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Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis

The Lancet (British edition), 2010-10, Vol.376 (9749), p.1312-1319

2010

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Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials

The Lancet (British edition), 2009-09, Vol.374 (9694), p.989-997

2009

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Cytochrome P-450 Polymorphisms and Response to Clopidogrel

The New England journal of medicine, 2009-01, Vol.360 (4), p.354-362

2009

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Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel: Relationship to Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes

Circulation (New York, N.Y.), 2009-05, Vol.119 (19), p.2553-2560

2009

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Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease

European heart journal, 2009-07, Vol.30 (14), p.1744-1752

2009

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Pharmacogenetics and pharmacogenomics of thienopyridines: clinically relevant?

Fundamental & clinical pharmacology, 2012-02, Vol.26 (1), p.19-26

Close, Sandra L.

2012

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PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes

Journal of thrombosis and thrombolysis, 2016-04, Vol.41 (3), p.374-383

2016

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A Haplotype of the Norepinephrine Transporter (Net) Gene Slc6a2 is Associated with Clinical Response to Atomoxetine in Attention-Deficit Hyperactivity Disorder (ADHD)

Neuropsychopharmacology (New York, N.Y.), 2009-08, Vol.34 (9), p.2135-2142

2009

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Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants

British journal of clinical pharmacology, 2012-01, Vol.73 (1), p.93-105

2012

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TRITON and Beyond: New Insights into the Profile of Prasugrel

Cardiovascular therapeutics, 2012-08, Vol.30 (4), p.e174-e182

2012

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Learning from product labels and label changes: how to build pharmacogenomics into drug-development programs

Pharmacogenomics, 2010-12, Vol.11 (12), p.1637-1647

2010

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ABCB1 GENETIC VARIANTS, PHARMACODYNAMIC RESPONSE, AND CARDIOVASCULAR OUTCOMES FOLLOWING TREATMENT WITH CLOPIDOGREL AND PRASUGREL

Journal of the American College of Cardiology, 2010-03, Vol.55 (10), p.A113.E1056-A113.E1056

2010

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Genomewide association for schizophrenia in the CATIE study: results of stage 1

Molecular psychiatry, 2008-06, Vol.13 (6), p.570-584

2008

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Statistical considerations and challenges for immuno-oncology biomarker studies

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.e14500-e14500

2016

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Clopidogrel pharmacogenetics: metabolism and drug interactions

Drug metabolism and drug interactions, 2011-08, Vol.26 (2), p.45-51

Close, Sandra L

2011

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Genetic Variants in ABCB1, CYP2C19, and Cardiovascular Outcomes Following Treatment with Clopidogrel and Prasugrel

The Lancet (British edition), 2010-10, Vol.376 (9749), p.1312-1319

2010

Volltextzugriff (PDF)

Pharmacodynamic effect and clinical efficacy of clopidogre and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials

The Lancet (British edition), 2009, Vol.374 (9694), p.989-997

2009

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Abstract 1439: Cytochrome P450 Genetic Variants Predict Cardiovascular Outcomes following Treatment with Clopidogrel but not with Prasugrel

Circulation (New York, N.Y.), 2008-10, Vol.118 (suppl_18)

2008

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Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

Cell, 2009-02, Vol.136 (3), p.551-564

2009

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Interactions of Short-Term and Chronic Treadmill Training With Aging of the Left Ventricle of the Heart

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016-08, Vol.71 (8), p.1005-1013

2016

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Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

Nature reviews. Drug discovery, 2010-06, Vol.9 (6), p.435-445

2010

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Association of acute phase proteins with a serum proteomic test in previously treated patients with NSCLC

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.e20649-e20649

2016

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Home-School Collaboration: Enhancing Children's Academic and Social Competence

1992

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Multiplex Assay for Comprehensive Genotyping of Genes Involved in Drug Metabolism, Excretion, and Transport

Clinical chemistry (Baltimore, Md.), 2007-07, Vol.53 (7), p.1222-1230

2007

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Progression of symptoms in the early and middle stages of Huntington disease

Archives of neurology (Chicago), 2001-02, Vol.58 (2), p.273

2001

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Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis

Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials

Cytochrome P-450 Polymorphisms and Response to Clopidogrel

Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel: Relationship to Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes

Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease

Pharmacogenetics and pharmacogenomics of thienopyridines: clinically relevant?

PON1 Q192R genetic variant and response to clopidogrel and prasugrel: pharmacokinetics, pharmacodynamics, and a meta-analysis of clinical outcomes

A Haplotype of the Norepinephrine Transporter (Net) Gene Slc6a2 is Associated with Clinical Response to Atomoxetine in Attention-Deficit Hyperactivity Disorder (ADHD)

Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants

TRITON and Beyond: New Insights into the Profile of Prasugrel

Learning from product labels and label changes: how to build pharmacogenomics into drug-development programs

ABCB1 GENETIC VARIANTS, PHARMACODYNAMIC RESPONSE, AND CARDIOVASCULAR OUTCOMES FOLLOWING TREATMENT WITH CLOPIDOGREL AND PRASUGREL

Genomewide association for schizophrenia in the CATIE study: results of stage 1

Statistical considerations and challenges for immuno-oncology biomarker studies

Clopidogrel pharmacogenetics: metabolism and drug interactions

Genetic Variants in ABCB1, CYP2C19, and Cardiovascular Outcomes Following Treatment with Clopidogrel and Prasugrel

Pharmacodynamic effect and clinical efficacy of clopidogre and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials

Abstract 1439: Cytochrome P450 Genetic Variants Predict Cardiovascular Outcomes following Treatment with Clopidogrel but not with Prasugrel

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

Interactions of Short-Term and Chronic Treadmill Training With Aging of the Left Ventricle of the Heart

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

Association of acute phase proteins with a serum proteomic test in previously treated patients with NSCLC

Home-School Collaboration: Enhancing Children's Academic and Social Competence

Multiplex Assay for Comprehensive Genotyping of Genes Involved in Drug Metabolism, Excretion, and Transport

Progression of symptoms in the early and middle stages of Huntington disease

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