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The influence of the Or and Carotene Hydroxylase genes on carotenoid accumulation in orange carrots [Daucus carota (L.)]

Theoretical and applied genetics, 2021-10, Vol.134 (10), p.3351-3362

2021

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The fragmented mitochondrial ribosomal RNAs of Plasmodium falciparum

PloS one, 2012-06, Vol.7 (6), p.e38320-e38320

2012

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Assessment of covalent binding body burden in Hmrel human hepatocyte co-culture model for metabollically low turnover compounds

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100897, Article 100897

2024

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Marginalized Identity Invocation Online: The Case of President Donald Trump on Twitter

Social media + society, 2020-01, Vol.6 (1), p.205630512091397

2020

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Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs

Chemical research in toxicology, 2024-04, Vol.37 (4), p.540-544

2024

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Carotenoid Presence Is Associated with the Or Gene in Domesticated Carrot

Genetics (Austin), 2018-12, Vol.210 (4), p.1497-1508

2018

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Effects of abiotic stress on physiological plasticity and water use of Setaria viridis (L.)

Plant science (Limerick), 2016-10, Vol.251, p.128-138

2016

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A Dipolar Cycloaddition Reaction To Access 6‑Methyl-4,5,6,7-tetrahydro‑1H‑[1,2,3]triazolo[4,5‑c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate

Journal of medicinal chemistry, 2018-01, Vol.61 (1), p.207-223

2018

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Discovery of a Series of Substituted 1H‑((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.2877-2892

2023

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Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.2877-2892

2023

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Characterization of JNJ-2482272 [4-(4-Methyl-2-(4-(Trifluoromethyl)Phenyl)Thiazole-5-yl) Pyrimidine-2-Amine] As a Strong Aryl Hydrocarbon Receptor Activator in Rat and Human

Drug metabolism and disposition, 2022-08, Vol.50 (8), p.1064-1076

2022

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P150 - Increased identification of low abundant metabolites utilizing automatic background exclusion and specific filtering features of orbitrap ID-X tribrid mass spectrometer

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S68-S68

2020

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4‑Methyl-6,7-dihydro‑4H‑triazolo[4,5‑c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate

Journal of medicinal chemistry, 2017-06, Vol.60 (11), p.4559-4572

2017

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Design, Synthesis, and Preclinical Evaluation of 3‑Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5‑b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9181-9196

2020

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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Journal of medicinal chemistry, 2022-11, Vol.65 (21), p.14326-14336

2022

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Identification of (R)‑(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro‑1H‑imidazo[4,5‑c]pyridin-5(4H)‑yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8535-8548

2016

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A Facile chemical derivatization method to discern the identity of glucronide conjugates of carboxylic acid drugs under mild conditions

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S62-S62

2019

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Education Coverage in Television News: A Typology and Analysis of 35 Years of Topics

AERA open, 2018-01, Vol.4 (1), p.233285841775169

2018

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Hostile News: Partisan Use and Perceptions of Cable News Programming

Journal of communication, 2008-06, Vol.58 (2), p.201-219

2008

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Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity

ACS medicinal chemistry letters, 2021-05, Vol.12 (5), p.782-790

2021

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A Phase 1 First‐in‐Human Pharmacokinetic and Pharmacodynamic Study of JNJ‐64264681, a Covalent Inhibitor of Bruton's Tyrosine Kinase

Clinical pharmacology in drug development, 2023-06, Vol.12 (6), p.611-624

2023

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Online and Uncivil? Patterns and Determinants of Incivility in Newspaper Website Comments

Journal of communication, 2014-08, Vol.64 (4), p.658-679

2014

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Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin‑1 Antagonists: Discovery of JNJ-54717793

ACS medicinal chemistry letters, 2020-10, Vol.11 (10), p.2002-2009

2020

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Perceptions of Uncivil Discourse Online: An Examination of Types and Predictors

Communication research, 2020-08, Vol.47 (6), p.795-814

2020

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1 H -Pyrrolo[3,2- b ]pyridine GluN2B-Selective Negative Allosteric Modulators

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.261-266

2019

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The influence of the Or and Carotene Hydroxylase genes on carotenoid accumulation in orange carrots [Daucus carota (L.)]

The fragmented mitochondrial ribosomal RNAs of Plasmodium falciparum

Assessment of covalent binding body burden in Hmrel human hepatocyte co-culture model for metabollically low turnover compounds

Marginalized Identity Invocation Online: The Case of President Donald Trump on Twitter

Application of Covalent Binding Body Burden in the HμREL Human Hepatocyte Coculture Model for Reactivity Risk Assessment of Metabolically Low Turnover Drugs

Carotenoid Presence Is Associated with the Or Gene in Domesticated Carrot

Effects of abiotic stress on physiological plasticity and water use of Setaria viridis (L.)

A Dipolar Cycloaddition Reaction To Access 6‑Methyl-4,5,6,7-tetrahydro‑1H‑[1,2,3]triazolo[4,5‑c]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate

Discovery of a Series of Substituted 1H‑((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators

Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators

Characterization of JNJ-2482272 [4-(4-Methyl-2-(4-(Trifluoromethyl)Phenyl)Thiazole-5-yl) Pyrimidine-2-Amine] As a Strong Aryl Hydrocarbon Receptor Activator in Rat and Human

P150 - Increased identification of low abundant metabolites utilizing automatic background exclusion and specific filtering features of orbitrap ID-X tribrid mass spectrometer

4‑Methyl-6,7-dihydro‑4H‑triazolo[4,5‑c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate

Design, Synthesis, and Preclinical Evaluation of 3‑Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5‑b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders

Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Identification of (R)‑(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro‑1H‑imidazo[4,5‑c]pyridin-5(4H)‑yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor

A Facile chemical derivatization method to discern the identity of glucronide conjugates of carboxylic acid drugs under mild conditions

Education Coverage in Television News: A Typology and Analysis of 35 Years of Topics

Hostile News: Partisan Use and Perceptions of Cable News Programming

Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity

A Phase 1 First‐in‐Human Pharmacokinetic and Pharmacodynamic Study of JNJ‐64264681, a Covalent Inhibitor of Bruton's Tyrosine Kinase

Online and Uncivil? Patterns and Determinants of Incivility in Newspaper Website Comments

Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin‑1 Antagonists: Discovery of JNJ-54717793

Perceptions of Uncivil Discourse Online: An Examination of Types and Predictors

1 H -Pyrrolo[3,2- b ]pyridine GluN2B-Selective Negative Allosteric Modulators

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