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Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: a potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1265

2005

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Androgen Dependent Mammary Gland Virilism in Rats Given the Selective Estrogen Receptor Modulator LY2066948 Hydrochloride

Toxicologic pathology, 2005-10, Vol.33 (6), p.711-719

2005

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Proliferative Lesions of Ovarian Granulosa Cells and Reversible Hormonal Changes Induced in Rats by a Selective Estrogen Receptor Modulator

Toxicologic pathology, 2001-07, Vol.29 (4), p.403-410

2001

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A Selective Estrogen Receptor Modulator Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats

Journal of medicinal chemistry, 2005-11, Vol.48 (22), p.6772-6775

2005

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A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation

Endocrinology (Philadelphia), 2005-10, Vol.146 (10), p.4524-4535

2005

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Androgen dependent mammary gland virilism in rats given the selective estrogen receptor modulator LY2066948 hydrochloride

Toxicologic pathology, 2005-10, Vol.33 (6), p.711-719

2005

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Structure–activity relationships of SERMs optimized for uterine antagonism and ovarian safety

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (13), p.3544-3549

2007

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Proliferative Lesions of Ovarian Granulosa Cells and Reversible Hormonal Changes Induced in Rats by a Selective Estrogen Receptor Modulator

Toxicologic pathology, 2001-11, Vol.29 (6), p.719-726

2001

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The reversible effects of raloxifene on luteinizing hormone levels and ovarian morphology in mice

Reproductive toxicology (Elmsford, N.Y.), 2000, Vol.14 (1), p.37-44

2000

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Hyperprolactinemia alters the frequency and amplitude of pulsatile luteinizing hormone secretion in the ovariectomized rat

Neuroendocrinology, 1986, Vol.42 (4), p.328-333

1986

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Preclinical Pharmacology of FMPD [6-Fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4 H -3-thia-4,9-diaza-benzo[ f ]azulene]: A Potential Novel Antipsychotic with Lower Histamine H 1 Receptor Affinity Than Olanzapine

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1265-1277

2005

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The Selective Estrogen Receptor Modulator, Raloxifene: A Segment II/III Delivery Study in Rats

Reproductive toxicology (Elmsford, N.Y.), 1998-05, Vol.12 (3), p.271-288

1998

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The reversible effects of raloxifene on luteinizing hormone levels and ovarian morphology in mice11A preliminary report of this study was presented at the 54th Annual Meeting of the American Society for Reproductive Medicine, October 3–9, 1998, San Francisco, California

Reproductive toxicology (Elmsford, N.Y.), 2000-01, Vol.14 (1), p.37-44

2000

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Aging Alters the Circadian Rhythm of Glucose Utilization in the Suprachiasmatic Nucleus

Proceedings of the National Academy of Sciences - PNAS, 1988-07, Vol.85 (14), p.5305-5309

1988

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Effects of estradiol on the diurnal rhythm of serotonin activity in microdissected brain areas of ovariectomized rats

Endocrinology (Philadelphia), 1988-06, Vol.122 (6), p.2619-2625

1988

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The Selective Estrogen Receptor Modulator, Raloxifene: A Segment II/III Delivery Study in Rats 11This study (except for immune system assessments) was conducted in accordance with the FDA’s Good Laboratory Practices for Nonclinical Laboratory Studies [1]

Reproductive toxicology (Elmsford, N.Y.), 1998-05, Vol.12 (3), p.271-288

1998

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Steroid treatment fails to induce an afternoon luteinizing hormone or prolactin surge in rats exposed to short-term constant light at the time of ovariectomy

Neuroendocrinology, 1995-09, Vol.62 (3), p.231-237

1995

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Age-related changes in the diurnal rhythm of serotonin turnover in microdissected brain areas of estradiol-treated ovariectomized rats

Endocrinology (Philadelphia), 1988-06, Vol.122 (6), p.2626-2633

1988

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Age-associated alterations in catecholaminergic concentrations, neuronal activity, and α1 receptor densities in female rats

Neurobiology of aging, 1989, Vol.10 (4), p.323-329

1989

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Effects of the serotonin antagonist amesergide on reproduction in female rats

Reproductive toxicology (Elmsford, N.Y.), 1993-11, Vol.7 (6), p.607-612

1993

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Seasonal Changes Associated with Puberty in Female Rats: Effect of Photoperiod and ACTH Administration1

