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EADB: an estrogenic activity database for assessing potential endocrine activity

Toxicological sciences, 2013-10, Vol.135 (2), p.277-291

2013

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Inhibition of Cardiac Delayed Rectifier K+ Current by Overexpression of the Long-QT Syndrome HERG G628S Mutation in Transgenic Mice

Circulation research, 1998-09, Vol.83 (6), p.668-678

1998

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Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate : implications for gene-specific therapy

Circulation (New York, N.Y.), 1995-12, Vol.92 (12), p.3381-3386

1995

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Reassessing the validity of surrogate markers of drug efficacy in the treatment of coronary artery disease

Current opinion in investigational drugs (London, England : 2000), 2009-03, Vol.10 (3), p.239

Colatsky, Thomas J

2009

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'Impedance matching' of data sets in biomarker research

Current opinion in investigational drugs (London, England : 2000), 2010-03, Vol.11 (3), p.262

Colatsky, Thomas J

2010

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A return to rational drug discovery: computer-based models of cells, organs and systems in drug target identification

Emerging therapeutic targets, 2000-02, Vol.4 (1), p.39-49

2000

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Comparison of the potassium channel openers, WAY-133537, ZD6169, and celikalim on isolated bladder tissue and In vivo bladder instability in rat

The Journal of pharmacology and experimental therapeutics, 1999-06, Vol.289 (3), p.1410

1999

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What happens when cardiac Na channels lose their function? 1 - Numerical studies of the vulnerable period in tissue expressing mutant channels

Cardiovascular research, 2003, Vol.57 (1), p.82-91

2003

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Emerging Technologies and their Role in Regulatory Review

Drug Discovery Toxicology, 2016, p.1-11

2016

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Metabolic profiling and biomarker discovery

Current opinion in investigational drugs (London, England : 2000), 2003-03, Vol.4 (3), p.262

2003

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Ion Channels: Too Complex for Rational Drug Design?

Neuron, 1996-05, Vol.16 (5), p.913-919

1996

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Antiarrhythmic drug binding sites in cardiac K+ channels

Circulation research, 1996-06, Vol.78 (6), p.1115-1116

Colatsky, T J

1996

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Differential block of cardiac delayed rectifier current by class Ic antiarrhythmic drugs: evidence for open channel block and unblock

Cardiovascular research, 1992-11, Vol.26 (11), p.1121-1130

1992

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Editorial overview. Biomarker-enabled drug discovery: bridging the gap between disease and target knowledge

Current opinion in investigational drugs (London, England : 2000), 2004-03, Vol.5 (3), p.269

2004

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Cellular electrophysiology of WAY-123,398, a new class III antiarrhythmic agent: specificity of IK block and lack of reverse use dependence in cat ventricular myocytes

Cardiovascular research, 1993-09, Vol.27 (9), p.1580-1591

1993

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Effects of WAY-123,398, a New Class III Antiarrhythmic Agent, on Cardiac Refractoriness and Ventricular Fibrillation Threshold in Anesthetized Dogs: A Comparison with UK-68798, E-4031, and dl-Sotalol

Journal of cardiovascular pharmacology, 1992-12, Vol.20 (6), p.913-922

1992

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Commentaries on the Cardiovascular Controversy by W Spinelli and T J Colatsky

Cardiovascular research, 1994-06, Vol.28 (6), p.926-928

1994

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Channel specificity in antiarrhythmic drug action. Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias

Circulation (New York, N.Y.), 1990-12, Vol.82 (6), p.2235-2242

1990

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Block of delayed rectifier potassium current, IK, by flecainide and E-4031 in cat ventricular myocytes

Circulation (New York, N.Y.), 1990-07, Vol.82 (1), p.289-293

1990

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Mechanisms of Action of Lidocaine and Quinidine on Action Potential Duration in Rabbit Cardiac Purkinje Fibers: An Effect on Steady State Sodium Currents?

Circulation research, 1982-01, Vol.50 (1), p.17-27

COLATSKY, THOMAS J

1982

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Potassium channel blockers as antiarrhythmic drugs

Drug development research, 1994-11, Vol.33 (3), p.235-249

1994

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Controlling Cardiac Arrhythmias: New Drugs in Development and Insights From Molecular Biology

Journal of cardiovascular pharmacology and therapeutics, 1998-12, Vol.3 (4), p.337-341

Colatsky, Thomas J.

1998

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The Sicilian Gambit and antiarrhythmic drug development

Cardiovascular research, 1992-06, Vol.26 (6), p.562-565

COLATSKY, T. J

1992

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Antiarrhythmic Drug Binding Sites in Cardiac K sup plus Channels

Circulation research, 1996-06, Vol.78 (6), p.1115-1116

Colatsky, Thomas J

1996

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Tetrodotoxin block of sodium channels in rabbit Purkinje fibers. Interactions between toxin binding and channel gating

The Journal of general physiology, 1981-10, Vol.78 (4), p.383-411

1981

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EADB: an estrogenic activity database for assessing potential endocrine activity

Inhibition of Cardiac Delayed Rectifier K+ Current by Overexpression of the Long-QT Syndrome HERG G628S Mutation in Transgenic Mice

Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate : implications for gene-specific therapy

Reassessing the validity of surrogate markers of drug efficacy in the treatment of coronary artery disease

'Impedance matching' of data sets in biomarker research

A return to rational drug discovery: computer-based models of cells, organs and systems in drug target identification

Comparison of the potassium channel openers, WAY-133537, ZD6169, and celikalim on isolated bladder tissue and In vivo bladder instability in rat

What happens when cardiac Na channels lose their function? 1 - Numerical studies of the vulnerable period in tissue expressing mutant channels

Emerging Technologies and their Role in Regulatory Review

Metabolic profiling and biomarker discovery

Ion Channels: Too Complex for Rational Drug Design?

Antiarrhythmic drug binding sites in cardiac K+ channels

Differential block of cardiac delayed rectifier current by class Ic antiarrhythmic drugs: evidence for open channel block and unblock

Editorial overview. Biomarker-enabled drug discovery: bridging the gap between disease and target knowledge

Cellular electrophysiology of WAY-123,398, a new class III antiarrhythmic agent: specificity of IK block and lack of reverse use dependence in cat ventricular myocytes

Effects of WAY-123,398, a New Class III Antiarrhythmic Agent, on Cardiac Refractoriness and Ventricular Fibrillation Threshold in Anesthetized Dogs: A Comparison with UK-68798, E-4031, and dl-Sotalol

Commentaries on the Cardiovascular Controversy by W Spinelli and T J Colatsky

Channel specificity in antiarrhythmic drug action. Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias

Block of delayed rectifier potassium current, IK, by flecainide and E-4031 in cat ventricular myocytes

Mechanisms of Action of Lidocaine and Quinidine on Action Potential Duration in Rabbit Cardiac Purkinje Fibers: An Effect on Steady State Sodium Currents?

Potassium channel blockers as antiarrhythmic drugs

Controlling Cardiac Arrhythmias: New Drugs in Development and Insights From Molecular Biology

The Sicilian Gambit and antiarrhythmic drug development

Antiarrhythmic Drug Binding Sites in Cardiac K sup plus Channels

Tetrodotoxin block of sodium channels in rabbit Purkinje fibers. Interactions between toxin binding and channel gating

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