

2008

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Total Synthesis and Confirmation of the Revised Structures of Azaspiracid-2 and Azaspiracid-3

Angewandte Chemie (International ed.), 2006-04, Vol.45 (16), p.2609-2615

2006

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Continuous flow technology vs. the batch-by-batch approach to produce pharmaceutical compounds

Expert review of clinical pharmacology, 2018-01, Vol.11 (1), p.5-13

2018

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Intramolecular Formal oxa-[3 + 3] Cycloaddition Approach to the ABD System of Phomactin A

Organic letters, 2003-12, Vol.5 (25), p.4843-4846

2003

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Ligand functionalization as a deactivation pathway in a fac -Ir(ppy) 3 -mediated radical addition

Chemical science (Cambridge), 2015-01, Vol.6 (1), p.537-541

2015

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Sustainability case studies on the use of continuous manufacturing in pharmaceutical production

Current research in green and sustainable chemistry, 2022, Vol.5, p.100279, Article 100279

2022

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Reagent-free continuous thermal tert-butyl ester deprotection

Bioorganic & medicinal chemistry, 2017-12, Vol.25 (23), p.6209-6217

2017

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Small-Volume Continuous Manufacturing of Merestinib. Part 2. Technology Transfer and cGMP Manufacturing

Organic process research & development, 2019-05, Vol.23 (5), p.870-881

2019

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Flow Grignard and Lithiation: Screening Tools and Development of Continuous Processes for a Benzyl Alcohol Starting Material

Organic process research & development, 2016-09, Vol.20 (9), p.1581-1592

2016

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An Alternative Indazole Synthesis for Merestinib

Organic process research & development, 2018-03, Vol.22 (3), p.409-419

2018

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Development of a Scalable Synthesis of Mevidalen (LY3154207), an Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor

Organic process research & development, 2020-11, Vol.24 (11), p.2549-2564

2020

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Preparative Scale Demonstration and Mechanistic Investigation of a Visible Light-Mediated Radical Smiles Rearrangement

Organic process research & development, 2016-07, Vol.20 (7), p.1148-1155

2016

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A scalable and operationally simple radical trifluoromethylation

A Visible-Light-Mediated Radical Smiles Rearrangement and its Application to the Synthesis of a Difluoro-Substituted Spirocyclic ORL-1 Antagonist

Visible Light Mediated Aryl Migration by Homolytic C−N Cleavage of Aryl Amines

Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on a Kilogram Scale

Small-Volume Continuous Manufacturing of Merestinib. Part 1. Process Development and Demonstration

Total Synthesis of (±)-Phomactin A. Lessons Learned from Respecting a Challenging Structural Topology

An Automated Intermittent Flow Approach to Continuous Suzuki Coupling

Directed Ortho Metalation in 2021: A Tribute to Victor Snieckus (August 1, 1937–December 18, 2020)

Chemical Synthesis of the GHIJK Ring System and Further Experimental Support for the Originally Assigned Structure of Maitotoxin

Development and a Practical Synthesis of the JAK2 Inhibitor LY2784544

Process Development for a 1H‑Indazole Synthesis Using an Intramolecular Ullmann-Type Reaction

Process Development for a 1 H -Indazole Synthesis Using an Intramolecular Ullmann-Type Reaction

Kilogram-scale prexasertib monolactate monohydrate synthesis under continuous-flow CGMP conditions

Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin

Total Synthesis and Confirmation of the Revised Structures of Azaspiracid-2 and Azaspiracid-3

Continuous flow technology vs. the batch-by-batch approach to produce pharmaceutical compounds

Intramolecular Formal oxa-[3 + 3] Cycloaddition Approach to the ABD System of Phomactin A

Ligand functionalization as a deactivation pathway in a fac -Ir(ppy) 3 -mediated radical addition

Sustainability case studies on the use of continuous manufacturing in pharmaceutical production

Reagent-free continuous thermal tert-butyl ester deprotection

Small-Volume Continuous Manufacturing of Merestinib. Part 2. Technology Transfer and cGMP Manufacturing

Flow Grignard and Lithiation: Screening Tools and Development of Continuous Processes for a Benzyl Alcohol Starting Material

An Alternative Indazole Synthesis for Merestinib

Development of a Scalable Synthesis of Mevidalen (LY3154207), an Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor

Preparative Scale Demonstration and Mechanistic Investigation of a Visible Light-Mediated Radical Smiles Rearrangement

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