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Efficient Exploration of Sequence Space by Sequence-Guided Protein Engineering and Design

Biochemistry (Easton), 2023-01, Vol.62 (2), p.210-220

2023

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Ancestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding Proteins

Cell chemical biology, 2016-02, Vol.23 (2), p.236-245

2016

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SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency

Nucleic acids research, 2024-10

2024

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Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein

Nature chemical biology, 2018-06, Vol.14 (6), p.542-547

2018

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Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme

Nature communications, 2020-11, Vol.11 (1), p.5945-5945, Article 5945

2020

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Evolutionary repair reveals an unexpected role of the tRNA modification m1G37 in aminoacylation

Nucleic acids research, 2021-12, Vol.49 (21), p.12467-12485

2021

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Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction

Protein science, 2015-09, Vol.24 (9), p.1412-1422

2015

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Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1596, p.71

2017

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The ultra-high affinity transport proteins of ubiquitous marine bacteria

Nature (London), 2024-10, Vol.634 (8034), p.721-728

2024

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The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity

Protein science, 2022-12, Vol.31 (12), p.e4510-n/a

2022

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High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus

Molecular microbiology, 2021-08, Vol.116 (2), p.397-415

2021

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Structural reconstruction of protein ancestry

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (15), p.3897-3902

2017

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Primal World Beliefs

Psychological assessment, 2019-01, Vol.31 (1), p.82-99

2019

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Age and the epidemiology and pathogenesis of tuberculosis

The Lancet (British edition), 2010-05, Vol.375 (9729), p.1852-1854

2010

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Prevalence, natural history, and time-dependent outcomes of a multi-center North American cohort of out-of-hospital cardiac arrest extracorporeal CPR candidates

Resuscitation, 2017-08, Vol.117, p.24-31

2017

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Efficacy and safety of certolizumab pegol in a broad population of patients with active rheumatoid arthritis: results from the REALISTIC phase IIIb study

Rheumatology (Oxford, England), 2012-12, Vol.51 (12), p.2204-2214

2012

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Defining domains: developing consensus-based definitions for foundational domains in OMERACT core outcome sets

Seminars in arthritis and rheumatism, 2024-06, Vol.66, p.152423-152423, Article 152423

2024

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Impact of inter-pregnancy BMI change on perinatal outcomes: a retrospective cohort study

European journal of obstetrics & gynecology and reproductive biology, 2016-10, Vol.205, p.98-104

2016

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PROMPT: Prospective Meta-analysis for Pessary Trials Study Protocol

American journal of perinatology, 2024-05, Vol.41 (S 01), p.e2230-e2237

2024

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Identification of β‑Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions

ACS infectious diseases, 2022-03, Vol.8 (3), p.557-573

2022

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Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population

Brain (London, England : 1878), 2023-07, Vol.146 (7), p.2723-2729

2023

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Adherence and Viral Suppression Among Participants of the Patient-centered Human Immunodeficiency Virus (HIV) Care Model Project: A Collaboration Between Community-based Pharmacists and HIV Clinical Providers

Clinical infectious diseases, 2020-02, Vol.70 (5), p.789-797

2020

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Pediatric Endoscopy in the Era of Coronavirus Disease 2019: A North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper

Journal of pediatric gastroenterology and nutrition, 2020-06, Vol.70 (6), p.741-750

2020

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Efficient Exploration of Sequence Space by Sequence-Guided Protein Engineering and Design

Ancestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding Proteins

SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency

Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein

Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme

Evolutionary repair reveals an unexpected role of the tRNA modification m1G37 in aminoacylation

Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction

Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors

The ultra-high affinity transport proteins of ubiquitous marine bacteria

The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity

High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus

Structural reconstruction of protein ancestry

Primal World Beliefs

Age and the epidemiology and pathogenesis of tuberculosis

Prevalence, natural history, and time-dependent outcomes of a multi-center North American cohort of out-of-hospital cardiac arrest extracorporeal CPR candidates

Establishing an Updated Core Domain Set for Studies in Juvenile Idiopathic Arthritis: A Report from the OMERACT 2018 JIA Workshop

Efficacy and safety of certolizumab pegol in a broad population of patients with active rheumatoid arthritis: results from the REALISTIC phase IIIb study

Defining domains: developing consensus-based definitions for foundational domains in OMERACT core outcome sets

Impact of inter-pregnancy BMI change on perinatal outcomes: a retrospective cohort study

PROMPT: Prospective Meta-analysis for Pessary Trials Study Protocol

Investigation of radiomic signatures for local recurrence using primary tumor texture analysis in oropharyngeal head and neck cancer patients

Identification of β‑Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions

Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population

Adherence and Viral Suppression Among Participants of the Patient-centered Human Immunodeficiency Virus (HIV) Care Model Project: A Collaboration Between Community-based Pharmacists and HIV Clinical Providers

Pediatric Endoscopy in the Era of Coronavirus Disease 2019: A North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper

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