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Syntheses of novel high affinity ligands for opioid receptors

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2289-2294

2009

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Syntheses and opioid receptor binding properties of carboxamido-substituted opioids

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.203-208

2009

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Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine

Bioorganic & medicinal chemistry, 2008-05, Vol.16 (10), p.5653-5664

2008

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Synthesis, Binding Affinity, and Functional in Vitro Activity of 3-Benzylaminomorphinan and 3-Benzylaminomorphine Ligands at Opioid Receptors

Journal of medicinal chemistry, 2012-04, Vol.55 (8), p.3878-3890

2012

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8-Carboxamidocyclazocine: a long-acting, novel benzomorphan

The Journal of pharmacology and experimental therapeutics, 2002-07, Vol.302 (1), p.374

2002

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Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 8. High affinity ligands for opioid receptors in the picomolar Ki range: Oxygenated N-(2-[1,1′-biphenyl]-4-ylethyl) analogues of 8-CAC

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7340-7344

2012

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Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.2128-2133

2013

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Redefining the Structure−Activity Relationships of 2,6-Methano-3-benzazocines. 4. Opioid Receptor Binding Properties of 8-[N-(4‘-phenyl)-phenethyl)carboxamido] Analogues of Cyclazocine and Ethylketocycalzocine

Journal of medicinal chemistry, 2006-09, Vol.49 (18), p.5635-5639

2006

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Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4′-phenyl)-phenethyl) analogues of 8-CAC

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6516-6520

2007

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Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 7: Syntheses and opioid receptor properties of cyclic variants of cyclazocine

Bioorganic & medicinal chemistry letters, 2009-01, Vol.19 (2), p.365-368

2009

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Synthesis and Opioid Receptor Affinity of Morphinan and Benzomorphan Derivatives: Mixed κ Agonists and μ Agonists/Antagonists as Potential Pharmacotherapeutics for Cocaine Dependence

Journal of medicinal chemistry, 2000-01, Vol.43 (1), p.114-122

2000

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Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 3: 8-Thiocarboxamido and 8-thioformamido derivatives of cyclazocine

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (10), p.2547-2551

2005

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8-Carboxamidocyclazocine analogues: redefining the structure–activity relationships of 2,6-methano-3-benzazocines

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (5), p.623-626

2001

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3-Carboxamido analogues of morphine and naltrexone: synthesis and opioid receptor binding properties

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (13), p.1717-1721

2001

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Syntheses and Opioid Receptor Binding Affinities of 8-Amino-2,6-methano-3-benzazocines

Journal of medicinal chemistry, 2003-02, Vol.46 (5), p.838-849

2003

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Mixed κ agonists and μ agonists/Antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2735-2740

2001

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8-aminocyclazocine analogues : Synthesis and structure-activity relationships

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (2), p.183-187

2000

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Selective Protection and Functionalization of Morphine: Synthesis and Opioid Receptor Binding Properties of 3-Amino-3-desoxymorphine Derivatives † ,1

Journal of medicinal chemistry, 2000-09, Vol.43 (19), p.3558-3565

2000

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Synthesis and pharmacology of 8-amino-3-[(tetrahydro-2-furanyl)methyl] benzomorphan

Yao hsüeh hsüeh pao, 2003-10, Vol.38 (10), p.748

2003

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Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 6. Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (10), p.5653-5664

2008

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Selective protection and functionalization of morphine: Synthesis and opioid receptor binding properties of 3-amino-3-desoxymorphine derivatives

Journal of medicinal chemistry, 2000-09, Vol.43 (19), p.3558-3565

2000

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3-Carboxamido analogues of morphine and naltrexone

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (13), p.1717-1721

2001

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8-Carboxamidocyclazocine analogues

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (5), p.623-626

2001

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Mixed K agonists and μ agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: Synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (20), p.2735-2740

2001

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ChemInform Abstract: 3-Carboxamido Analogues of Morphine and Naltrexone: Synthesis and Opioid Receptor Binding Properties

ChemInform, 2001-11, Vol.32 (47), p.no-no

2001

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Syntheses of novel high affinity ligands for opioid receptors

Syntheses and opioid receptor binding properties of carboxamido-substituted opioids

Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine

Synthesis, Binding Affinity, and Functional in Vitro Activity of 3-Benzylaminomorphinan and 3-Benzylaminomorphine Ligands at Opioid Receptors

8-Carboxamidocyclazocine: a long-acting, novel benzomorphan

Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 8. High affinity ligands for opioid receptors in the picomolar Ki range: Oxygenated N-(2-[1,1′-biphenyl]-4-ylethyl) analogues of 8-CAC

Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors

Redefining the Structure−Activity Relationships of 2,6-Methano-3-benzazocines. 4. Opioid Receptor Binding Properties of 8-[N-(4‘-phenyl)-phenethyl)carboxamido] Analogues of Cyclazocine and Ethylketocycalzocine

Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4′-phenyl)-phenethyl) analogues of 8-CAC

Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 7: Syntheses and opioid receptor properties of cyclic variants of cyclazocine

Synthesis and Opioid Receptor Affinity of Morphinan and Benzomorphan Derivatives: Mixed κ Agonists and μ Agonists/Antagonists as Potential Pharmacotherapeutics for Cocaine Dependence

Redefining the structure–activity relationships of 2,6-methano-3-benzazocines. Part 3: 8-Thiocarboxamido and 8-thioformamido derivatives of cyclazocine

8-Carboxamidocyclazocine analogues: redefining the structure–activity relationships of 2,6-methano-3-benzazocines

3-Carboxamido analogues of morphine and naltrexone: synthesis and opioid receptor binding properties

Syntheses and Opioid Receptor Binding Affinities of 8-Amino-2,6-methano-3-benzazocines

Mixed κ agonists and μ agonists/Antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan

8-aminocyclazocine analogues : Synthesis and structure-activity relationships

Selective Protection and Functionalization of Morphine: Synthesis and Opioid Receptor Binding Properties of 3-Amino-3-desoxymorphine Derivatives † ,1

Synthesis and pharmacology of 8-amino-3-[(tetrahydro-2-furanyl)methyl] benzomorphan

Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 6. Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine

Selective protection and functionalization of morphine: Synthesis and opioid receptor binding properties of 3-amino-3-desoxymorphine derivatives

3-Carboxamido analogues of morphine and naltrexone

8-Carboxamidocyclazocine analogues

Mixed K agonists and μ agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: Synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan

ChemInform Abstract: 3-Carboxamido Analogues of Morphine and Naltrexone: Synthesis and Opioid Receptor Binding Properties

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