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Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

Nature (London), 2011-01, Vol.469 (7328), p.116-120

2011

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Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis

Biochemical journal, 2010-11, Vol.431 (3), p.337-347

2010

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Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase

Nature chemical biology, 2011-05, Vol.7 (7), p.431-433

2011

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Structure of limonene synthase, a simple model for terpenoid cyclase catalysis

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (13), p.5360-5365

2007

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Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis

Plant physiology (Bethesda), 2004-08, Vol.135 (4), p.2098-2105

2004

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Doubly Deuterium-Labeled Patchouli Alcohol from Cyclization of Singly Labeled [2-2H1]Farnesyl Diphosphate Catalyzed by Recombinant Patchoulol Synthase

Journal of the American Chemical Society, 2010-03, Vol.132 (9), p.2998-3008

2010

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Conformational analysis of (+)-germacrene A by variable-temperature NMR and NOE spectroscopy

Tetrahedron, 2007-09, Vol.63 (32), p.7733-7742

2007

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Bornyl Diphosphate Synthase: Structure and Strategy for Carbocation Manipulation by a Terpenoid Cyclase

Proceedings of the National Academy of Sciences - PNAS, 2002-11, Vol.99 (24), p.15375-15380

2002

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Functional identification of rice syn‐copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products

The Plant journal : for cell and molecular biology, 2004-08, Vol.39 (3), p.309-318

2004

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Functional characterization of the rice kaurene synthase-like gene family

Phytochemistry (Oxford), 2007-02, Vol.68 (3), p.312-326

2007

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Functional Characterization of Premnaspirodiene Oxygenase, a Cytochrome P450 Catalyzing Regio- and Stereo-specific Hydroxylations of Diverse Sesquiterpene Substrates

The Journal of biological chemistry, 2007-10, Vol.282 (43), p.31744-31754

2007

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Dissecting Paclitaxel–Microtubule Association: Quantitative Assessment of the 2′-OH Group

Biochemistry (Easton), 2013-04, Vol.52 (13), p.2328-2336

2013

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Probing the Role of the DXDD Motif in Class II Diterpene Cyclases

Chembiochem : a European journal of chemical biology, 2007-05, Vol.8 (8), p.869-874

2007

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Functional Identification of Valerena-1,10-diene Synthase, a Terpene Synthase Catalyzing a Unique Chemical Cascade in the Biosynthesis of Biologically Active Sesquiterpenes in Valeriana officinalis

The Journal of biological chemistry, 2013-02, Vol.288 (5), p.3163-3173

2013

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Alternative Synthesis of the Colorado Potato Beetle Pheromone

Journal of organic chemistry, 2013-10, Vol.78 (20), p.10548-10554

2013

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Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates

ACS chemical biology, 2010-04, Vol.5 (4), p.377-392

2010

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X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis

The Journal of biological chemistry, 2008-05, Vol.283 (22), p.15431-15439

2008

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Taxadiene Synthase-Catalyzed Cyclization of 6-Fluorogeranylgeranyl Diphosphate to 7-Fluoroverticillenes

Journal of the American Chemical Society, 2005-06, Vol.127 (21), p.7834-7842

2005

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16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: Potent Mechanism-Based Inhibitors of Recombinant ent-Kaurene Synthase from Arabidopsis thaliana

Journal of the American Chemical Society, 2007-10, Vol.129 (41), p.12453-12460

2007

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Bisabolyl-Derived Sesquiterpenes from Tobacco 5-Epi-aristolochene Synthase-Catalyzed Cyclization of (2Z,6E)-Farnesyl Diphosphate

Journal of the American Chemical Society, 2010-03, Vol.132 (12), p.4281-4289

2010

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Formation of the Unusual Semivolatile Diterpene Rhizathalene by the Arabidopsis Class I Terpene Synthase TPS08 in the Root Stele Is Involved in Defense against Belowground Herbivory

The Plant cell, 2013-03, Vol.25 (3), p.1108-1125

2013

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Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants

Biochemistry (Easton), 2005-04, Vol.44 (16), p.6153-6163

2005

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An unexpected diterpene cyclase from rice: Functional identification of a stemodene synthase

Archives of biochemistry and biophysics, 2006-04, Vol.448 (1), p.133-140

2006

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Stereochemistry of the Macrocyclization and Elimination Steps in Taxadiene Biosynthesis through Deuterium Labeling

Journal of organic chemistry, 2005-06, Vol.70 (12), p.4667-4675

2005

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Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents

Journal of medicinal chemistry, 2002-05, Vol.45 (11), p.2185-2196

2002

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Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis

Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis

Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase

Structure of limonene synthase, a simple model for terpenoid cyclase catalysis

Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis

Doubly Deuterium-Labeled Patchouli Alcohol from Cyclization of Singly Labeled [2-2H1]Farnesyl Diphosphate Catalyzed by Recombinant Patchoulol Synthase

Conformational analysis of (+)-germacrene A by variable-temperature NMR and NOE spectroscopy

Bornyl Diphosphate Synthase: Structure and Strategy for Carbocation Manipulation by a Terpenoid Cyclase

Functional identification of rice syn‐copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products

Functional characterization of the rice kaurene synthase-like gene family

Functional Characterization of Premnaspirodiene Oxygenase, a Cytochrome P450 Catalyzing Regio- and Stereo-specific Hydroxylations of Diverse Sesquiterpene Substrates

Dissecting Paclitaxel–Microtubule Association: Quantitative Assessment of the 2′-OH Group

Probing the Role of the DXDD Motif in Class II Diterpene Cyclases

Functional Identification of Valerena-1,10-diene Synthase, a Terpene Synthase Catalyzing a Unique Chemical Cascade in the Biosynthesis of Biologically Active Sesquiterpenes in Valeriana officinalis

Alternative Synthesis of the Colorado Potato Beetle Pheromone

Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates

X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis

Taxadiene Synthase-Catalyzed Cyclization of 6-Fluorogeranylgeranyl Diphosphate to 7-Fluoroverticillenes

16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: Potent Mechanism-Based Inhibitors of Recombinant ent-Kaurene Synthase from Arabidopsis thaliana

Bisabolyl-Derived Sesquiterpenes from Tobacco 5-Epi-aristolochene Synthase-Catalyzed Cyclization of (2Z,6E)-Farnesyl Diphosphate

Formation of the Unusual Semivolatile Diterpene Rhizathalene by the Arabidopsis Class I Terpene Synthase TPS08 in the Root Stele Is Involved in Defense against Belowground Herbivory

Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants

An unexpected diterpene cyclase from rice: Functional identification of a stemodene synthase

Stereochemistry of the Macrocyclization and Elimination Steps in Taxadiene Biosynthesis through Deuterium Labeling

Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates: A Potential Route to New Bone Antiresorption and Antiparasitic Agents

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