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Cooperative Lewis acid/N-heterocyclic carbene catalysis

Chemical science (Cambridge), 2012-01, Vol.3 (1), p.53-57

2012

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Mild Palladium-Catalyzed Cyanation of (Hetero)aryl Halides and Triflates in Aqueous Media

Organic letters, 2015-01, Vol.17 (2), p.202-205

2015

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A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

Angewandte Chemie International Edition, 2012-11, Vol.51 (47), p.11686-11698

International ed. in English, 2012

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An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

Angewandte Chemie International Edition, 2012-05, Vol.51 (20), p.4963-4967

International ed. in English, 2012

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Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

Angewandte Chemie (International ed.), 2011-02, Vol.50 (7), p.1678-1682

International ed. in English, 2011

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An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides

Journal of the American Chemical Society, 2015-08, Vol.137 (31), p.9784-9787

2015

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A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products

Angewandte Chemie International Edition, 2017-08, Vol.56 (33), p.9864-9867

International ed. in English, 2017

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Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

Cell reports (Cambridge), 2020-03, Vol.30 (10), p.3229-3239.e6

2020

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NHC-Catalyzed/Titanium(IV)−Mediated Highly Diastereo- and Enantioselective Dimerization of Enals

Organic letters, 2011-03, Vol.13 (5), p.1068-1071

2011

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A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

Nature chemistry, 2019-01, Vol.11 (1), p.78-85

2019

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Enantioselective β‑Protonation by a Cooperative Catalysis Strategy

Journal of the American Chemical Society, 2015-05, Vol.137 (18), p.5891-5894

2015

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Covalent inhibition of pro-apoptotic BAX

Nature chemical biology, 2024-08, Vol.20 (8), p.1022-1032

2024

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Catalytic Dynamic Kinetic Resolutions with N-Heterocyclic Carbenes: Asymmetric Synthesis of Highly Substituted β-Lactones

Angewandte Chemie International Edition, 2012-07, Vol.51 (29), p.7309-7313

2012

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Allosteric inhibition of antiapoptotic MCL-1

Nature structural & molecular biology, 2016-06, Vol.23 (6), p.600-607

2016

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Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization

Molecular cell, 2020-07, Vol.79 (1), p.68-83.e7

2020

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Synthesis, Antimicrobial Evaluation, and Structure–Activity Relationship of α‑Pinene Derivatives

Journal of agricultural and food chemistry, 2014-04, Vol.62 (16), p.3548-3552

2014

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Amide-forming chemical ligation via O-acyl hydroxamic acids

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (15), p.3752-3757

2018

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Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering

Cell chemical biology, 2020-06, Vol.27 (6), p.647-656.e6

2020

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Allosteric sensitization of proapoptotic BAX

Nature chemical biology, 2017-09, Vol.13 (9), p.961-967

2017

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Safety and Efficacy of Transjugular Intrahepatic Portosystemic Shunt Creation for the Treatment of Hepatic Hydrothorax

Journal of vascular and interventional radiology, 2002-04, Vol.13 (4), p.385-390

2002

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Catalytic kinetic resolution of a dynamic racemate: highly stereoselective β-lactone formation by N-heterocyclic carbene catalysis

Chemical science (Cambridge), 2014-05, Vol.5 (5), p.1974-1982

2014

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Catalytic, Enantioselective β‑Protonation through a Cooperative Activation Strategy

Journal of organic chemistry, 2017-05, Vol.82 (9), p.4689-4702

2017

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A neutral pH thermal hydrolysis method for quantification of structured RNAs

RNA (Cambridge), 2014-07, Vol.20 (7), p.1153-1160

2014

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Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application

Chemical communications (Cambridge, England), 2015-02, Vol.51 (13), p.2690-2693

2015

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Abstract 3553: A novel allosteric mechanism for molecular inhibition of anti-apoptotic MCL-1

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3553-3553

2016

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Cooperative Lewis acid/N-heterocyclic carbene catalysis

Mild Palladium-Catalyzed Cyanation of (Hetero)aryl Halides and Triflates in Aqueous Media

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

Lewis Acid Activated Synthesis of Highly Substituted Cyclopentanes by the N-Heterocyclic Carbene Catalyzed Addition of Homoenolate Equivalents to Unsaturated Ketoesters

An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides

A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products

Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

NHC-Catalyzed/Titanium(IV)−Mediated Highly Diastereo- and Enantioselective Dimerization of Enals

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

Enantioselective β‑Protonation by a Cooperative Catalysis Strategy

Covalent inhibition of pro-apoptotic BAX

Catalytic Dynamic Kinetic Resolutions with N-Heterocyclic Carbenes: Asymmetric Synthesis of Highly Substituted β-Lactones

Allosteric inhibition of antiapoptotic MCL-1

Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization

Synthesis, Antimicrobial Evaluation, and Structure–Activity Relationship of α‑Pinene Derivatives

Amide-forming chemical ligation via O-acyl hydroxamic acids

Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering

Allosteric sensitization of proapoptotic BAX

Safety and Efficacy of Transjugular Intrahepatic Portosystemic Shunt Creation for the Treatment of Hepatic Hydrothorax

Catalytic kinetic resolution of a dynamic racemate: highly stereoselective β-lactone formation by N-heterocyclic carbene catalysis

Catalytic, Enantioselective β‑Protonation through a Cooperative Activation Strategy

A neutral pH thermal hydrolysis method for quantification of structured RNAs

Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application

Abstract 3553: A novel allosteric mechanism for molecular inhibition of anti-apoptotic MCL-1

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