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AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud

PloS one, 2012-08, Vol.7 (8), p.e43279-e43279

2012

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Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts

Beilstein journal of organic chemistry, 2016-03, Vol.12 (1), p.429-443

2016

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Targeted Activation of Toll-Like Receptors: Conjugation of a Toll-Like Receptor 7 Agonist to a Monoclonal Antibody Maintains Antigen Binding and Specificity

Bioconjugate chemistry, 2015-08, Vol.26 (8), p.1743-1752

2015

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Trapping of palindromic ligands within native transthyretin prevents amyloid formation

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20483-20488

2010

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Emergent Glycerophospholipid Fluorescent Probes: Synthesis and Applications

Bioconjugate chemistry, 2020-03, Vol.31 (3), p.417-435

2020

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Mild and Rapid Method for the Generation of ortho-(Naphtho)quinone Methide Intermediates

Organic letters, 2012-01, Vol.14 (2), p.584-587

2012

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Organocatalytic Access to a cis-Cyclopentyl-γ-amino Acid: An Intriguing Model of Selectivity and Formation of a Stable 10/12-Helix from the Corresponding γ/α-Peptide

Journal of the American Chemical Society, 2020-01, Vol.142 (3), p.1382-1393

2020

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Highly Enantioselective, Organocatalytic, and Scalable Synthesis of a Rare cis,cis‐Tricyclic Diterpenoid

Chemistry : a European journal, 2020-03, Vol.26 (16), p.3504-3508

2020

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Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions

Organic & biomolecular chemistry, 2005-01, Vol.3 (1), p.84-96

2005

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Organocatalytic Domino Reaction of Cyanosulfones: Access to Complex Cyclohexane Systems with Quaternary Carbon Centers

Organic letters, 2013-03, Vol.15 (6), p.1386-1389

2013

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Recent highlights in modified oligonucleotide chemistry

Organic & biomolecular chemistry, 2007-01, Vol.5 (20), p.3260-3275

Cobb, Alexander J A

2007

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Synthesis and antiviral activity of novel spirocyclic nucleosides

New journal of chemistry, 2018-11, Vol.42 (22), p.18363-18380

2018

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Synthesis and Antiviral Properties of Spirocyclic [1,2,3]-Triazolooxazine Nucleosides

Chemistry : a European journal, 2014-09, Vol.20 (37), p.11685-11689

2014

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Synthesis and Biophysical Characterization of Fingolimod Derivatives as Cardiac Troponin Antagonists

ACS medicinal chemistry letters, 2024-03, Vol.15 (3), p.413-417

2024

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Flow-based bioconjugation of coumarin phosphatidylethanolamine probes: Optimised synthesis and membrane molecular dynamics studies

Biochimica et biophysica acta. Biomembranes, 2024-10, Vol.1866 (7), p.184335, Article 184335

2024

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High Throughput Screen Identifies Small Molecule Effectors That Modulate Thin Filament Activation in Cardiac Muscle

ACS chemical biology, 2021-01, Vol.16 (1), p.225-235

2021

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Crystal Structure and NMR of an α,δ‐Peptide Foldamer Helix Shows Side‐Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic

Angewandte Chemie International Edition, 2023-09, Vol.62 (36), p.e202305326-n/a

International ed. in English, 2023

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Enantioselective Organocatalytic Synthesis of Bicyclic Resorcinols via an Intramolecular Friedel−Crafts‐Type 1,4‐Addition: Access to Cannabidiol Analogues

Advanced synthesis & catalysis, 2021-08, Vol.363 (16), p.4067-4074

2021

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Cover Picture: Crystal Structure and NMR of an α,δ‐Peptide Foldamer Helix Shows Side‐Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic (Angew. Chem. Int. Ed. 36/2023)

Angewandte Chemie International Edition, 2023-09, Vol.62 (36), p.n/a

International ed. in English, 2023

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Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters

Journal of the American Chemical Society, 2009-11, Vol.131 (44), p.16016-16017

2009

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Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to δ(3)-amino acids

Chemical communications (Cambridge, England), 2015-09, Vol.51 (70), p.13558-13561

2015

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High potency of lipid conjugated TLR7 agonist requires nanoparticulate or liposomal formulation

European journal of pharmaceutical sciences, 2018-10, Vol.123, p.268-276

2018

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Targeting C-reactive protein for the treatment of cardiovascular disease

Nature, 2006-04, Vol.440 (7088), p.1217-1221

2006

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5-Pyrrolidin-2-yltetrazole as an asymmetric organocatalyst for the addition of ketones to nitro-olefins

Chemical communications (Cambridge, England), 2004-08 (16), p.1808-1809

2004

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Titelbild: Crystal Structure and NMR of an α,δ‐Peptide Foldamer Helix Shows Side‐Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic (Angew. Chem. 36/2023)

Angewandte Chemie, 2023-09, Vol.135 (36), p.n/a

2023

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AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud

Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts

Targeted Activation of Toll-Like Receptors: Conjugation of a Toll-Like Receptor 7 Agonist to a Monoclonal Antibody Maintains Antigen Binding and Specificity

Trapping of palindromic ligands within native transthyretin prevents amyloid formation

Emergent Glycerophospholipid Fluorescent Probes: Synthesis and Applications

Mild and Rapid Method for the Generation of ortho-(Naphtho)quinone Methide Intermediates

Organocatalytic Access to a cis-Cyclopentyl-γ-amino Acid: An Intriguing Model of Selectivity and Formation of a Stable 10/12-Helix from the Corresponding γ/α-Peptide

Highly Enantioselective, Organocatalytic, and Scalable Synthesis of a Rare cis,cis‐Tricyclic Diterpenoid

Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions

Organocatalytic Domino Reaction of Cyanosulfones: Access to Complex Cyclohexane Systems with Quaternary Carbon Centers

Recent highlights in modified oligonucleotide chemistry

Synthesis and antiviral activity of novel spirocyclic nucleosides

Synthesis and Antiviral Properties of Spirocyclic [1,2,3]-Triazolooxazine Nucleosides

Synthesis and Biophysical Characterization of Fingolimod Derivatives as Cardiac Troponin Antagonists

Flow-based bioconjugation of coumarin phosphatidylethanolamine probes: Optimised synthesis and membrane molecular dynamics studies

High Throughput Screen Identifies Small Molecule Effectors That Modulate Thin Filament Activation in Cardiac Muscle

Crystal Structure and NMR of an α,δ‐Peptide Foldamer Helix Shows Side‐Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic

Enantioselective Organocatalytic Synthesis of Bicyclic Resorcinols via an Intramolecular Friedel−Crafts‐Type 1,4‐Addition: Access to Cannabidiol Analogues

Cover Picture: Crystal Structure and NMR of an α,δ‐Peptide Foldamer Helix Shows Side‐Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic (Angew. Chem. Int. Ed. 36/2023)

Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters

Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to δ(3)-amino acids

High potency of lipid conjugated TLR7 agonist requires nanoparticulate or liposomal formulation

Targeting C-reactive protein for the treatment of cardiovascular disease

5-Pyrrolidin-2-yltetrazole as an asymmetric organocatalyst for the addition of ketones to nitro-olefins

Titelbild: Crystal Structure and NMR of an α,δ‐Peptide Foldamer Helix Shows Side‐Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic (Angew. Chem. 36/2023)

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