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Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

Aging (Albany, NY.), 2016-04, Vol.8 (4), p.796-809

2016

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Humanin: a novel central regulator of peripheral insulin action

PloS one, 2009-07, Vol.4 (7), p.e6334

2009

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Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice

Atherosclerosis, 2011-11, Vol.219 (1), p.65-73

2011

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IGFBP-3 Is a Metastasis Suppression Gene in Prostate Cancer

Cancer research (Chicago, Ill.), 2011-08, Vol.71 (15), p.5154-5163

2011

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Opposing Roles of Insulin-Like Growth Factor Binding Protein 3 and Humanin in the Regulation of Testicular Germ Cell Apoptosis

Endocrinology (Philadelphia), 2010-01, Vol.151 (1), p.350-357

2010

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Insulin-Like Growth Factor-Binding Protein 5 (Igfbp5) Compromises Survival, Growth, Muscle Development, and Fertility in Mice

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (12), p.4314-4319

2004

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Interaction of Insulin-like Growth Factor-binding Protein-3 and BAX in Mitochondria Promotes Male Germ Cell Apoptosis

The Journal of biological chemistry, 2010-01, Vol.285 (3), p.1726-1732

2010

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PAPA-1 Is a Nuclear Binding Partner of IGFBP-2 and Modulates Its Growth-Promoting Actions

Molecular endocrinology (Baltimore, Md.), 2009-02, Vol.23 (2), p.169-175

2009

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Akt2, a Novel Functional Link between p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways in Myogenesis

Molecular and Cellular Biology, 2004-05, Vol.24 (9), p.3607-3622

2004

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The neurosurvival factor Humanin inhibits β -cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice

Metabolism, clinical and experimental, 2010-03, Vol.59 (3), p.343-349

2010

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Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress

Cardiovascular research, 2010-11, Vol.88 (2), p.360-366

2010

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Partitioning of IGFBP-5 actions in myogenesis: IGF-independent anti-apoptotic function

Journal of cell science, 2004-04, Vol.117 (Pt 9), p.1737-1746

2004

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Pharmacokinetics and Tissue Distribution of Humanin and Its Analogues in Male Rodents

Endocrinology (Philadelphia), 2013-10, Vol.154 (10), p.3739-3744

2013

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Enhancing the Apoptotic Potential of Insulin-Like Growth Factor-Binding Protein-3 in Prostate Cancer by Modulation of CK2 Phosphorylation

Molecular endocrinology (Baltimore, Md.), 2009-10, Vol.23 (10), p.1624-1633

2009

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Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF–IGFBP axis

Growth hormone & IGF research, 2010-02, Vol.20 (1), p.55-62

2010

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Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression

Cancer research (Chicago, Ill.), 2008-05, Vol.68 (9), p.3342-3349

2008

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IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo

The FASEB journal, 2009-08, Vol.23 (8), p.2616-2626

2009

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Phosphorylation by DNA-dependent protein kinase is critical for apoptosis induction by insulin-like growth factor binding protein-3

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (22), p.10878-10884

2006

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MEK5 and ERK5 are mediators of the pro-myogenic actions of IGF-2

Journal of cell science, 2009-09, Vol.122 (17), p.3104-3112

2009

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Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3

Carcinogenesis (New York), 2007-08, Vol.28 (8), p.1653-1658

2007

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Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation

Journal of cell science, 2006-12, Vol.119 (23), p.4828-4840

2006

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Abstract 2848: SHLP6: A naturally occurring mitochondrial-derived peptide has therapeutic potential in prostate cancer

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.2848-2848

2011

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The cytoprotective peptide humanin is induced and neutralizes Bax after pro‐apoptotic stress in the rat testis

Andrology (Oxford), 2013-07, Vol.1 (4), p.651-659

2013

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The neurosurvival factor Humanin inhibits b-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice

Metabolism, clinical and experimental, 2010-03, Vol.59 (3), p.343-349

2010

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O2-1 HNGF6A, a novel, non-IGFBP-3 binding, humanin analog, with enhanced biological activity, superior pharmacokinetic profile, and no perturbation of the IGF system

ENDOCRINE JOURNAL, 2010, Vol.57 (suppl.2-1), p.S334-S334

2010

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Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

Humanin: a novel central regulator of peripheral insulin action

Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice

IGFBP-3 Is a Metastasis Suppression Gene in Prostate Cancer

Opposing Roles of Insulin-Like Growth Factor Binding Protein 3 and Humanin in the Regulation of Testicular Germ Cell Apoptosis

Insulin-Like Growth Factor-Binding Protein 5 (Igfbp5) Compromises Survival, Growth, Muscle Development, and Fertility in Mice

Interaction of Insulin-like Growth Factor-binding Protein-3 and BAX in Mitochondria Promotes Male Germ Cell Apoptosis

PAPA-1 Is a Nuclear Binding Partner of IGFBP-2 and Modulates Its Growth-Promoting Actions

Akt2, a Novel Functional Link between p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways in Myogenesis

The neurosurvival factor Humanin inhibits β -cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice

Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress

Partitioning of IGFBP-5 actions in myogenesis: IGF-independent anti-apoptotic function

Pharmacokinetics and Tissue Distribution of Humanin and Its Analogues in Male Rodents

Enhancing the Apoptotic Potential of Insulin-Like Growth Factor-Binding Protein-3 in Prostate Cancer by Modulation of CK2 Phosphorylation

Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF–IGFBP axis

Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression

IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo

Phosphorylation by DNA-dependent protein kinase is critical for apoptosis induction by insulin-like growth factor binding protein-3

MEK5 and ERK5 are mediators of the pro-myogenic actions of IGF-2

Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3

Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation

Abstract 2848: SHLP6: A naturally occurring mitochondrial-derived peptide has therapeutic potential in prostate cancer

The cytoprotective peptide humanin is induced and neutralizes Bax after pro‐apoptotic stress in the rat testis

The neurosurvival factor Humanin inhibits b-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice

O2-1 HNGF6A, a novel, non-IGFBP-3 binding, humanin analog, with enhanced biological activity, superior pharmacokinetic profile, and no perturbation of the IGF system

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