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Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation

The Journal of biological chemistry, 2019-03, Vol.294 (10), p.3696-3706

2019

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An acetylation switch controls TDP-43 function and aggregation propensity

Nature communications, 2015-01, Vol.6 (1), p.5845-5845, Article 5845

2015

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Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program

Nature communications, 2017-07, Vol.8 (1), p.82-82, Article 82

2017

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The acetylation of tau inhibits its function and promotes pathological tau aggregation

Nature communications, 2011, Vol.2 (1), p.252-252, Article 252

2011

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TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies

Trends in molecular medicine, 2011-11, Vol.17 (11), p.659-667

2011

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Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

Brain (London, England : 1878), 2012-03, Vol.135 (Pt 3), p.807-818

2012

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An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline

Nature communications, 2020-11, Vol.11 (1), p.5522-18, Article 5522

2020

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A Direct HDAC4-MAP Kinase Crosstalk Activates Muscle Atrophy Program

Molecular cell, 2012-07, Vol.47 (1), p.122-132

2012

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The microtubule-associated tau protein has intrinsic acetyltransferase activity

Nature structural & molecular biology, 2013-06, Vol.20 (6), p.756

2013

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Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation

PloS one, 2016-07, Vol.11 (7), p.e0158470

2016

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A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy

Scientific reports, 2017-03, Vol.7 (1), p.44102-44102, Article 44102

2017

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Clinical Benefits of Remote Versus Transtelephonic Monitoring of Implanted Pacemakers

Journal of the American College of Cardiology, 2009-11, Vol.54 (22), p.2012-2019

2009

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The emerging nontraditional roles for tau in the brain

Cytoskeleton (Hoboken, N.J.), 2024-01, Vol.81 (1), p.89-94

2024

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The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology

Cell reports (Cambridge), 2017-08, Vol.20 (9), p.2169-2183

2017

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Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies

The American journal of pathology, 2013-08, Vol.183 (2), p.344-351

2013

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Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

The EMBO journal, 2012-03, Vol.31 (5), p.1241-1252

2012

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Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase

The Journal of biological chemistry, 2022-06, Vol.298 (6), p.101977-101977, Article 101977

2022

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Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members

PloS one, 2016-12, Vol.11 (12), p.e0168913-e0168913

2016

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Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models

Journal of cell science, 2023-03, Vol.136 (6)

2023

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Tau seeds are subject to aberrant modifications resulting in distinct signatures

Cell reports (Cambridge), 2021-04, Vol.35 (4), p.109037-109037, Article 109037

2021

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Parathyroid Hormone-Related Peptide Represses Chondrocyte Hypertrophy through a Protein Phosphatase 2A/Histone Deacetylase 4/MEF2 Pathway

Molecular and Cellular Biology, 2009-11, Vol.29 (21), p.5751-5762

2009

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Evaluating Fatty Acid Amide Hydrolase as a Suitable Target for Sleep Promotion in a Transgenic TauP301S Mouse Model of Neurodegeneration

Pharmaceuticals (Basel, Switzerland), 2024-02, Vol.17 (3), p.319

2024

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A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation

The Journal of biological chemistry, 2019-11, Vol.294 (45), p.16698-16711

2019

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The Histone Deacetylase HDAC4 Connects Neural Activity to Muscle Transcriptional Reprogramming

The Journal of biological chemistry, 2007-11, Vol.282 (46), p.33752-33759

2007

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Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation

An acetylation switch controls TDP-43 function and aggregation propensity

Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program

Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of more than 3,000 dogs: Determining the optimal age to initiate cancer screening in canine patients

The acetylation of tau inhibits its function and promotes pathological tau aggregation

TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline

A Direct HDAC4-MAP Kinase Crosstalk Activates Muscle Atrophy Program

The microtubule-associated tau protein has intrinsic acetyltransferase activity

Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation

A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy

Clinical Benefits of Remote Versus Transtelephonic Monitoring of Implanted Pacemakers

The emerging nontraditional roles for tau in the brain

The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology

Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies

Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase

Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members

Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models

Tau seeds are subject to aberrant modifications resulting in distinct signatures

Parathyroid Hormone-Related Peptide Represses Chondrocyte Hypertrophy through a Protein Phosphatase 2A/Histone Deacetylase 4/MEF2 Pathway

Evaluating Fatty Acid Amide Hydrolase as a Suitable Target for Sleep Promotion in a Transgenic TauP301S Mouse Model of Neurodegeneration

A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation

The Histone Deacetylase HDAC4 Connects Neural Activity to Muscle Transcriptional Reprogramming

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