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SYNGAP1: Mind the Gap

Frontiers in cellular neuroscience, 2016-02, Vol.10, p.32-32

2016

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Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses

Cell, 2012-11, Vol.151 (4), p.709-723

2012

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Epilepsy Characteristics in Neurodevelopmental Disorders: Research from Patient Cohorts and Animal Models Focusing on Autism Spectrum Disorder

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10807

2022

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Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling

PLoS biology, 2021-11, Vol.19 (11), p.e3001432-e3001432

2021

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Metabotropic action of postsynaptic kainate receptors triggers hippocampal long-term potentiation

Nature neuroscience, 2017-04, Vol.20 (4), p.529-539

2017

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Understanding intellectual disability and autism spectrum disorders from common mouse models: synapses to behaviour

Open biology, 2019-06, Vol.9 (6), p.180265-180265

2019

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Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model

Scientific reports, 2021-01, Vol.11 (1), p.96-20, Article 96

2021

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SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

eLife, 2024-02, Vol.13

2024

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Rats Smell in Stereo

Science (American Association for the Advancement of Science), 2006-02, Vol.311 (5761), p.666-670

2006

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Differential Regulation of Syngap1 Translation by FMRP Modulates eEF2 Mediated Response on NMDAR Activity

Frontiers in molecular neuroscience, 2019-05, Vol.12, p.97-97

2019

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Chronic postnatal chemogenetic activation of forebrain excitatory neurons evokes persistent changes in mood behavior

eLife, 2020-09, Vol.9

2020

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Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective

Frontiers in molecular neuroscience, 2018-04, Vol.11, p.109

2018

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Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration

EBioMedicine, 2019-12, Vol.50, p.260-273

2019

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A novel autophagy modulator 6-Bio ameliorates SNCA/α-synuclein toxicity

Autophagy, 2017-07, Vol.13 (7), p.1221-1234

2017

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A perspective on molecular signalling dysfunction, its clinical relevance and therapeutics in autism spectrum disorder

Experimental brain research, 2022-10, Vol.240 (10), p.2525-2567

2022

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Epigenetic modulation by small molecule compounds for neurodegenerative disorders

Pharmacological research, 2018-06, Vol.132, p.135-148

2018

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Critical aspects of neurodevelopment

Neurobiology of learning and memory, 2021-04, Vol.180, p.107415-107415, Article 107415

2021

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Pharmacological intervention in young adolescents rescues synaptic physiology and behavioural deficits in Syngap1+/− mice

Experimental brain research, 2022, Vol.240 (1), p.289-309

2022

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Correction to: Identification of an individual with a SYNGAP1 pathogenic mutation in India

Molecular biology reports, 2021-09, Vol.48 (9), p.6663-6663

2021

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SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity

The Journal of neuroscience, 2013-06, Vol.33 (25), p.10447-10452

2013

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Oral Administration of a Specific p300/CBP Lysine Acetyltransferase Activator Induces Synaptic Plasticity and Repairs Spinal Cord Injury

ACS chemical neuroscience, 2024-08, Vol.15 (15), p.2741-2755

2024

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Identification of an individual with a SYNGAP1 pathogenic mutation in India

Molecular biology reports, 2020-11, Vol.47 (11), p.9225-9234

2020

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Correction: SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

eLife, 2024-07, Vol.13

2024

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Neurodegenerative diseases: model organisms, pathology and autophagy

Journal of genetics, 2018-07, Vol.97 (3), p.679-701

2018

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Chemogenetic Activation of Excitatory Neurons Alters Hippocampal Neurotransmission in a Dose-Dependent Manner

eNeuro, 2019-11, Vol.6 (6), p.ENEURO.0124-19.2019

2019

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SYNGAP1: Mind the Gap

Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses

Epilepsy Characteristics in Neurodevelopmental Disorders: Research from Patient Cohorts and Animal Models Focusing on Autism Spectrum Disorder

Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling

Metabotropic action of postsynaptic kainate receptors triggers hippocampal long-term potentiation

Understanding intellectual disability and autism spectrum disorders from common mouse models: synapses to behaviour

Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model

SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

Rats Smell in Stereo

Differential Regulation of Syngap1 Translation by FMRP Modulates eEF2 Mediated Response on NMDAR Activity

Chronic postnatal chemogenetic activation of forebrain excitatory neurons evokes persistent changes in mood behavior

Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective

Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration

A novel autophagy modulator 6-Bio ameliorates SNCA/α-synuclein toxicity

A perspective on molecular signalling dysfunction, its clinical relevance and therapeutics in autism spectrum disorder

Epigenetic modulation by small molecule compounds for neurodegenerative disorders

Critical aspects of neurodevelopment

Pharmacological intervention in young adolescents rescues synaptic physiology and behavioural deficits in Syngap1+/− mice

Correction to: Identification of an individual with a SYNGAP1 pathogenic mutation in India

SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity

Oral Administration of a Specific p300/CBP Lysine Acetyltransferase Activator Induces Synaptic Plasticity and Repairs Spinal Cord Injury

Identification of an individual with a SYNGAP1 pathogenic mutation in India

Correction: SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration

Neurodegenerative diseases: model organisms, pathology and autophagy

Chemogenetic Activation of Excitatory Neurons Alters Hippocampal Neurotransmission in a Dose-Dependent Manner

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