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A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors

Journal of lipid research, 2024-08, Vol.65 (8), p.100584, Article 100584

2024

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Functions of neutral ceramidase in the Golgi apparatus

Journal of lipid research, 2018-11, Vol.59 (11), p.2116-2125

2018

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NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon

Molecular and Cellular Biology, 2010-06, Vol.30 (11), p.2636-2650

2010

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Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker rats

Molecular metabolism (Germany), 2018-02, Vol.8, p.23-36

2018

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Role of Sphingosine Kinase 1 in Glucolipotoxicity-Induced Early Activation of Autophagy in INS-1 Pancreatic β Cells

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.636

2024

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Mass Spectrometry and Pharmacological Approaches to Measuring Cooption and Reciprocal Activation of Receptor Tyrosine Kinases

Proteomes, 2023-06, Vol.11 (2), p.20

2023

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Glucolipotoxicity impairs ceramide flow from the endoplasmic reticulum to the Golgi apparatus in INS-1 β-cells

PloS one, 2014-10, Vol.9 (10), p.e110875-e110875

2014

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Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease

PloS one, 2014-12, Vol.9 (12), p.e113998

2014

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Ceramidases, roles in sphingolipid metabolism and in health and disease

Advances in biological regulation, 2017-01, Vol.63, p.122-131

2017

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Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis

The Journal of immunology (1950), 2021-03, Vol.206 (6), p.1395-1404

2021

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Neutral ceramidase: Advances in mechanisms, cell regulation, and roles in cancer

Advances in biological regulation, 2019-01, Vol.71, p.141-146

2019

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P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

Oncogene, 2017-11, Vol.36 (47), p.6649-6657

2017

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Sphingolipids in colon cancer

Biochimica et biophysica acta, 2014-05, Vol.1841 (5), p.773-782

2014

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Measurement of neutral ceramidase activity in vitro and in vivo

Analytical biochemistry, 2022-04, Vol.643, p.114577-114577, Article 114577

2022

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AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells

Oncogene, 2018-07, Vol.37 (28), p.3852-3863

2018

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Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia reperfusion injury

Cell death and differentiation, 2010-09, Vol.17 (9), p.1474-1485

2010

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Neutral ceramidase regulates ferroptosis in myeloid-derived suppressor cells

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.164-164.12

2020

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Role of neutral ceramidase in colon cancer

The FASEB journal, 2016-12, Vol.30 (12), p.4159-4171

2016

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Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells

Biochemical journal, 2011-08, Vol.438 (1), p.177-189

2011

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Loss of acid ceramidase in myeloid cells suppresses intestinal neutrophil recruitment

The FASEB journal, 2018-05, Vol.32 (5), p.2339-2353

2018

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A comprehensive measure of Golgi sphingolipid flux using NBD C 6 -ceramide: evaluation of sphingolipid inhibitors

Journal of lipid research, 2024-08, Vol.65 (8), p.100584

2024

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Neutral ceramidase-active site inhibitor chemotypes and binding modes

Bioorganic chemistry, 2023-10, Vol.139, p.106747-106747, Article 106747

2023

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Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis

Prostaglandins & other lipid mediators, 2017-05, Vol.130, p.47-56

2017

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Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells

Scientific reports, 2017-03, Vol.7 (1), p.44867-44867, Article 44867

2017

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Targeting lipid sensing in the central nervous system: new therapy against the development of obesity and type 2 diabetes

Expert opinion on therapeutic targets, 2013-05, Vol.17 (5), p.545-555

2013

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A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors

Functions of neutral ceramidase in the Golgi apparatus

NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon

Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker rats

Role of Sphingosine Kinase 1 in Glucolipotoxicity-Induced Early Activation of Autophagy in INS-1 Pancreatic β Cells

Mass Spectrometry and Pharmacological Approaches to Measuring Cooption and Reciprocal Activation of Receptor Tyrosine Kinases

Glucolipotoxicity impairs ceramide flow from the endoplasmic reticulum to the Golgi apparatus in INS-1 β-cells

Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease

Ceramidases, roles in sphingolipid metabolism and in health and disease

Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis

Neutral ceramidase: Advances in mechanisms, cell regulation, and roles in cancer

P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

Sphingolipids in colon cancer

Measurement of neutral ceramidase activity in vitro and in vivo

AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia reperfusion injury

Neutral ceramidase regulates ferroptosis in myeloid-derived suppressor cells

Role of neutral ceramidase in colon cancer

Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells

Loss of acid ceramidase in myeloid cells suppresses intestinal neutrophil recruitment

A comprehensive measure of Golgi sphingolipid flux using NBD C 6 -ceramide: evaluation of sphingolipid inhibitors

Neutral ceramidase-active site inhibitor chemotypes and binding modes

Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis

Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells

Targeting lipid sensing in the central nervous system: new therapy against the development of obesity and type 2 diabetes

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