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Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

Nature communications, 2014-10, Vol.5 (1), p.5056, Article 5056

2014

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A human receptor occupancy assay to measure anti‐PD‐1 binding in patients with prior anti‐PD‐1

Cytometry. Part A, 2021-08, Vol.99 (8), p.832-843

2021

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Beyond checkpoint inhibition: PD-1 cis-targeting of an IL-2Rβγ-biased interleukin-2 variant as a novel approach to build on checkpoint inhibition

Oncoimmunology, 2023, Vol.12 (1), p.2197360-2197360

2023

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Cytokine Complex―expanded Natural Killer Cells Improve Allogeneic Lung Transplant Function via Depletion of Donor Dendritic Cells

American journal of respiratory and critical care medicine, 2013-06, Vol.187 (12), p.1349-1359

2013

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Mast cell-derived mediators promote murine neutrophil effector functions

International immunology, 2013-10, Vol.25 (10), p.553-561

2013

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Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (41), p.16233-16238

2007

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863 Novel radioimmunotherapy for lung cancer: a tumor targeting approach

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A963-A963

2023

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Abstract 2270: RG7769 (PD1-TIM3), a novel heterodimeric avidity-driven T cell specific PD-1/TIM-3 bispecific antibody lacking Fc-mediated effector functions for dual checkpoint inhibition to reactivate dysfunctional T cells

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2270-2270

2020

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RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

Nature immunology, 2011-06, Vol.12 (6), p.560-567

2011

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Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors

Journal for immunotherapy of cancer, 2022-11, Vol.10 (11), p.e005548

2022

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Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease

Trends in immunology, 2013-03, Vol.34 (3), p.114-119

2013

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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

Immunity (Cambridge, Mass.), 2023-01, Vol.56 (1), p.162-179.e6

2023

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Cytokine networks in multiple sclerosis: lost in translation

Current opinion in neurology, 2010-06, Vol.23 (3), p.205-211

2010

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Monitoring of CD4+CD25highIL-7Rαhigh activated T Cells in Kidney Transplant Recipients

Clinical journal of the American Society of Nephrology, 2011-08, Vol.6 (8), p.2025-2033

2011

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Abstract B004: Identifying response factors to PD1-IL2v therapy

Cancer immunology research, 2024-10, Vol.12 (10_Supplement), p.B004-B004

2024

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Abstract 2070: Differentiating PD-1+TCF-1+ stem-like resource CD8 T cells towards a distinct effector Tcell population with enhanced anti-tumor potential by delivering an engineered IL-2 variant to PD-1 via cis -targeting

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2070-2070

2022

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Pharmacologic Inhibitors of STAT3 or BCL6 Transcriptional Function Sensitize Lymphoma Cells to the Novel PD-1 Cis-Targeted PD1-IL2v Immunocytokine in a Murine Model

Blood, 2022-11, Vol.140 (Supplement 1), p.8835-8836

2022

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Abstract 5747: A novel combination therapy of arenavirus vectors and PD1-IL2v strongly potentiates tumor specific T cell responses resulting in synergistic anti-tumor efficacy

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5747-5747

2023

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Abstract 71: The immunocytokine PD1-IL2v overcomes immune checkpoint resistance, and combination with an anti-PD-L1 antibody further enhances its anti-tumor activity

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.71-71

2021

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Abstract 4158: Selective targeting of CD122 combined with radiotherapy triggers CD8 and NK mediated immunity, abrogating metastasis in head and neck squamous cell carcinoma

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.4158-4158

2023

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Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC

Cell reports. Medicine, 2023-08, Vol.4 (8), p.101150-101150, Article 101150

2023

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Mast cell-derived mediators promote murine neutrophil effector functions

International immunology, 2013-10, Vol.25 (10), p.553-561

2013

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Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis

Cancer cell, 2023-05, Vol.41 (5), p.950-969.e6

2023

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Lifelong dynamics of human CD4 +CD25 + regulatory T cells: Insights from in vivo data and mathematical modeling

Journal of theoretical biology, 2010-09, Vol.266 (2), p.307-322

2010

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Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

A human receptor occupancy assay to measure anti‐PD‐1 binding in patients with prior anti‐PD‐1

PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells

Beyond checkpoint inhibition: PD-1 cis-targeting of an IL-2Rβγ-biased interleukin-2 variant as a novel approach to build on checkpoint inhibition

Cytokine Complex―expanded Natural Killer Cells Improve Allogeneic Lung Transplant Function via Depletion of Donor Dendritic Cells

Mast cell-derived mediators promote murine neutrophil effector functions

Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype

863 Novel radioimmunotherapy for lung cancer: a tumor targeting approach

Abstract 2270: RG7769 (PD1-TIM3), a novel heterodimeric avidity-driven T cell specific PD-1/TIM-3 bispecific antibody lacking Fc-mediated effector functions for dual checkpoint inhibition to reactivate dysfunctional T cells

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors

Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease

Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages

Cytokine networks in multiple sclerosis: lost in translation

Monitoring of CD4+CD25highIL-7Rαhigh activated T Cells in Kidney Transplant Recipients

Abstract B004: Identifying response factors to PD1-IL2v therapy

Abstract 2070: Differentiating PD-1+TCF-1+ stem-like resource CD8 T cells towards a distinct effector Tcell population with enhanced anti-tumor potential by delivering an engineered IL-2 variant to PD-1 via cis -targeting

Pharmacologic Inhibitors of STAT3 or BCL6 Transcriptional Function Sensitize Lymphoma Cells to the Novel PD-1 Cis-Targeted PD1-IL2v Immunocytokine in a Murine Model

Abstract 5747: A novel combination therapy of arenavirus vectors and PD1-IL2v strongly potentiates tumor specific T cell responses resulting in synergistic anti-tumor efficacy

Abstract 71: The immunocytokine PD1-IL2v overcomes immune checkpoint resistance, and combination with an anti-PD-L1 antibody further enhances its anti-tumor activity

Abstract 4158: Selective targeting of CD122 combined with radiotherapy triggers CD8 and NK mediated immunity, abrogating metastasis in head and neck squamous cell carcinoma

Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC

Mast cell-derived mediators promote murine neutrophil effector functions

Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis

Lifelong dynamics of human CD4 +CD25 + regulatory T cells: Insights from in vivo data and mathematical modeling

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