Biology of reproduction, 1979-05, Vol.20 (4), p.757-762

1979

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Lack of effect of hyperprolactinemia on serotonin turnover in ovariectomized and ovariectomized estrogen-treated rats

Brain research, 1989-01, Vol.476 (2), p.400-406

1989

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Seasonal Changes Associated with Puberty in Female Rats: Effect of Photoperiod and ACTH Administration

Biology of reproduction, 1979-05, Vol.20 (4), p.757-762

1979

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Differential suppression of follicle-stimulating hormone and luteinizing hormone secretion in vivo by a gonadotropin-releasing hormone antagonist

Neuroendocrinology, 1985-03, Vol.40 (3), p.246-252

1985

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Inhibitory effects of exogenously induced hyperprolactinemia on the endogenous cyclic release of luteinizing hormone and prolactin in the estrogen-primed ovariectomized rat

Endocrinology (Philadelphia), 1986-10, Vol.119 (4), p.1718-1725

1986

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Preclinical pharmacology of FMPD [6-fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: a potential novel antipsychotic with lower histamine H1 receptor affinity than olanzapine

Androgen Dependent Mammary Gland Virilism in Rats Given the Selective Estrogen Receptor Modulator LY2066948 Hydrochloride

Proliferative Lesions of Ovarian Granulosa Cells and Reversible Hormonal Changes Induced in Rats by a Selective Estrogen Receptor Modulator

A Selective Estrogen Receptor Modulator Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats

A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation

Androgen dependent mammary gland virilism in rats given the selective estrogen receptor modulator LY2066948 hydrochloride

Structure–activity relationships of SERMs optimized for uterine antagonism and ovarian safety

Proliferative Lesions of Ovarian Granulosa Cells and Reversible Hormonal Changes Induced in Rats by a Selective Estrogen Receptor Modulator

The reversible effects of raloxifene on luteinizing hormone levels and ovarian morphology in mice

Hyperprolactinemia alters the frequency and amplitude of pulsatile luteinizing hormone secretion in the ovariectomized rat

Preclinical Pharmacology of FMPD [6-Fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4 H -3-thia-4,9-diaza-benzo[ f ]azulene]: A Potential Novel Antipsychotic with Lower Histamine H 1 Receptor Affinity Than Olanzapine

The Selective Estrogen Receptor Modulator, Raloxifene: A Segment II/III Delivery Study in Rats

The reversible effects of raloxifene on luteinizing hormone levels and ovarian morphology in mice11A preliminary report of this study was presented at the 54th Annual Meeting of the American Society for Reproductive Medicine, October 3–9, 1998, San Francisco, California

Aging Alters the Circadian Rhythm of Glucose Utilization in the Suprachiasmatic Nucleus

Effects of estradiol on the diurnal rhythm of serotonin activity in microdissected brain areas of ovariectomized rats

The Selective Estrogen Receptor Modulator, Raloxifene: A Segment II/III Delivery Study in Rats 11This study (except for immune system assessments) was conducted in accordance with the FDA’s Good Laboratory Practices for Nonclinical Laboratory Studies [1]

Steroid treatment fails to induce an afternoon luteinizing hormone or prolactin surge in rats exposed to short-term constant light at the time of ovariectomy

Age-related changes in the diurnal rhythm of serotonin turnover in microdissected brain areas of estradiol-treated ovariectomized rats

Age-associated alterations in catecholaminergic concentrations, neuronal activity, and α1 receptor densities in female rats

Effects of the serotonin antagonist amesergide on reproduction in female rats

Seasonal Changes Associated with Puberty in Female Rats: Effect of Photoperiod and ACTH Administration1

Lack of effect of hyperprolactinemia on serotonin turnover in ovariectomized and ovariectomized estrogen-treated rats

Seasonal Changes Associated with Puberty in Female Rats: Effect of Photoperiod and ACTH Administration

Differential suppression of follicle-stimulating hormone and luteinizing hormone secretion in vivo by a gonadotropin-releasing hormone antagonist

Inhibitory effects of exogenously induced hyperprolactinemia on the endogenous cyclic release of luteinizing hormone and prolactin in the estrogen-primed ovariectomized rat

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