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The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

Nucleic acids research, 2018-01, Vol.46 (2), p.661-676

2018

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GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1

Scientific reports, 2015-12, Vol.5 (1), p.18097-18097, Article 18097

2015

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Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5'-UTR of KRAS oncogene represses translation

Chemical communications (Cambridge, England), 2012-01, Vol.48 (6), p.874-876

2012

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The KRAS Promoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) Polymerase 1 Proteins, Which Recognize a Critical Quadruplex-forming GA-element

The Journal of biological chemistry, 2010-07, Vol.285 (29), p.22003-22016

2010

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G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy

PloS one, 2011-09, Vol.6 (9), p.e24421-e24421

2011

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Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins

Nucleic acids research, 2008-06, Vol.36 (11), p.3765-3780

2008

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Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA

Biochimica et biophysica acta. General subjects, 2017-05, Vol.1861 (5), p.1389-1398

2017

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Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription

Nucleic acids research, 2009-05, Vol.37 (9), p.2841-2853

2009

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Photosensitizers Binding to Nucleic Acids as Anticancer Agents

Future medicinal chemistry, 2016-02, Vol.8 (2), p.179-194

2016

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Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

Nucleic acids research, 2008-06, Vol.36 (10), p.3494-3507

2008

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G-rich Oligonucleotide Inhibits the Binding of a Nuclear Protein to the Ki-ras Promoter and Strongly Reduces Cell Growth in Human Carcinoma Pancreatic Cells

Biochemistry (Easton), 2004-03, Vol.43 (9), p.2512-2523

2004

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G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription

Nucleic acids research, 2006-01, Vol.34 (9), p.2536-2549

2006

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G4 DNA in ras genes and its potential in cancer therapy

Biochimica et biophysica acta, 2016-04, Vol.1859 (4), p.663-674

2016

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HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property

Nucleic acids research, 2014-07, Vol.42 (13), p.8379-8388

2014

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Antisense locked nucleic acids efficiently suppress BCR/ABL and induce cell growth decline and apoptosis in leukemic cells

Molecular cancer therapeutics, 2006-07, Vol.5 (7), p.1683-1692

2006

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Spectroscopic characterization of the oxidation control of the iso-pentaphyrin/pentaphyrin system

Tetrahedron, 2006-08, Vol.62 (34), p.8147-8151

2006

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Synthesis and Biological Evaluation of New Pentaphyrin Macrocycles for Photodynamic Therapy

Journal of medicinal chemistry, 2006-01, Vol.49 (1), p.196-204

2006

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Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRASG-quadruplexes

Chemical communications (Cambridge, England), 2010, Vol.46 (4), p.625-627

2010

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RNA G‑Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9448-9461

2017

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Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

Molecular cancer, 2014-04, Vol.13 (1), p.75-75, Article 75

2014

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MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

Nucleic acids research, 2013-04, Vol.41 (7), p.4049-4064

2013

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Antigene Effect in K562 Cells of a PEG-Conjugated Triplex-Forming Oligonucleotide Targeted to the bcr/abl Oncogene

Biochemistry (Easton), 2002-01, Vol.41 (2), p.502-510

2002

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Anti-gene Effect in Live Cells of AG Motif Triplex-Forming Oligonucleotides Containing an Increasing Number of Phosphorothioate Linkages

Biochemistry (Easton), 2001-02, Vol.40 (5), p.1135-1143

2001

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Photosensitizers binding to nucleic acids as anticancer agents

Future medicinal chemistry, 2016, Vol.8 (2), p.179-194

2016

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Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding

Cancer gene therapy, 2004-07, Vol.11 (7), p.465-476

2004

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The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1

Photoactivated cationic alkyl-substituted porphyrin binding to g4-RNA in the 5'-UTR of KRAS oncogene represses translation

The KRAS Promoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) Polymerase 1 Proteins, Which Recognize a Critical Quadruplex-forming GA-element

G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy

Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins

Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA

Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription

Photosensitizers Binding to Nucleic Acids as Anticancer Agents

Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation

G-rich Oligonucleotide Inhibits the Binding of a Nuclear Protein to the Ki-ras Promoter and Strongly Reduces Cell Growth in Human Carcinoma Pancreatic Cells

G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription

G4 DNA in ras genes and its potential in cancer therapy

HRAS is silenced by two neighboring G-quadruplexes and activated by MAZ, a zinc-finger transcription factor with DNA unfolding property

Antisense locked nucleic acids efficiently suppress BCR/ABL and induce cell growth decline and apoptosis in leukemic cells

Spectroscopic characterization of the oxidation control of the iso-pentaphyrin/pentaphyrin system

Synthesis and Biological Evaluation of New Pentaphyrin Macrocycles for Photodynamic Therapy

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRASG-quadruplexes

RNA G‑Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation

Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

Antigene Effect in K562 Cells of a PEG-Conjugated Triplex-Forming Oligonucleotide Targeted to the bcr/abl Oncogene

Anti-gene Effect in Live Cells of AG Motif Triplex-Forming Oligonucleotides Containing an Increasing Number of Phosphorothioate Linkages

Photosensitizers binding to nucleic acids as anticancer agents

Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding

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